Results 81 to 90 of about 1,354,525 (383)

Recombination in the Open-Ended Value Landscape of Digital Innovation [PDF]

open access: yes, 2018
Digital innovation introduces a new open-ended value landscape to anyone seeking to generate or capture new value. To understand this landscape, we distinguish between design recombination and use recombination, explore how they play out together, and ...
Arthur   +55 more
core   +2 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

Location and Identification on Chromosome 3B of Bread Wheat of Genes Affecting Chiasma Number

open access: yesPlants, 2022
Understanding meiotic crossover (CO) variation in crops like bread wheat (Triticum aestivum L.) is necessary as COs are essential to create new, original and powerful combinations of genes for traits of agronomical interest.
Benoit Darrier   +7 more
doaj   +1 more source

Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line [PDF]

open access: yes, 1984
We demonstrated that a subclone of an Abelson murine leukemia virus-transformed B-lymphoid cell line switched from mu to gamma 2b expression in vitro, by the classical recombination-deletion mechanism.
Alt, Frederick W.   +5 more
core  

Exciton Recombination in One-Dimensional Organic Mott Insulators

open access: yes, 2015
We present a theory for the recombination of (charged) holons and doublons in one-dimensional organic Mott insulators, which is responsible for the decay of a photoexcited metallic state.
Eckstein, Martin   +2 more
core   +1 more source

Recombination

open access: yes, 2008
Genetic recombination of viruses is a commonly found phenomenon in both DNA and RNA viruses. By exchanging of fragments of genetic material viruses gain important means leading to both variability and also to the repair of their genome. Biochemically, the processes of DNA and RNA recombination are different reflecting the specifics of DNA versus RNA ...
openaire   +1 more source

ClonalFrameML: Efficient Inference of Recombination in Whole Bacterial Genomes

open access: yesPLoS Comput. Biol., 2015
Recombination is an important evolutionary force in bacteria, but it remains challenging to reconstruct the imports that occurred in the ancestry of a genomic sample.
X. Didelot, Daniel J. Wilson
semanticscholar   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

An impact of physical phenomena on admittances of partially-depleted SOI MOSFETs

open access: yesJournal of Telecommunications and Information Technology, 2001
An in uence of the selected physical phenom- ena: impact ionization in silicon and time variation of inter- nal electric field distribution in partially-depleted (PD) SOI MOSFETs on several C-V characteristics of these devices is presented.
Jan Gibki
doaj   +1 more source

Role of Diversity and Recombination in the Emergence of Chilli Leaf Curl Virus

open access: yesPathogens, 2022
Chilli leaf curl virus (ChiLCV), (Genus Begomovirus, family Geminiviridae) and associated satellites pose a serious threat to chilli production, worldwide.
Megha Mishra   +6 more
doaj   +1 more source

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