Results 151 to 160 of about 347,214 (307)
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Evaluation of recurrent selection in Leaming and Midland maize populations
, 1999 Rates of maize (Zea mays L.) yield improvement in the United States has been reduced during the 1990's. Double-cycle breeding in a few old inbred lines and limited germplasm evaluation and utilization are possible explanations. Only one heterotic pattern
Carena, Marcelo
core +1 more source
Viability of the UENF popcorn improvement program based on divergence in S1 families
Crop Breeding and Applied Biotechnology, 2005 With the objective of evaluating the viability of the program of recurrent selection with popcorn of the Universidade Estadual do Norte Fluminense Darcy Ribeiro carried out in Campos dos Goytacazes and Itaocara, state of Rio de Janeiro, 40 families that ...
Antonio Teixeira do Amaral Júnior +5 more
doaj
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Selection aiming at upright growth habit common bean with carioca type grains
Crop Breeding and Applied Biotechnology, 2005 Aiming at common bean lines with a high grain yield, upright growth habit and carioca type grains, ten common bean lines were crossed in a diallel scheme. The resulting populations were evaluated as to their capacity of generating superior lines.
Welcimar Gonçalves da Cunha +2 more
doaj
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Estimation of genetic variance in reciprocal recurrent selection corn composites
, 1970 This study was undertaken to evaluate the genetic variance and the genetic behavior of each of twelve corn composites developed in a reciprocal recurrent selection program.
Chicco, Giuseppe
core
Frontiers in Plant ScienceHeterosis is an important approach to improving wheat yield and quality. Previously, five recurrent selection populations were established to broaden genetic diversity via a recurrent selection strategy using French wheat, Spelt wheat, spike-branched ...
Ziyan Wu +9 more
doaj +1 more source
Which Recurrent Selection Scheme To Improve Mixtures of Crop Species? Theoretical Expectations. [PDF]
G3 (Bethesda), 2020 Sampoux JP, Giraud H, Litrico I.
europepmc +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source