Results 211 to 220 of about 356,092 (265)

Recombinant live virus vaccines

Immunology Letters, 1987
Many successful vaccines are based on live attenuated viruses. An attractive idea is to genetically engineer these live attenuated vaccines so that they express protective antigens from other pathogens. Vaccinia virus, the smallpox vaccine, can be considered as the prototype for this sort of approach.
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Infectious Recombinant Vectored Virus Vaccines

1989
Publisher Summary This chapter presents the development and the potential of infectious recombinant vectored virus vaccines. Experimental immunizations with infectious virus vectors carrying one or more heterologous genes for immunogenic proteins have been remarkably successful in experimental animals systems.
J J, Esposito, F A, Murphy
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Virus recombinants et virus synthétiques

Annales des Mines - Réalités industrielles, 2013
L’émergence de la biologie moléculaire et des technologies associées, qui ont constitué le terreau à partir duquel ont pu se structurer les prémices de la biologie de synthèse, est intimement liée à l’histoire de la virologie. Même si la biologie de synthèse ne s’est répandue dans la communauté scientifique qu’à partir des années 2000, l’ingénierie ...
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Recombinant Influenza Virus Vectors

Future Virology, 2007
Newly optimized reverse genetics techniques have allowed influenza researchers to generate recombinant influenza viruses expressing mutant viral proteins, as well as foreign proteins. Approaches include the insertion of noninfluenza epitopes and polypeptides into viral glycoproteins, foreign open reading frames as additional segments, and the fusion of
Luis Martínez-Sobrido, Adolfo García-Sastre   +1 more
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Intraocular Delivery of Recombinant Virus

2003
In the past 5 yr, advances in technology have been made that allow efficient somatic transfer of functional genes to target cells in the eye in vivo. The ability to deliver functional genes to these cells is due primarily to the development of viral vectors-viruses in which various replicative functions have been replaced with transgene cassettes ...
F Q, Liang, V, Anand, A M, Maguire, J, Bennett   +3 more
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