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Redox Regulation and Noncoding RNAs

Antioxidants & Redox Signaling, 2018
RNA is a heterogeneous class of molecules with the minority being protein coding. Noncoding RNAs (ncRNAs) are involved in translation and epigenetic control mechanisms of gene expression. Recent Advances: In recent years, the number of identified ncRNAs has dramatically increased and it is now clear that ncRNAs provide a complex layer of differential ...
Matthias S, Leisegang   +2 more
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Redox regulation of transcriptional activators

Free Radical Biology and Medicine, 1996
Transcription factors/activators are a group of proteins that bind to specific consensus sequences (cis elements) in the promoter regions of downstream target/effector genes and transactivate or repress effector gene expression. The up- or downregulation of effector genes will ultimately lead to many biological changes such as proliferation, growth ...
Y, Sun, L W, Oberley
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Redox Regulation of the Microcirculation

Comprehensive Physiology, 2020
AbstractThe microcirculation maintains tissue homeostasis through local regulation of blood flow and oxygen delivery. Perturbations in microvascular function are characteristic of several diseases and may be early indicators of pathological changes in the cardiovascular system and in parenchymal tissue function.
Andrew O, Kadlec, David D, Gutterman
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Redox regulation of chlorophyll biosynthesis

Phytochemistry, 2010
Chlorophyll captures and redirects light-energy and is thus essential for photosynthetic organisms. The demand for chlorophyll differs throughout the day and night and in response to changing light conditions. Moreover, the chlorophyll biosynthesis pathway is up to certain points shared between the different tetrapyrroles; chlorophyll, heme, siroheme ...
Stenbæk, Anne, Jensen, Poul Erik
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Redox regulation of phosphatase function

Biochemical Society Transactions, 2004
Although reactive oxygen species play important roles in cellular physiology as signalling molecules, their molecular targets are largely unknown. A probable group of targets for mediating many of the effects of reactive oxygen species on cell signalling is the large diverse family of cysteine-dependent phosphatases, which includes the protein tyrosine
N R, Leslie   +3 more
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Redox Regulation of Copper–Metallothionein

Archives of Biochemistry and Biophysics, 1999
Copper (Cu) is an essential element whose localization within cells must be carefully controlled to avoid Cu-dependent redox cycling. Metallothioneins (MTs) are cysteine-rich metal-binding proteins that exert cytoprotective effects during metal exposure and oxidative stress.
J P, Fabisiak   +7 more
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Redox regulation of TNF signaling

BioFactors, 1999
AbstractTNF is produced during inflammation and induces, among other activities, cell death in sensitive tumour cells. We previously reported an increased generation of ROS in TNF‐treated L929 fibrosarcoma cells prior to cell death. These ROS are of mitochondrial origin and participate in the cell death process.
V, Goossens   +7 more
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Redox Regulation of Neutrophil Function

Antioxidants & Redox Signaling, 2002
ONE could be forgiven for thinking of neutrophils as simple phagocytic cells, useful remnants of a primitive immune system, with their sole function restricted to waste disposal at inflammatory sites. When needed, they are attracted from the circulation by a scent of chemotactic factors generated by cells under assault, and upon arrival they engulf and
Mark B, Hampton   +1 more
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Redox Regulation of Neutrophil Apoptosis

Antioxidants & Redox Signaling, 2002
The persistence of a neutrophil-mediated inflammatory response is due in part to a delay in their spontaneous rates of apoptosis or cell death. Regulating apoptosis has important implications for the resolution of inflammatory disorders, such as the systemic inflammatory response syndrome or acute respiratory distress syndrome.
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Redox Regulation of Chloroplast Transcription

Antioxidants & Redox Signaling, 2003
Chloroplasts are the important plant cell organelles where photosynthesis takes place. Throughout this process, reaction center proteins are degraded and subsequently replenished by redox-responsive gene expression. In addition to well defined posttranscriptional mechanisms at the RNA and protein level, the transcription of chloroplast DNA into RNA ...
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