Results 71 to 80 of about 631,742 (318)
federlab/hiv-recombination: v1.0.0 - BioRxiv submission
Associated code for Elevated HIV viral load is associated with higher recombination rate in vivo Elena Romero @evromero-uw Alison Feder @affeder https://doi.org/10.1101/2023.05.05 ...
evromero-uw, affeder
core +1 more source
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +4 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
An impact of physical phenomena on admittances of partially-depleted SOI MOSFETs
An in uence of the selected physical phenom- ena: impact ionization in silicon and time variation of inter- nal electric field distribution in partially-depleted (PD) SOI MOSFETs on several C-V characteristics of these devices is presented.
Jan Gibki
doaj +1 more source
Screening and epitope characterization of Nidogen‐2‐specific nanobodies
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Recombination-mediated host-adaptation by avian Staphylococcus aureus
Supplementary tables for 'Recombination-mediated host-adaptation by avian Staphylococcus aureus' by Murray et al. Figure S1: Genetic relatedness of S.
Ben Pascoe (3139548)
core +1 more source
High-resolution genotyping and mapping of recombination and gene conversion in the protozoan Theileria parva using whole genome sequencing [PDF]
BACKGROUND: Theileria parva is a tick-borne protozoan parasite, which causes East Coast Fever, a disease of cattle in sub-Saharan Africa. Like Plasmodium falciparum, the parasite undergoes a transient diploid life-cycle stage in the gut of the arthropod ...
Spooner Paul R +49 more
core +1 more source
AlexKI123/Wright-Fisher-with-recombination: Manuscript code
Code to reproduce the analysis in the manuscript "Conflicting effects of recombination on the evolvability and robustness in neutrally evolving ...
AlexKI123
core +1 more source
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel +8 more
wiley +1 more source

