Results 101 to 110 of about 522,391 (291)

Spatial variations and precise location of substantia nigra hyperechogenicity in Parkinson’s disease using TCS-MR fusion imaging

npj Parkinson's Disease
Substantia nigra hyperechogenicity (SNH) assessed by transcranial sonography (TCS) is a neuroimaging biomarker of Parkinson’s disease (PD), but its actual location and spatial changes are poorly understood.
Chao Hou, Wei Zhang, Hong-Bing Li, Shuo Li, Fang Nie, Xue-Mei Wang, Wen He   +6 more
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

The interstitial system of the trigeminal spinal tract projects to the red nucleus in mice

, 2007
We studied projections from the interstitial system of the spinal trigeminal tract (InSy-S5T) to the red nucleus of the mouse with retrograde tracers (fluorogold and latex microbeads impregnated with rhodamine and fluorescein).
Souccar, Caden [UNIFESP], Olyntho-Tokunaga, Heloisa Helena Vieira [UNIFESP], Schoorlemmer, Gerhardus Hermanus Maria [UNIFESP], Pinto, Magali Luci [UNIFESP], Lapa, Rita de Cassia Ribeiro da Silva [UNIFESP]   +4 more
core   +1 more source

Pattern Clustering of Symmetric Regional Cerebral Edema on Brain MRI in Patients with Hepatic Encephalopathy

Journal of the Korean Society of Radiology
Purpose Metabolic abnormalities in hepatic encephalopathy (HE) cause brain edema or demyelinating disease, resulting in symmetric regional cerebral edema (SRCE) on MRI.
Chun Geun Lim, Hui Joong Lee
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

SUGAR GLIDER (PETAURUS BREVICEPS) BEHAVIOR IN RED VS BLUE LIGHTING

, 2021
Sugar gliders are an exotic pet that is increasing in popularity in households as well as in zoos. One challenge that caregivers have to manage is their nocturnal circadian rhythm.
Hillman, Elisa
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

The role of the cell nucleus in morphogenesis

, 1966
info:eu-repo/semantics ...
Brachet, Jean
core  

Red nucleus

, 2009
Jeremy Jones, Robab Ghorban Pour, Yuranga Weerakkody   +2 more
  +4 more sources

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source