Results 31 to 40 of about 1,656,346 (308)

Western equine encephalitis virus is a recombinant virus. [PDF]

Proceedings of the National Academy of Sciences, 1988
The alphaviruses are a group of 26 mosquito-borne viruses that cause a variety of human diseases. Many of the New World alphaviruses cause encephalitis, whereas the Old World viruses more typically cause fever, rash, and arthralgia. The genome is a single-stranded nonsegmented RNA molecule of + polarity; it is about 11,700 nucleotides in length ...
Hahn, Chang S., Lustig, Shlomo, Strauss, Ellen G., Strauss, James H.   +3 more
openaire   +3 more sources

Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]

, 2013
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L, Bulmer-Thomas, B., Banyard, AC, Selden, D., Altmann, F, Craig van Dolleweerd (406086), David Selden (4911475), Selden, D, Ashley C Banyard (16267520), Both, L., Banyard, A.C., Edward Wright (4468198), Bulmer-Thomas, B, Fooks, AR, Friedrich Altmann (33138), Wright, E, van Dolleweerd, C., Fooks, A.R., Ma, J.K.C., Julian K C Ma (16267529), Leonard Both (16267517), van Dolleweerd, C, Ma, JK, Wright, E., Altmann, F., Anthony R Fooks (16267526), Bianca Bulmer-Thomas (16267523)   +26 more
core   +1 more source

SAFETY AND IMMUNOGENICITY OF COLD-ADAPTED RECOMBINANT INFLUENZA VECTOR EXPRESSING ESAT-6 AND AG85А ANTIGENS OF M. TUBERCULOSIS

Вопросы вирусологии, 2017
Recombinant viral vectors represent one of the most promising platforms for creating a new generation of vaccines against tuberculosis. We constructed a vaccine candidate based on a cold-adapted influenza vector with a truncated NS1 protein containing an
M. V. Sergeeva, A. A. Pulkina, K. A. Vasiliev, E. A. Romanovskaya-Romanko, A. B. Komissarov, O. A. Kuchur, A. Yu. Egorov, L. M. Tsybalova, M. A. Stukova   +8 more
doaj   +1 more source

Virus-neutralizing monoclonal antibody expressed in milk of transgenic mice provides full protection against virus-induced encephalitis [PDF]

, 2001
Neutralizing antibodies represent a major host defense mechanism against viral infections. In mammals, passive immunity is provided by neutralizing antibodies passed to the offspring via the placenta or the milk as immunoglobulin G and secreted ...
Pewe, L, John Webster, Whitelaw, C B, Andreas F. Kolb, Perlman, S, Siddell, S G, Stanley Perlman, C. Bruce A. Whitelaw, Stuart G. Siddell, Webster, J, Kolb, A F, Lecia Pewe   +11 more
core   +1 more source

A new Defective Helper RNA to produce recombinant Sindbis virus that infects neurons but does not propagate

Frontiers in Neuroanatomy, 2016
Recombinant Sindbis viruses are important tools in neuroscience because they combine rapid and high transgene expression with a capacity to carry large transgenes.
Justus M Kebschull, Justus M Kebschull, Pedro eGarcia da Silva, Anthony M Zador   +3 more
doaj   +1 more source

The splicing factor proline-glutamine rich (SFPQ/PSF) is involved in influenza virus transcription. [PDF]

, 2011
The influenza A virus RNA polymerase is a heterotrimeric complex responsible for viral genome transcription and replication in the nucleus of infected cells. We recently carried out a proteomic analysis of purified polymerase expressed in human cells and
Juan Ortín, Landeras-Bueno, Sara, Jorba, N, Sara Landeras-Bueno, Ortín Juan, Pérez-Cidoncha, Maite, Pérez-Cidoncha, M, Núria Jorba, Landeras-Bueno Sara, Pérez-Cidoncha Maite, Landeras-Bueno, S, Ortín, J, Ortín, Juan, Jorba, Núria, Maite Pérez-Cidoncha, Jorba Núria   +15 more
core   +2 more sources

Recombination with Herpes Simplex Virus [PDF]

Journal of General Microbiology, 1955
Summary: The behaviour of six strains of herpes simplex virus was studied. Marked differences were noted in the type of lesion formed and the rate of attachment when the strains were inoculated on to the chorio-allantois, and in the behaviour of strains inoculated intracerebrally into mice or on to the cornea of the rabbit.
openaire   +2 more sources

Identification of the murine cytomegalovirus glycoprotein B gene and its expression by recombinant vaccinia virus [PDF]

, 1992
The gene encoding glycoprotein B (gB) of murine cytomegalovirus (MCMV) strain Smith was identified, sequenced, and expressed by recombinant vaccinia virus.
Rapp, Maria, Bühler, Bernhard, Koszinowski, Ulrich H., Messerle, Martin, Keil, Günther M., Tannheimer, Michael   +5 more
core   +1 more source

A Recombinant Porcine Reproductive and Respiratory Syndrome Virus Stably Expressing DsRed Protein Based on Bacterial Artificial Chromosome System

Frontiers in Microbiology, 2022
Recombinant viruses possessing reporter proteins as tools are widely applied in investigating viral biology because of the convenience for observation. Previously, we generated a recombinant pathogenic porcine reproductive and respiratory syndrome virus (
Na Li, Yiyi Zhang, Lunguang Yao, Yunpeng Shi, Qin Zhao, Baicheng Huang, Yani Sun   +6 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source