A simulation framework for reciprocal recurrent selection-based hybrid breeding under transparent and opaque simulators. [PDF]
Front Plant Sci, 2023 Zhang Z, Wang L.
europepmc +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Recurrent selection and reduction in recombination shape the genomic landscape of divergence across multiple population pairs of Green-backed Tit. [PDF]
Evol Lett, 2023 Jiang Z +5 more
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Managerial Talent, Motivation, and Self-Selection into Public Management [PDF]
The quality of public management is a recurrent concern in many countries. Calls to attract the economy’s best and brightest managers to the public sector abound.
Josse Delfgaauw, Robert Dur
core +3 more sources
Revista Ceres, 2012 Os objetivos deste trabalho foram verificar a acurácia do método da Seleção Genômica Ampla (GWS) no melhoramento de milho nas condições de estresse nutricional e propor novos métodos de melhoramento baseados em GWS. Foram estimados os dois componentes da
Roberto Fritsche-Neto +3 more
doaj
Selection index and molecular markers in reciprocal recurrent selection in maize. [PDF]
, 2018 Reciprocal recurrent selection among full-sib families is one of the outstanding methodologies of maize improvement. since gains are possible in the per se and/or in cross population.
AMARAL JÚNIOR, A. T. do +4 more
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Marker-Assisted Recurrent Selection for Pyramiding Leaf Rust and Coffee Berry Disease Resistance Alleles in Coffea arabica L. [PDF]
Genes (Basel), 2023 Saavedra LM +8 more
europepmc +1 more source
An uncued brain-computer interface using reservoir computing [PDF]
, 2010 Brain-Computer Interfaces are an important and promising avenue for possible next-generation assistive devices. In this article, we show how Reservoir Comput- ing – a computationally efficient way of training recurrent neural networks – com- bined with a
Buteneers, Pieter +3 more
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