Results 251 to 260 of about 5,115,827 (299)
Some of the next articles are maybe not open access.
Recombinant Proteins: Evolution to their Therapeutic Potential
Protein and Peptide LettersRecombinant proteins, which are produced using recombinant DNA technology, have transformed the domains of biotechnology and biomedicine by allowing the production of proteins that are often expensive or difficult to obtain from natural sources.
Dr Krishna Gupta +2 more
exaly +3 more sources
Human cells: New platform for recombinant therapeutic protein production
Protein Expression and Purification, 2012The demand for recombinant therapeutic proteins is significantly increasing. There is a constant need to improve the existing expression systems, and also developing novel approaches to face the therapeutic proteins demands. Human cell lines have emerged as a new and powerful alternative for the production of human therapeutic proteins because this ...
Virginia Picanco-Castro, Kamilla Swiech
exaly +3 more sources
Production of recombinant and therapeutic proteins in microalgae
Current Opinion in Biotechnology, 2022Microalgae is emerging as a promising platform for the production of recombinant proteins of therapeutic importance. Since microalgae are safe for oral consumption and some microalgal species can form extracellular vesicles, they can potentially be used as edible vaccines or drug-delivery vehicles in addition to their status as naturally rich sources ...
Anirban, Banerjee, Valerie, Ward
openaire +2 more sources
[Recombinant proteins as therapeutic compounds in clinical oncology]
, 2011 The in vitro production of recombinant protein molecules has fostered a tremendous interest in their clinical application for treatment and support of cancer patients. Therapeutic proteins include monoclonal antibodies, interferons, and haematopoietic growth factors.
Fey, Martin, Martin, F
openaire +3 more sources
Recombinant Therapeutic Protein Vaccines
Protein & Peptide Letters, 2013Recombinant technology has ushered in a new era for the pharmaceutical industry. Protein therapeutics, including plasma-derived products and antibodies obtained from the serum of infected patients, have been successfully adopted and utilized to treat various indications.
Satoshi, Ohtake, Tsutomu, Arakawa
openaire +2 more sources
Induction of Tolerance to Recombinant Therapeutic Proteins
Journal of Interferon & Cytokine Research, 2001The specific IgM and IgG antibody responses to subcutaneous (s.c.) treatment of mice with recombinant human IFN-alpha2a (rHuIFN-alpha2a) or IFN-beta were inhibited in a dose-dependent manner by prior oromucosal (o.m.) administration of rHuIFN-alpha2a or IFN-beta, respectively. Pretreatment of animals once a day for 7 days by the o.m.
J F, Meritet, C, Maury, M G, Tovey
openaire +2 more sources
Recombinant Protein Based Therapeutics for IPF
Inflammation & Allergy-Drug Targets, 2013Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, irreversible, and usually fatal interstitial lung disease of unknown cause [1, 2]. The aetiology of IPF is unknown, although identified risk factors for IPF include cigarette smoking, environmental exposures, microbial agents, age, male gender and gastroesophageal reflux disease (GERD ...
Joseph M, Parker +2 more
openaire +2 more sources
Therapeutic advances in rheumatology with the use of recombinant proteins
Nature Clinical Practice Rheumatology, 2008Antibody engineering and protein design have led to the creation of a new era of targeted anti-inflammatory therapies in rheumatology. Recombinant DNA technologies have enabled the selection and humanization of specific antibody fragments in order to develop therapeutic reagents of any specificity that can be 'armed' to deliver effective anti ...
Achim, Rothe +2 more
openaire +2 more sources
Manufacturing of recombinant therapeutic proteins in microbial systems
Biotechnology Journal, 2006AbstractRecombinant therapeutic proteins have gained enormous importance for clinical applications. The first recombinant products have been produced in E. coli more than 20 years ago. Although with the advent of antibody‐based therapeutics mammalian expression systems have experienced a major boost, microbial expression systems continue to be widely ...
Klaus, Graumann, Andreas, Premstaller
openaire +2 more sources
Glycosylation control technologies for recombinant therapeutic proteins
Applied Microbiology and Biotechnology, 2018Protein glycosylation is a very important quality attribute of any biopharmaceutical product as it affects the efficacy, serum half-life, and antigenicity of a molecule. The present expression hosts commercially utilized for a recombinant glycoprotein production generally cannot produce a desired and uniform glycan composition and generally exhibit non-
Sanjeev K. Gupta, Pratyoosh Shukla
openaire +2 more sources