Results 41 to 50 of about 168,205 (293)

RhoA and Rac1 as Mechanotransduction Mediators in Colorectal Cancer

Advanced Biology, EarlyView.
Analysing RhoA and Rac1 protein levels in Colorectal cancer (CRC) samples under mechanical strain highlights their potential as diagnostic markers. Monitoring their activity could offer valuable insights into how cancer spreads, paving the way for new approaches to better understand and diagnose colorectal cancer.
Sharda Yadav, Sanjaya KC, Mark A. T. Blaskovich, Cu‐tai Lu, Alfred K Lam, Nam‐Trung Nguyen   +5 more
wiley   +1 more source

Lavage cytology diagnosed by immunostaining may be a poor prognostic factor in pathological stage III colorectal cancer

Annals of Gastroenterological Surgery
Aim To clarify the prognostic impact of positive lavage cytology diagnosed by immunostaining on long‐term outcomes following curative resection for pathological stage III colorectal cancer (CRC).
Akitoshi Nankaku, Yusuke Yamaoka, Akio Shiomi, Hiroyasu Kagawa, Shoichi Manabe, Takuma Oishi, Kiyoshi Tone, Akifumi Notsu, Yusuke Kinugasa   +8 more
doaj   +1 more source

Patient delay in colorectal cancer patients: associations with rectal bleeding and thoughts about cancer.

PLoS ONE, 2013
Rectal bleeding is considered to be an alarm symptom of colorectal cancer. However, the symptom is seldom reported to the general practitioner and it is often assumed that patients assign the rectal bleeding to benign conditions.
Anette F Pedersen, Rikke P Hansen, Peter Vedsted   +2 more
doaj   +1 more source

Biologically‐Inspired Melt Electrowriting for the Generation of Highly Biomimetic Functional Myocardium

Advanced Functional Materials, EarlyView.
In this work, melt electrowriting is used to fabricate a 3D printed scaffold design that generates engineered cardiac tissues with in‐plane contraction, mimicking natural myocardium. It is shown that these tissues display advanced maturation and functionality.
Olalla Iglesias‐García, María Flandes‐Iparraguirre, Pilar Montero‐Calle, Ricardo M. Rosales, Asier Ullate‐Agote, Andrea Sánchez‐Bueno, Eduardo Larequi, Ilazki Anaut‐Lusar, Nicolás Laita, Aida Oliván‐Viguera, Elena Iglesias, Gloria Abizanda, Patxi San Martín‐Úriz, Paula Aguirre‐Ruiz, Xabier L. Aranguren, Manuel García de Yébenes, Juan José Gavira, Miguel Ángel Martínez, Estefanía Peña, Manuel Doblaré, Elena M. de‐Juan‐Pardo, Esther Pueyo, Felipe Prosper, Manuel M. Mazo Vega   +23 more
wiley   +1 more source

Testing Machine Learning Models to Predict Postoperative Ileus after Colorectal Surgery

Current Oncology
Background: Postoperative ileus (POI) is a common complication after colorectal surgery, leading to increased hospital stay and costs. This study aimed to explore patient comorbidities that contribute to the development of POI in the colorectal surgical ...
Garry Brydges, George J. Chang, Tong J. Gan, Tsuyoshi Konishi, Vijaya Gottumukkala, Abhineet Uppal   +5 more
doaj   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Identifications of Candidate Genes Significantly Associated With Rectal Cancer by Integrated Bioinformatics Analysis

Technology in Cancer Research & Treatment, 2020
Introduction: Rectal cancer ranks as the eighth in cancer-related morbidity and the tenth in the cancer-related mortality. A few studies have explored several biomarkers for colorectal cancer. However, there is still a great need for us to excavate novel
Zhili Xu PhD, Yan Li PhD, Yiyi Cui, Yong Guo PhD   +3 more
doaj   +1 more source

Research on radiotherapy related genes and prognostic target identification of rectal cancer based on multi-omics

Journal of Translational Medicine, 2023
Background Radiosensitivity of rectal cancer is related to the radiotherapy efficacy and prognosis of patients with rectal cancer, and the genes and molecular mechanisms related to radiosensitivity of rectal cancer have not been clarified.
Yi Liu, Yanguang Yang, Feng Ni, Guomei Tai, Cenming Yu, Xiaohui Jiang, Ding Wang   +6 more
doaj   +1 more source

CHEMOTHERAPY IN RECTAL CANCER

Wiadomości Lekarskie, 2021
The aim: To evaluate and analyze early and late results of treatment of patients with rectal cancer after chemotherapy. Materials and methods: The study is based on the results of observation of 779 patients with stage II, III and IV rectal cancer (RC) who were divided into groups according to the chemotherapy treatment.
Anna Kryzhanivska, Volodymyr Holotiuk, Olha Ivantsіv, Alina Andriiv, B. B. Tataryn   +4 more
openaire   +3 more sources

Stretchable, Multiplexed, and Bimodal Sensing Electronic Armor for Colonoscopic Continuum Robot Enhanced by Triboelectric Artificial Synapse

Advanced Materials, EarlyView.
Colonoscopic continuum robots lack sensing, endangering intestinal tissue. An ideal sensing array is hard to integrate. This work introduces a 3D crosslinked stretchable E‐armor with full‐coverage and multiplexing. It has bimodal sensing, forms a triboelectric synapse, uses CNN‐LSTM, and has a hydrogel and innovative triboelectric materials.
Yuyang Sun, Tao Chen, Dongsheng Li, Hanyang Li, Tianci Ji, Fengxia Wang, Lining Sun, Chengkuo Lee, Huicong Liu   +8 more
wiley   +1 more source