Results 161 to 170 of about 9,223,247 (288)

A Transcriptionally Distinct Intermediate Activation State Precedes Langerhans Cell Migration From the Epidermis

Advanced Science, EarlyView.
A transcriptionally distinct intermediate Langerhans cell state is identified between steady and migratory populations during skin injury. Integrated single‐cell transcriptomics, flow cytometry, and intravital imaging reveal state‐specific markers and implicate complement signaling, particularly C3, in regulating Langerhans cell accumulation near ...
Artem Kiselev, Axel D. Schmitter‐Sánchez, Sudhanshu Mishra, Hyeri Kim, Sharod Williams, Sangbum Park   +5 more
wiley   +1 more source

Composition‐Aware Cross‐Sectional Integration for Spatial Transcriptomics

Advanced Intelligent Discovery, EarlyView.
Multi‐section spatial transcriptomics demands coherent cell‐type deconvolution, domain detection, and batch correction, yet existing pipelines treat these tasks separately. FUSION unifies them within a composition‐aware latent framework, modeling reads as cell‐type–specific topics and clustering in embedding space.
Qishi Dong, Zijian Huang, Xuanwu Wang, Zhenghui Feng, Wei Liu, Bingding Huang   +5 more
wiley   +1 more source

389 Reconstructed Human Epidermis Colonized with C.acnes: Pro-inflammatory and Oxidative Stress Response [PDF]

, 2022
Francesca Giulia Urso, L. Brambilla, F. Carriero, M. Meloni   +3 more
openalex   +1 more source

Autonomous AI‐Driven Design for Skin Product Formulations

Advanced Intelligent Discovery, EarlyView.
This review presents a comprehensive closed‐loop framework for autonomous skin product formulation design. By integrating artificial intelligence‐driven experiment selection with automated multi‐tiered assays, the approach shifts development from trial‐and‐error to intelligent optimisation.
Yu Zhang, Yongrui Xiao, Chunlin Chen, Dimitrios Tsaoulidis, Kai Yang, Tao Chen   +5 more
wiley   +1 more source

Six‐DoF Strawberry Harvesting Pose Selection and Adaptive Obstacle Clearing in Occluded Environments

Advanced Intelligent Systems, EarlyView.
An occlusion‐aware 6‐DoF harvesting strategy integrates γ‐angle pose selection, ripeness‐weighted risk evaluation, and adaptive obstacle clearing. The approach enables collision‐free grasping orientation selection and improves strawberry harvesting reliability under complex occlusion, achieving higher success rates and reduced fruit damage. In complex,
Tianxiao Zhu, Chunjiang Zhao, Zhonghua Miao, Wei Zhang, Ya Xiong   +4 more
wiley   +1 more source

Beyond the Camera: Epidermal Sensor Platforms for Intelligent Facial Expression Recognition and Interactive Human Monitoring

Advanced Intelligent Systems, EarlyView.
Skin‐conformal epidermal sensors enable camera‐free intelligent facial monitoring by converting facial deformation and muscle activity into electrical signals through piezoresistive, capacitive, electrophysiologic, and self‐powered mechanisms. Coupled with artificial intelligence (AI), these platforms support facial expression recognition, human ...
Jeehyun Joung, Manchi Nagaraju, Jun‐Gyu Choi, Jaeil Park, Sungjun Park, Daegun Kim   +5 more
wiley   +1 more source

Proniosomal Gel for Topical Delivery of Rutin: Preparation, Physicochemical Characterization and In Vitro Toxicological Profile Using 3D Reconstructed Human Epidermis Tissue and 2D Cells. [PDF]

Antioxidants (Basel), 2021
Pinzaru I, Tanase A, Enatescu V, Coricovac D, Bociort F, Marcovici I, Watz C, Vlaia L, Soica C, Dehelean C.   +9 more
europepmc   +1 more source

Reconstructed human epidermis‐based testing strategy of skin sensitization potential and potency classification using epidermal sensitization assay and in silico data

, 2023
Hideyuki Mizumachi, Sho Suzuki, Megumi Sakuma, Midori Natsui, Noriyasu Imai, Masaaki Miyazawa   +5 more
openalex   +1 more source

Hard Water and Cleansers: An In-Vitro Study of the Effects on Immature Reconstructed Human Epidermis

, 2019
Background: Barrier function impairment resulting from increased exposure to daily use of surfactants in the presence of hard water (HW) has been identified as a relevant factor to the development of atopic dermatitis (AD), especially in infants ...
Semenzato Alessandra, Meloni Marisa, Ceriotti Laura, Galizia Giulia, Baratto Gianni   +4 more
core  

Human digital Meissner's corpuscles are not doubly innervated

The Anatomical Record, EarlyView.
Abstract Recent studies have shown that murine and avian Meissner‐like corpuscles are innervated by two distinct mechanoreceptor afferents with different functional properties. In addition, there is evidence that one subpopulation of Meissner corpuscles of monkeys is doubly innervated by mechanoreceptors and nociceptors.
Patricia Cuendias, Yolanda García‐Mesa, Iván Suazo, Marta Alonso‐Guervós, Jorge García‐Piqueras, Ana M. Abreu‐Velez, Olivia García‐Suárez, Jorge Feito, José A. Vega   +8 more
wiley   +1 more source