Results 61 to 70 of about 481,827 (299)

Recombination

open access: yes, 2008
Genetic recombination of viruses is a commonly found phenomenon in both DNA and RNA viruses. By exchanging of fragments of genetic material viruses gain important means leading to both variability and also to the repair of their genome. Biochemically, the processes of DNA and RNA recombination are different reflecting the specifics of DNA versus RNA ...
openaire   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Evidence for Strong Fixation Bias at 4-fold Degenerate Sites Across Genes in the Great Tit Genome

open access: yesFrontiers in Ecology and Evolution, 2018
It is well established that GC content varies across the genome in many species and that GC biased gene conversion, one form of meiotic recombination, is likely to contribute to this heterogeneity.
Toni I. Gossmann   +4 more
doaj   +1 more source

Recombination: Pieces of the site-specific recombination puzzle [PDF]

open access: yesCurrent Biology, 1995
Understanding how nucleoprotein complexes interact with specific DNA sequences has come closer with structural and mechanistic studies of the interaction between the recombination enzyme resolvase and DNA.
Stephen E. Halford   +2 more
openaire   +3 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

open access: yesAdvanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang   +5 more
wiley   +1 more source

HIV-1 transcription start sites usage and its impact on unspliced RNA functions in people living with HIV

open access: yesmBio
HIV-1 unspliced RNA serves two distinct functions during viral replication: it is packaged into particles as the viral genome, and it is translated to generate Gag/Gag-Pol polyproteins required for virus assembly. Recent studies have demonstrated that in
Saiful Islam   +7 more
doaj   +1 more source

INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions

open access: yesMolecular Therapy: Methods & Clinical Development, 2017
Analysis of sites of newly integrated DNA in cellular genomes is important to several fields, but methods for analyzing and visualizing these datasets are still under development.
Charles C. Berry   +16 more
doaj   +1 more source

Low‐Activation Compositionally Complex Alloys for Advanced Nuclear Applications—A Review

open access: yesAdvanced Engineering Materials, EarlyView.
Low‐activation compositionally complex alloys (LACCAs) are advanced metallic materials primarily composed of low‐activation elements, offering advantages such as rapid compliance with operational standards and safe recyclability. This review highlights their potential for extreme high‐temperature irradiation environments as structural materials for ...
Yangfan Wang   +8 more
wiley   +1 more source

Porcine Torovirus (PToV)—A Brief Review of Etiology, Diagnostic Assays and Current Epidemiology

open access: yesFrontiers in Veterinary Science, 2019
Porcine torovirus (PToV) is a potential enteric swine pathogen, found at especially high rates in piglets with diarrhea. It was first reported in the Netherlands in 1998 and has emerged in many countries around the world.
Zhang-Min Hu   +5 more
doaj   +1 more source

The Frequency of Sex: Population Genomics Reveals Differences in Recombination and Population Structure of the Aflatoxin-Producing Fungus Aspergillus flavus

open access: yesmBio, 2020
The apparent rarity of sex in many fungal species has raised questions about how much sex is needed to purge deleterious mutations and how differences in frequency of sex impact fungal evolution.
Milton T. Drott   +6 more
doaj   +1 more source

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