Determinants of selectivity in Xer site-specific recombination
, 1996 A remarkable property of some DNA-binding proteins that can interact with and pair distant DNA segments is that they mediate their biological function only when their binding sites are arranged in a specific configuration. Xer site-specific recombination
Blakely, G, Sherratt, D
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Sequence diversity and potential recombination events in the coat protein gene of Apple stem pitting virus. [PDF]
, 2011 The variability of the Apple stem pitting virus (ASPV) coat protein (CP) gene was investigated. The CP gene of ten virus isolates from apple and pear trees was sequenced.
Paweł Siedlecki +9 more
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Development of a Complementation Assay to Monitor Pan-Coronavirus 3C-like Protease Activity
VirusesCoronaviruses pose a global pandemic threat, making development of a pan-coronavirus inhibitor crucial for preparedness and containment in the event of a new coronavirus outbreak.
Akhil Chameettachal +5 more
doaj +1 more source
Electrical and photoelectrical properties of MoN/n-Si surface-barrier structures [PDF]
Радиофизика и электроника, 2019 Subject and purpose. The subject of research is the electrical and photoelectric properties of the МoN/n-Si heterostructure fabricated for the first time by means of the deposition of thin film of molybdenum nitride (n-type conductivity) by the reactive ...
M.M. Solovan, P.D. Maryanchuk
doaj +1 more source
Recombination modulates how selection affects linked sites in Drosophila
, 2012 One of the most influential observations in molecular evolution has been a strong association between regional recombination rate and amount of nucleotide polymorphism in those genomic regions, interpreted as evidence for ubiquitous natural selection ...
Caiti S. Smukowski +8 more
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
sequenceLDhot: Detecting Recombination Hotspots. [PDF]
, 2006 Motivation: There is much local variation in recombination rates across the human genome—with the majority of recombination occuring in recombination hotspots—short regions of around ~2 kb in length that have much higher recombination rates than ...
Fearnhead, Paul
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Genomic analysis of meiotic recombination in social insects [PDF]
, 2022 Meiotic recombination is a key event of sexual reproduction in higher eukaryotes that shuffles allele combinations and promotes accurate segregation of chromosomes. The rate of meiotic recombination varies within and across species.
Waiker, Prashant +1 more
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Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Diversity and recombination in Wolbachia and Cardinium from Bryobia spider mites [PDF]
, 2012 Background Wolbachia and Cardinium are endosymbiotic bacteria infecting many arthropods and manipulating host reproduction. Although these bacteria are maternally transmitted, incongruencies between phylogenies of host and parasite suggest an additional ...
Vera I D Ros +7 more
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