Results 11 to 20 of about 1,295,521 (333)
Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. [PDF]
The Cre-loxP system is invaluable for spatial and temporal control of gene knockout, knockin, and reporter expression in the mouse nervous system. However, we report varying probabilities of unexpected germline recombination in distinct Cre driver lines ...
Abumaria, Nashat+55 more
core +2 more sources
Determination of the trap-assisted recombination strength in polymer light emitting diodes [PDF]
The recombination processes in poly(p-phenylene vinylene) based polymer light-emitting diodes (PLEDs) are investigated. Photogenerated current measurements on PLED device structures reveal that next to the known Langevin recombination also trap-assisted ...
Gert-Jan A. H. Wetzelaer+6 more
core +4 more sources
The Landscape of Realized Homologous Recombination in Pathogenic Bacteria [PDF]
Recombination enhances the adaptive potential of organisms by allowing genetic variants to be tested on multiple genomic backgrounds. Its distribution in the genome can provide insight into the evolutionary forces that underlie traits, such as the ...
Didelot, X+6 more
core +2 more sources
Primordial helium recombination. I. Feedback, line transfer, and continuum opacity [PDF]
Precision measurements of the cosmic microwave background temperature anisotropy on scales ℓ>500 will be available in the near future. Successful interpretation of these data is dependent on a detailed understanding of the damping tail and cosmological ...
A. Burgess+19 more
core +3 more sources
The coronavirus proofreading exoribonuclease mediates extensive viral recombination
Coronaviruses (CoVs) emerge as zoonoses and cause severe disease in humans, demonstrated by the SARS-CoV-2 (COVID-19) pandemic. RNA recombination is required during normal CoV replication for subgenomic mRNA (sgmRNA) synthesis and generates defective ...
J. Gribble+8 more
semanticscholar +1 more source
Genetic recombination is used as a tool for modifying the composition of poxvirus genomes in both discovery and applied research. This review documents the history behind the development of these tools as well as what has been learned about the processes that catalyze virus recombination and the links between it and DNA replication and repair.
openaire +3 more sources
RDP3: a flexible and fast computer program for analyzing recombination
Summary: RDP3 is a new version of the RDP program for characterizing recombination events in DNA-sequence alignments. Among other novelties, this version includes four new recombination analysis methods (3SEQ, VISRD, PHYLRO and LDHAT), new tests for ...
D. Martin+5 more
semanticscholar +1 more source
Search and recombination are important mechanisms in the creativity phase of innovation. Digital transformation and the resulting pervasive digitalization of the innovation function have often been associated with increasing possibilities for search and ...
Gianvito Lanzolla+2 more
semanticscholar +1 more source
Recombination by Replication [PDF]
The evidence summarized above strongly suggests that E. coli cells deal with exposed double-stranded ends by a process that requires both homologous recombination and DNA replication functions. This process could lead to recombinant formation. Importantly, inhibition of recombination-dependent replication in priA null mutants does not completely block ...
openaire +3 more sources
Recombination and Replication [PDF]
The links between recombination and replication have been appreciated for decades and it is now generally accepted that these two fundamental aspects of DNA metabolism are inseparable: Homologous recombination is essential for completion of DNA replication and vice versa.
Michelle Hawkins+2 more
openaire +3 more sources