Results 241 to 250 of about 9,223,247 (288)

Magnetothermal‐responsive drug release bone cement based on EGFR‐mutated lung cancer bone metastases

VIEW, EarlyView.
A novel magnetothermal‐responsive bone cement was developed by integrating PMMA/CPC/Osimertinib matrix with Fe3O4@SiO2@Zol nanomaterials. This dual‐drug system achieves controlled release, combining excellent mechanical properties with potent anti‐tumor activity and bone regulation for treating EGFR‐mutated LC‐BoM.
Kandi Xu, Kai Li, Hao Wang, Lishu Zhao, Xinyue Liu, Yujin Liu, Li Ye, Wengang Zhang, Zhimin Chen, Xuyang Chen, Yujie Li, Qianqian Zhang, Wencheng Zhao, Xuebin Zheng, Yu Chen, Yayi He   +15 more
wiley   +1 more source

Plant‐derived nanovesicles as potential drug delivery systems for topical use: Emerging applications in dermatology and cosmetology

VIEW, EarlyView.
Plant‐derived nanovesicles (PDNVs) are naturally secreted by fruit, vegetables, seeds, leaves and other natural sources. Used as drug delivery systems, they can combine intrinsic therapeutic activity, enhanced skin permeation and cargo‐carrying capacity, suitable for dermatological and cosmetic applications including hydration, antioxidant/anti ...
Dorotea Fiore, Beatrice Pellegrini, Antonia Mancuso, Maria Chiara Cristiano, Salvatore Panza, Donatella Paolino   +5 more
wiley   +1 more source

TRPV4 mediates low-humidity responses in epidermal keratinocytes. [PDF]

Proc Natl Acad Sci U S A
Tanaka M, Chikuma S, Hara-Chikuma M.
europepmc   +1 more source

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno-Free Culture Systems. [PDF]

Adv Healthc Mater
Lemaître G, Trouillas M, Vinasco-Sandoval T, Giordano C, Lellouch AG, Rachidi W, Lataillade JJ, Fortunel NO.   +7 more
europepmc   +1 more source

Biologically engineered vectors enable topical mRNA delivery for skin regeneration. [PDF]

Commun Biol
Gérard J, Pilet H, Bouez C, Du X, Chen Y, Kalia YN, Clayette P, Bernard BA, Grandchamp N.   +8 more
europepmc   +1 more source

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Impaired Desquamation in the in Vitro Reconstructed Human Epidermis

Cell and Tissue Research, 1996
A fully differentiated epidermis generated in vitro by culturing normal human keratinocytes at the air-liquid interface shares many similarities with native tissue. However, in contrast to native epidermis, its stratum corneum consists of a larger number of compactly packed corneocyte layers, indicating that the processes involved in corneocyte ...
Aat A Mulder, Jana Vicanova, Maria Ponec
exaly   +3 more sources

The Use of Reconstructed Human Epidermis for Skin Absorption Testing: Results of the Validation Study

ATLA Alternatives To Laboratory Animals, 2008
A formal validation study was performed, in order to investigate whether the commercially available reconstructed human epidermis (RHE) models, EPISKIN®, EpiDermT and SkinEthic®, are suitable for in vitro skin absorption testing.
Monika Schäfer-Korting, Manfred Liebsch, Claus-Michael Lehr   +2 more
exaly   +1 more source