Results 231 to 240 of about 40,681 (284)

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

Advanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo, Naifeng Zhu, Zhuocheng Lyu, Yifei Liu, Zhenjiang Xu, Chun Zhou, Yaochao Zhao, Changgui Shi   +7 more
wiley   +1 more source

Molecular subtype of recurrent implantation failure reveals distinct endometrial etiology of female infertility. [PDF]

J Transl Med
Yang J, Yang L, Zhou Y, Cao F, Fang H, Ma H, Ren J, Huang C, Diao L, Li Q, Chen Q.   +10 more
europepmc   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

Advanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng, Chao He, Zhibin He, Hongbo Chen, Fang Cheng, Yongjiang Zheng   +5 more
wiley   +1 more source

Anxiety and depression in recurrent implantation failure after frozen-thawed embryo transfer and efficacy of endometrial receptivity testing. [PDF]

World J Psychiatry
Guo YB, Tang B, Zhang L, Wu X, Huang ZH.
europepmc   +1 more source

Mechanistic Insights Into Recurrent Implantation Failure: The Lactate-H3K18la-SLC7A11 Axis Explored via Endometrial Organoid and Blastoid-Endometrial Cell Implantation Models. [PDF]

Cell Prolif
Dong L, Sun X, An S, Xiang J, Hu L, Yao D, Chang J, Jia R, Yang Y, Wang S.   +9 more
europepmc   +1 more source

Expert Opinion: Place in Therapy of Probiotics in Infertility and Recurrent Implantation Failure. [PDF]

Cureus
Patki A, Kar S, Patel N, Ingale K, Bansal K, Durga P.   +5 more
europepmc   +1 more source

Does Developmental Timing Matter? Comparative Analysis of Day 5 and Day 6 Euploid Blastocyst Transfers in Recurrent Implantation Failure Patients. [PDF]

Biomedicines
Şişmanoğlu A, Oğlak SC, Atayurt Z, Gökdağlı Sağır F, Uluğ U.   +4 more
europepmc   +1 more source

Endometrial Steroid Receptor Dysregulation and Its Association with Vitamin D, AMH, and Inflammation in Recurrent Implantation Failure: A Case-Control Study. [PDF]

Int J Fertil Steril
Rostami R, Jahanbakhsh J, Mahdinia E, Rezaei A, Yarahmadi S, Omodiani N, Tehranian A, Fallah S.   +7 more
europepmc   +1 more source

Impact of platelet-rich plasma intrauterine perfusion on endometrial receptivity and pregnancy outcomes in patients with recurrent implantation failure and thin endometrium. [PDF]

Am J Transl Res
Peng F, Xia M, Zheng J, Wang X, Liu J, Sun H.   +5 more
europepmc   +1 more source

Molecular Determinants of Uterine Receptivity: Comparison of Successful Implantation, Recurrent Miscarriage, and Recurrent Implantation Failure [PDF]

International Journal of Molecular Sciences, 2023
Embryo implantation is one of the most remarkable phenomena in human reproduction and is not yet fully understood. Proper endometrial function as well as a dynamic interaction between the endometrium itself and the blastocyst—the so-called embryo ...
Leila Allahqoli, Anupama Deenadayal-Mettler, Georgios Gitas   +2 more
exaly   +2 more sources