Results 11 to 20 of about 1,036,111 (281)
Genome-wide mapping of binding sites of the transposase-derived SETMAR protein in the human genome
Computational and Structural Biotechnology Journal, 2021 Throughout evolution, DNA transposons provide a recurrent supply of genetic information to give rise to novel gene functions by fusion of their transposase domain to various domains of host-encoded proteins.
Márton Miskei +10 more
doaj +1 more source
Mechanism of substrate hydrolysis by the human nucleotide pool sanitiser DNPH1
Nature Communications, 2023 Poly(ADP-ribose) polymerase (PARP) inhibitors are used in the clinic to treat BRCA-deficient breast, ovarian and prostate cancers. As their efficacy is potentiated by loss of the nucleotide salvage factor DNPH1 there is considerable interest in the ...
Neil J. Rzechorzek +7 more
doaj +1 more source
Computational and Structural Biotechnology Journal, 2021 Flap endonuclease 1 (FEN1) is an important component of the intricate molecular machinery for DNA replication and repair. FEN1 is a structure-specific 5′ nuclease that cleaves nascent single-stranded 5′ flaps during the maturation of Okazaki fragments ...
Mohamed A. Sobhy +5 more
doaj +1 more source
Determination of the trap-assisted recombination strength in polymer light emitting diodes [PDF]
, 2011 The recombination processes in poly(p-phenylene vinylene) based polymer light-emitting diodes (PLEDs) are investigated. Photogenerated current measurements on PLED device structures reveal that next to the known Langevin recombination also trap-assisted ...
Gert-Jan A. H. Wetzelaer +6 more
core +4 more sources
Impact of Nuclear Export Pathway on Cytoplasmic HIV-1 RNA Transport Mechanism and Distribution
mBio, 2020 HIV-1 full-length RNA (referred to as HIV-1 RNA here) serves as the viral genome in virions and as a template for Gag/Gag-Pol translation. We previously showed that HIV-1 RNA, which is exported via the CRM1 pathway, travels in the cytoplasm mainly ...
Jianbo Chen +7 more
doaj +1 more source
Personalized genome structure via single gamete sequencing
Genome Biology, 2021 Genetic maps have been fundamental to building our understanding of disease genetics and evolutionary processes. The gametes of an individual contain all of the information required to perform a de novo chromosome-scale assembly of an individual’s genome,
Ruqian Lyu +3 more
doaj +1 more source
Recombination: Homologous recombination branches out [PDF]
Current Biology, 2001 Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
openaire +2 more sources
, 1995 The present study contributes to a better understanding of the atomic Xe laser as a powerful IR source. Several important phenomena like the dependence of both the observed optimized input power and maximum output power on the square of the gas density ...
Botma, H. +3 more
core +2 more sources
Bioactive Materials, 2023 As a renewable and sustainable source for energy, environment, and biomedical applications, microalgae and microalgal biodiesel have attracted great attention.
Guoxia Zheng +10 more
doaj +1 more source
Primordial helium recombination. I. Feedback, line transfer, and continuum opacity [PDF]
, 2007 Precision measurements of the cosmic microwave background temperature anisotropy on scales ℓ>500 will be available in the near future. Successful interpretation of these data is dependent on a detailed understanding of the damping tail and cosmological ...
A. Burgess +19 more
core +3 more sources