Results 221 to 230 of about 9,223,247 (288)
Ion Activation Methods for Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley +1 more source
Organoid Coculture Models for Cancer Research and Immunotherapy
Med Research, EarlyView.This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang +9 more
wiley +1 more source
National Materials, EarlyView.In this study, we engineered an antibacterial, antioxidative and epidermal grow factor‐encapsulated multifunctional hydrogel for the repair of chronic and refractory wounds. The hydrogel markedly promoted wound healing in rat models of diabetic foot ulcers and infected wounds by modulating wound microenvironment.
Zheng Zou +5 more
wiley +1 more source
The Journal of Pathology, EarlyView.Abstract TP53 is the most frequently mutated gene in oral squamous cell carcinoma (OSCC); however, its role in promoting epithelial–mesenchymal transition (EMT) and tumour progression remains unclear, particularly within the context of intra‐tumour heterogeneity.
Rana Alaaeldin Ibrahim +9 more
wiley +1 more source
Treg‐stromal cell axis in tissue repair and autoimmune diseases: Mechanisms and clinical translation
Rheumatology &Autoimmunity, EarlyView.The Treg‐stromal cell axis as a central regulator of tissue repair and immune tolerance. Under physiological conditions, bidirectional communication between Tregs and stromal cells—mediated by cell‐surface molecular contacts, anti‐inflammatory cytokines, and extracellular vesicles—orchestrates inflammation resolution, immune tolerance, and complete ...
Peiyan Zhang +2 more
wiley +1 more source
Detection and Potency Classification of Pre- and Pro-Haptens Using the SENS-IS Assay: The Role of Metabolically Competent Reconstructed Skin. [PDF]
ToxicsCottrez F +5 more
europepmc +1 more source
Responsive Materials, EarlyView.Guided by the spectral demand of plant photosystems, this review summarizes the synthesis, emission regulation, dual‐emission design, and gram‐scale production of CDs for agricultural applications. Spectrally matched blue‐ and red‐emissive CDs enhance plant light utilization by converting underutilized light into photosynthetically active radiation and
Yijing Chen +5 more
wiley +1 more source
Responsive Materials, EarlyView.A MXene‐doped conductive elastomer was engineered via a dynamic disulfide‐bonded network supramolecularly reinforced by reversible hydrogen‐bonding crosslinks, affording robust mechanical performance, autonomous self‐healing, and biocompatibility suited to strain sensing across dual environments.
Fang‐Yu Liu +3 more
wiley +1 more source
Barrier model selection alters apparent diclofenac permeation parameters: a controlled <i>in vitro</i> comparison of Strat-M<sup>®</sup> and a HaCaT-based epidermal construct. [PDF]
Front PharmacolDugonik F +6 more
europepmc +1 more source