Results 21 to 30 of about 1,656,346 (308)

Possible repair of UV-damaged Spodoptera littoralis nucleopolyhedrovirus DNA via generation of mutant carrying photolyase gene with DNA repair activity

open access: yesEgyptian Journal of Biological Pest Control, 2023
Background Baculoviruses can be inactivated by ultraviolet (UV) light, which limits their application as an efficient biopesticide. In an attempt to enhance virus resistance to UV inactivation, a photolyase gene, isolated from Spodoptera litura ...
Wael Elmenofy   +5 more
doaj   +1 more source

Recombination in Hepatitis C Virus [PDF]

open access: yesViruses, 2011
Hepatitis C virus (HCV) is a Flavivirus with a positive-sense, single-stranded RNA genome of about 9,600 nucleotides. It is a major cause of liver disease, infecting almost 200 million people all over the world. Similarly to most RNA viruses, HCV displays very high levels of genetic diversity which have been used to differentiate six major genotypes ...
Fernando González-Candelas   +2 more
openaire   +5 more sources

A recombinant rabies virus encoding two copies of the glycoprotein gene confers protection in dogs against a virulent challenge. [PDF]

open access: yesPLoS ONE, 2014
The rabies virus (RABV) glycoprotein (G) is the principal antigen responsible for the induction of virus neutralizing antibodies (VNA) and is the major modality of protective immunity in animals.
Xiaohui Liu   +8 more
doaj   +1 more source

Development of an Adeno-Associated Virus-Vectored SARS-CoV-2 Vaccine and Its Immunogenicity in Mice

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Owing to the outbreak of the novel coronavirus (SARS-CoV-2) worldwide at the end of 2019, the development of a SARS-CoV-2 vaccine became an urgent need.
Xi Qin   +18 more
doaj   +1 more source

Expression of the murine cytomegalovirus glycoprotein H by recombinant vaccinia virus [PDF]

open access: yes, 1994
The sequence of the gene encoding glycoprotein H (gH) of murine cytomegalovirus (MCMV) strain Smith was determined and compared with the sequence of the gH of MCMV strain K181. Transcriptional analysis showed that gH is encoded by a large mRNA of 5.0 kb,
Rapp, Maria   +4 more
core   +1 more source

Naturally occurring genotype 2b/1a hepatitis C virus in the United States

open access: yesVirology Journal, 2011
Background Hepatitis C Virus (HCV) infected patients are frequently repeatedly exposed to the virus, but very few recombinants between two genotypes have been reported.
Striker Rob   +4 more
doaj   +1 more source

Construction and characterization of a contagious ecthyma virus double-gene deletion strain and evaluation of its potential as a live-attenuated vaccine in goat

open access: yesFrontiers in Immunology, 2022
Contagious ecthyma is a highly contagious viral disease with zoonotic significance caused by orf virus (ORFV) that affects domestic, ruminants and humans.
Zhen Zhu   +8 more
doaj   +1 more source

Recombination confounds the early evolutionary history of human immunodeficiency virus type 1: Subtype G is a circulating recombinant form [PDF]

open access: yes, 2007
Human immunodeficiency virus type I (HIV-1) is classified in nine subtypes (A to D, F, G, H, J, and K), a number of subsubtypes, and several circulating recombinant forms (CRFs).
Vandamme, Anne-Mieke   +8 more
core   +1 more source

Construction and Rescue of a Rabies Virus with Duplicated Glycoprotein Gene

open access: yesVaccine Research, 2021
Introduction: Rabies is almost always fatal but entirely preventable through proper vaccination. Inadequacy of costly high-quality cell culture vaccines is sometimes a bottleneck for expanded rabies control plans.
Ashkan Alamdary   +3 more
doaj   +1 more source

Construction of three strains of recombinant oncolytic vaccinia virus and their anti-tumor activity [PDF]

open access: yesJichu yixue yu linchuang, 2020
Objective The aim of this study is to construct a recombinant oncolytic vaccinia virus with CCL5 and SSTR2 genes and to detect its antitumor activity. Methods Recombinant vaccinia virus eukaryotic expression plasmid pSC65-CCL5-SSTR2-Luc+ was constructed.
LI Dan-yang, FANG Jing-jing, TANG Hui
doaj  

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