Results 81 to 90 of about 225,683 (335)

Microglial Fkbp5 Impairs Post‐Stroke Vascular Integrity and Regeneration by Promoting Yap1‐Mediated Glycolysis and Oxidative Phosphorylation

Advanced Science, EarlyView.
A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li, Yanmei Qiu, Yunlei Yang, Yanhao Wei, Haokun Peng, Longhai Zeng, Pengcheng Li, Rentang Bi, Bo Hu   +8 more
wiley   +1 more source

Solitary rectal ulcer syndrome: MRI findings and differentiation from rectal cancer

Insights into Imaging
Background Systematic MRI findings of solitary rectal ulcer syndrome (SRUS) are lacking. We aimed to evaluate the MRI findings of SRUS and to identify the MRI features that differentiate SRUS from rectal cancer.
Peiyi Xie, Xiaoying Lou, Shuai Fu, Xiaohui Di, Qitong Huang, Zhiming Zeng, Kexin Niu, Junying Zhu, Meiyu Hu, Xiaochun Meng   +9 more
doaj   +1 more source

MRI in local staging of rectal cancer: an update

Diagnostic and Interventional Radiology, 2014
Preoperative imaging for staging of rectal cancer has become an important aspect of current approach to rectal cancer management, because it helps to select suitable patients for neoadjuvant chemoradiotherapy and determine the appropriate surgical ...
Ümit Tapan, Mustafa Özbayrak, Servet Tatlı   +2 more
doaj   +1 more source

Presence and persistence of Ebola or Marburg virus in patients and survivors: A rapid systematic review [PDF]

, 2016
Background: The 2013-15 Ebola outbreak was unprecedented due to sustainedtransmission within urban environments and thousands of survivors. In 2014 the World Health Organization stated that there was insufficient evidence to give definitive guidance ...
Brainard, Julii, Edmunds, Kelly, Hooper, Lee, Hunter, Paul, Pond, Katherine   +4 more
core   +3 more sources

NAD+‐Dependent Enzyme SIRT3 Limits Intestinal Epithelial Cell Functions Through NAD+ Synthesis Pathway in Colorectal Cancer

Advanced Science, EarlyView.
Microbiota‐derived quinolinic acid is used as an alternative source of replenishing the intracellular NAD+ pool induced by SIRT3 deficiency to regulate intestinal epithelial cell and T cell function, which has implications for targeting intestinal epithelial cells as an approach to the treatment of immune‐associated diseases, including colorectal ...
Ruiying Niu, Yingjie Dong, Jianghui Tong, Jingxuan Xia, Longhao Zhao, Zi Geng, Yingxin Lin, Jinghe Zhang, Xinyi Liu, Manqi Fang, Xi Jin, Yujing Bi, Guangwei Liu   +12 more
wiley   +1 more source

Surgical Treatment of Rectal Prolapse (History of the Issue and Modern Perspective — Literature Review)

Российский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: to assess the data on the most common surgical interventions for rectal prolapse.Key points. At present, there are more than 100 methods of surgical correction of rectal prolapse that are carried out by means of the perineal or abdominal approach ...
O. M. Biryukov, A. A. Mudrov, A. Yu. Titov, I. V. Kostarev, A. S. Lukianov, E. E. Zharkov, T. Yu. Shavrina, S. I. Achkasov   +7 more
doaj   +1 more source

Conservative treatment of hemorrhoids: focus on combination tribenoside and lidocaine

Амбулаторная хирургия, 2019
Hemorrhoidal  disease  has been  known since  ancient  times  and remains  one of the  most  common human  diseases. This review presents the results  of tribenoside and lidocaine combinations used in the conservative therapy of hemorrhoids, which give ...
D. I. Trukhan, E. N. Degovtsov, L. V. Belkina   +2 more
doaj   +1 more source

Genetically‐Programmed Hypervesiculation of Lactiplantibacillus Plantarum Increases Production of Bacterial Extracellular Vesicles with Therapeutic Efficacy in a Preclinical Inflammatory Bowel Disease Model

Advanced Science, EarlyView.
The development of a novel engineered strain of Lactiplantibacillus plantarum (Lp) is reported that can produce bacterial extracellular vesicles (BEVs) at >60‐fold higher yields than the unmodified parental strain. These Lp BEVs retain therapeutic bioactivity as validated in a mouse model of dextran sodium sulfate‐induced colitis.
Nicholas H Pirolli, Daniel Levy, Alyssa Schledwitz, Natalia Sampaio Moura, Mitali Sarkar, Talia J. Solomon, Emily H. Powsner, Raith Nowak, Zuzanna Mamczarz, Christopher J. Bridgeman, Sulayman Khan, Andrew Hui, Nidhi Anne, Laura Reus, William E. Bentley, Jean‐Pierre Raufman, Steven M. Jay   +16 more
wiley   +1 more source

Rectal Syphilis Mimicking Malignancy: A Case Report

Journal of the Korean Society of Radiology
Rectal syphilis is a rare form of syphilis presentation and its symptoms, endoscopic and radiologic findings are nonspecific. Rectal syphilis typically presents with features such as concentric rectal wall thickening, mucosal hyperemia, perirectal fat ...
Sunjin Ryu, Bo-Kyeong Kang, Mimi Kim, Chul-Min Lee   +3 more
doaj   +1 more source

Environmental pollutants and rectal cancer: The impact of water contamination

Ecotoxicology and Environmental Safety
Background: Water is a fundamental resource for life, and exposure to water contamination has far-reaching implications for an increased risk of tumor diseases.
Yezhou Li, Zhe Piao, Xinbin Ge, Jinbao Feng, Denghua Sun, Jiayu Zhang   +5 more
doaj   +1 more source