Results 11 to 20 of about 1,224,382 (402)
Adaptation of HIV-1/HIV-2 Chimeras with Defects in Genome Packaging and Viral Replication
mBio, 2022 Frequent recombination is a hallmark of retrovirus replication. In rare cases, recombination occurs between distantly related retroviruses, generating novel viruses that may significantly impact viral evolution and public health.
Jonathan M. O. Rawson +10 more
doaj +1 more source
Reducing the impact of Auger recombination in quasi-2D perovskite light-emitting diodes
Nature Communications, 2021 Rapid Auger recombination represents an important challenge faced by quasi-2D perovskites, which induces resulting perovskite light-emitting diodes’ (PeLEDs) efficiency roll-off.
Yuanzhi Jiang +10 more
semanticscholar +1 more source
Viruses, 2021 The 3C-like protease (3CLpro) of SARS-CoV-2 is considered an excellent target for COVID-19 antiviral drug development because it is essential for viral replication and has a cleavage specificity distinct from human proteases.
Jonathan M. O. Rawson +4 more
doaj +1 more source
NODULIN HOMEOBOX is required for heterochromatin homeostasis in Arabidopsis
Nature Communications, 2022 Arabidopsis NDX was previously reported as a regulator of euchromatic gene expression. Here the authors show that NDX functions at pericentromeric regions and regulates heterochromatin homeostasis by controlling siRNA production and non-CG methylation.
Zsolt Karányi +11 more
doaj +1 more source
Evolution of the recombination regulator PRDM9 in minke whales
BMC Genomics, 2022 Background PRDM9 is a key regulator of meiotic recombination in most metazoans, responsible for reshuffling parental genomes. During meiosis, the PRDM9 protein recognizes and binds specific target motifs via its array of C2H2 zinc-fingers encoded by a ...
Elena Damm +3 more
doaj +1 more source
Microbiology Spectrum, 2022 HIV-1 must package its RNA genome to generate infectious viruses. Recent studies have revealed that during genome packaging, HIV-1 not only excludes cellular mRNAs, but also distinguishes among full-length viral RNAs. Using NL4-3 and MAL molecular clones,
Jonathan M. O. Rawson +5 more
doaj +1 more source
Wolbachia and recombination [PDF]
Trends in Genetics, 2001 The endocellular bacterium Wolbachia manipulates its hosts’ reproduction in an impressive variety of ways: it can induce male killing, feminization, thelytokous parthenogenesis and cytoplasmic incompatibility (CI; embryonic mortality resulting from crosses between Wolbachia-infected males and uninfected females).
Charlat, Sylvain, Merçot, Hervé
openaire +5 more sources
Recombination in Wolbachia [PDF]
Current Biology, 2001 Wolbachia are widely distributed intracellular bacteria that cause a number of reproductive alterations in their eukaryotic hosts. Such alterations include the induction of parthenogenesis, feminization, cytoplasmic incompatibility, and male killing [1-11].
Jeremy D. Bartos, John H. Werren
openaire +3 more sources
Virus Evolution, 2020 For the past 20 years, the recombination detection program (RDP) project has focused on the development of a fast, flexible, and easy to use Windows-based recombination analysis tool.
D. Martin +8 more
semanticscholar +1 more source
Personalized genome structure via single gamete sequencing
Genome Biology, 2021 Genetic maps have been fundamental to building our understanding of disease genetics and evolutionary processes. The gametes of an individual contain all of the information required to perform a de novo chromosome-scale assembly of an individual’s genome,
Ruqian Lyu +3 more
doaj +1 more source