Results 31 to 40 of about 694,507 (206)

The effects of recombination rate on the distribution and abundance of transposable elements [PDF]

, 2008
Transposable elements (TEs) often accumulate in regions of the genome with suppressed recombination. But it is unclear whether this pattern reflects a reduction in the efficacy of selection against deleterious insertions or a relaxation of ectopic ...
Charlesworth, Brian, Dolgin, Elie S.
core   +1 more source

Sequence diversity and potential recombination events in the coat protein gene of Apple stem pitting virus. [PDF]

, 2011
The variability of the Apple stem pitting virus (ASPV) coat protein (CP) gene was investigated. The CP gene of ten virus isolates from apple and pear trees was sequenced.
Paweł Siedlecki, Beata Komorowska, Malinowski, Tadeusz, Komorowska, Beata, Szymon Kaczanowski, Tadeusz Malinowski, Beata Hasiów-Jaroszewska, Kaczanowski, Szymon, Hasiów-Jaroszewska, Beata, Siedlecki, Paweł   +9 more
core   +2 more sources

λ Recombination and Recombineering

EcoSal Plus, 2016
The bacteriophage λ Red homologous recombination system has been studied over the past 50 years as a model system to define the mechanistic details of how organisms exchange DNA segments that share extended regions of homology. The λ Red system proved useful as a system to study because recombinants could be easily generated by co ...
openaire   +2 more sources

Meiotic Crossover Patterning

Frontiers in Cell and Developmental Biology, 2021
Proper number and placement of meiotic crossovers is vital to chromosome segregation, with failures in normal crossover distribution often resulting in aneuploidy and infertility.
Nila M. Pazhayam, Carolyn A. Turcotte, Jeff Sekelsky, Jeff Sekelsky, Jeff Sekelsky   +4 more
doaj   +1 more source

Bayesian modeling of recombination events in bacterial populations [PDF]

, 2008
Background: We consider the discovery of recombinant segments jointly with their origins within multilocus DNA sequences from bacteria representing heterogeneous populations of fairly closely related species.
Marttinen, P., Hanage William P, Mahenthiralingam Eshwar, Adam Baldwin, Jukka Corander, Marttinen Pekka, Hanage, William P., Pekka Marttinen, Hanage, W. P., Marttinen, Pekka, Dowson, Christopher G., Baldwin, A., Baldwin Adam, Dowson, C., Chris Dowson, Corander, J., Baldwin, Adam, Dowson Chris, William P Hanage, Eshwar Mahenthiralingam, Corander Jukka, Mahenthiralingam, Eshwar   +21 more
core   +1 more source

How to recover from a bad start: adaptation of HIV-1 transcription start site mutants during serial passaging in culture

Journal of Virology
HIV-1 uses neighboring sequences as transcription start sites and generates multiple unspliced transcripts, including two major transcripts with three guanosines (3G) or one guanosine (1G) at the 5′ end. Although only differing by 2-nt, 3G RNA and 1G RNA
Olga A. Nikolaitchik, Akhil Chameettachal, Saiful Islam, Zetao Cheng, Krista Delviks-Frankenberry, Brandon F. Keele, Vinay K. Pathak, Wei-Shau Hu   +7 more
doaj   +1 more source

Elements in the 5′ Untranslated Region of Viral RNA Important for HIV Gag Recognition and Cross-Packaging

Viruses
During retrovirus assembly, Gag packages unspliced viral RNA as the virion genome. Genome packaging is usually specific with occasional exceptions of cross-packaging RNA from distantly related retroviruses.
Zetao Cheng, Olga A. Nikolaitchik, Alice Duchon, Jonathan M. O. Rawson, Vinay K. Pathak, Wei-Shau Hu   +5 more
doaj   +1 more source

Regional differences in recombination hotspots between two chicken populations [PDF]

, 2010
Background Although several genetic linkage maps of the chicken genome have been published, the resolution of these maps is limited and does not allow the precise identification of recombination hotspots. The availability of more than 3.2 million SNPs in
Veenendaal, A., Elferink Martin G, van As, P., van As Pieter, Crooijmans, R.P.M.A., Elferink, M.G., Groenen, M.A.M., Groenen Martien AM, Crooijmans Richard PMA, Veenendaal Tineke, As, P., van   +10 more
core   +1 more source

Development of a Complementation Assay to Monitor Pan-Coronavirus 3C-like Protease Activity

Viruses
Coronaviruses pose a global pandemic threat, making development of a pan-coronavirus inhibitor crucial for preparedness and containment in the event of a new coronavirus outbreak.
Akhil Chameettachal, Alice Duchon, Matthew A. Brown, Jonathan M. O. Rawson, Vinay K. Pathak, Wei-Shau Hu   +5 more
doaj   +1 more source

Whole genome phylogenies reflect the distributions of recombination rates for many bacterial species

eLife, 2021
Although recombination is accepted to be common in bacteria, for many species robust phylogenies with well-resolved branches can be reconstructed from whole genome alignments of strains, and these are generally interpreted to reflect clonal relationships.
Thomas Sakoparnig, Chris Field, Erik van Nimwegen   +2 more
doaj   +1 more source