RecX facilitates homologous recombination by modulating RecA activities.
PLoS Genetics, 2012 The Bacillus subtilis recH342 strain, which decreases interspecies recombination without significantly affecting the frequency of transformation with homogamic DNA, carried a point mutation in the putative recX (yfhG) gene, and the mutation was renamed ...
Paula P Cárdenas +7 more
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The RecX protein interacts with the RecA protein and modulates its activity in Herbaspirillum seropedicae [PDF]
Brazilian Journal of Medical and Biological Research, 2012 DNA repair is crucial to the survival of all organisms. The bacterial RecA protein is a central component in the SOS response and in recombinational and SOS DNA repairs.
C.W. Galvão +8 more
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Escherichia coli recombinant sperm immobilizing factor RecX as a potential vaginal contraceptive [PDF]
Reproductive Biology and Endocrinology, 2018 Background To control the overpopulation and unintended pregnancies, vaginal contraceptives have gained recent surge of interest because of its topical application with possible avoidance of systemic effects.
Monika Answal, Vijay Prabha
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The Role of RecX in Mycobacteria [PDF]
, 2010 Tuberculosis is a major global public health problem which causes millions of deaths every year. It is caused by the bacterium Mycobacterium tuberculosis, which survives and replicates within host macrophages, in which it has to overcome the effects of various DNA damaging agents in order to survive.
Manglani, Sapna Lakhi
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Elucidating the functional role of Mycobacterium smegmatis recX in stress response [PDF]
Scientific Reports, 2019 AbstractThe RecX protein has attracted considerable interest because therecXmutants exhibit multiple phenotypes associated with RecA functions. To further our understanding of the functional relationship betweenrecAandrecX, the effect of different stress treatments on their expression profiles, cell yield and viability were investigated.
Prasad, Deepika +3 more
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Proceedings of the 20th ACM International Conference on Computing Frontiers, 2023 Accepted at 20th ACM International Conference on Computing ...
Nikhil Pratap Ghanathe, Steve Wilton
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Directed Evolution of RecA Variants with Enhanced Capacity for Conjugational Recombination. [PDF]
PLoS Genetics, 2015 The recombination activity of Escherichia coli (E. coli) RecA protein reflects an evolutionary balance between the positive and potentially deleterious effects of recombination. We have perturbed that balance, generating RecA variants exhibiting improved
Taejin Kim +5 more
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Differential requirements of two recA mutants for constitutive SOS expression in Escherichia coli K-12. [PDF]
PLoS ONE, 2008 Repairing DNA damage begins with its detection and is often followed by elicitation of a cellular response. In E. coli, RecA polymerizes on ssDNA produced after DNA damage and induces the SOS Response.
Jarukit Edward Long +3 more
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Mechanical force antagonizes the inhibitory effects of RecX on RecA filament formation in Mycobacterium tuberculosis [PDF]
Nucleic Acids Research, 2014 Efficient bacterial recombinational DNA repair involves rapid cycles of RecA filament assembly and disassembly. The RecX protein plays a crucial inhibitory role in RecA filament formation and stability. As the broken ends of DNA are tethered during homologous search, RecA filaments assembled at the ends are likely subject to force.
Le, Shimin +6 more
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DNA Metabolism in Balance: Rapid Loss of a RecA-Based Hyperrec Phenotype. [PDF]
PLoS ONE, 2016 The RecA recombinase of Escherichia coli has not evolved to optimally promote DNA pairing and strand exchange, the key processes of recombinational DNA repair.
Irina V Bakhlanova +5 more
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