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Recombination: Homologous recombination branches out [PDF]
Current Biology, 2001 Homologous recombination can be divided into three key steps: strand exchange, branch migration and resolution. The identification of a protein complex that catalyses branch migration and Holliday junction resolution argues that the mechanism of homologous recombination is conserved from bacteria to man.
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Pathogens, 2022 Genetic recombination is used as a tool for modifying the composition of poxvirus genomes in both discovery and applied research. This review documents the history behind the development of these tools as well as what has been learned about the processes that catalyze virus recombination and the links between it and DNA replication and repair.
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Recombination by Replication [PDF]
Cell, 1996 The evidence summarized above strongly suggests that E. coli cells deal with exposed double-stranded ends by a process that requires both homologous recombination and DNA replication functions. This process could lead to recombinant formation. Importantly, inhibition of recombination-dependent replication in priA null mutants does not completely block ...
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Recombination and Replication [PDF]
Cold Spring Harbor Perspectives in Biology, 2014 The links between recombination and replication have been appreciated for decades and it is now generally accepted that these two fundamental aspects of DNA metabolism are inseparable: Homologous recombination is essential for completion of DNA replication and vice versa.
Michelle Hawkins +2 more
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GEN1 promotes common fragile site expression
Cell Reports, 2023 Summary: Our genomes harbor conserved DNA sequences, known as common fragile sites (CFSs), that are difficult to replicate and correspond to regions of genome instability.
Anaid Benitez +6 more
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Single-crossover recombination and ancestral recombination trees [PDF]
Journal of Mathematical Biology, 2013 J. Math. Biol., in press.
Baake, Ellen, von Wangenheim, Ute
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λ Recombination and Recombineering
EcoSal Plus, 2016 The bacteriophage λ Red homologous recombination system has been studied over the past 50 years as a model system to define the mechanistic details of how organisms exchange DNA segments that share extended regions of homology. The λ Red system proved useful as a system to study because recombinants could be easily generated by co ...
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Microbiology Spectrum, 2021 Porcine parvovirus genotype 1 (PPV1) causes reproductive disorder in swine and is prevalent in China. Recently, six new genotypes of PPVs (PPV2 through PPV7) have also been detected in Chinese swine herds.
Jixiang Li +8 more
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Journal of Physics G: Nuclear and Particle Physics, 2004 Plenary Talk at Quark Matter 2004, submitted to J. Phys.
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VirusesDuring retrovirus assembly, Gag packages unspliced viral RNA as the virion genome. Genome packaging is usually specific with occasional exceptions of cross-packaging RNA from distantly related retroviruses.
Zetao Cheng +5 more
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