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Redox regulation of protein kinases
Critical Reviews in Biochemistry and Molecular Biology, 2013Reactive oxygen species (ROS) have been long regarded as by‐products of a cascade of reactions stemming from cellular oxygen metabolism, which, if they accumulate to toxic levels, can have detrimental effects on cellular biomolecules. However, more recently, the recognition of ROS as mediators of cellular communications has led to their classification ...
Kate Carroll
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Redox Regulation and Noncoding RNAs
Antioxidants & Redox Signaling, 2018RNA is a heterogeneous class of molecules with the minority being protein coding. Noncoding RNAs (ncRNAs) are involved in translation and epigenetic control mechanisms of gene expression. Recent Advances: In recent years, the number of identified ncRNAs has dramatically increased and it is now clear that ncRNAs provide a complex layer of differential ...
Matthias S, Leisegang +2 more
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Redox Regulation of Cellular Signalling
Cellular Signalling, 1999Extracellular stimuli elicit a variety of responses, such as cell proliferation and differentiation, through the cellular signalling system. Binding of growth factors to the respective receptor leads to the activation of receptor tyrosine kinases, which in turn stimulate downstream signalling systems such as mitogen-activated protein (MAP) kinases ...
H, Kamata, H, Hirata
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Redox regulation of vascular remodeling
Cellular and Molecular Life Sciences, 2015Vascular remodeling is a dynamic process of structural and functional changes in response to biochemical and biomechanical signals in a complex in vivo milieu. While inherently adaptive, dysregulation leads to maladaptive remodeling. Reactive oxygen species participate in homeostatic cell signaling in tightly regulated- and compartmentalized cellular ...
Keyvan, Karimi Galougahi +2 more
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Redox regulation of skeletal muscle
IUBMB Life, 2008AbstractThe potential deleterious roles of “oxidative stress” have been studied in skeletal muscle for over 30 years, but recent studies have identified that reactive oxygen species and nitric oxide generated by skeletal muscle can exert regulatory roles in cell signalling processes.
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Redox Regulation of the Glucocorticoid Receptor
Antioxidants & Redox Signaling, 1999Redox regulation is currently considered as a mode of signal transduction for coordinated regulation of a variety of cellular processes. The transcriptional regulation of gene expression is also influenced by cellular redox state, most possibly through the oxido-reductive modification of transcription factors.
H, Tanaka +5 more
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Redox regulation of intercellular transport
Protoplasma, 2010Plant cells communicate with each other via plasmodesmata (PDs) in order to orchestrate specific responses to environmental and developmental cues. At the same time, environmental signals regulate this communication by promoting changes in PD structure that modify symplastic permeability and, in extreme cases, isolate damaged cells.
Yoselin, Benitez-Alfonso +2 more
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Fundamentals of redox regulation in biology
Nature Reviews Molecular Cell BiologyOxidation-reduction (redox) reactions are central to the existence of life. Reactive species of oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular processes. Yet, excessive levels of oxidants are associated with ageing and many diseases, including cardiological and neurodegenerative diseases, and cancer.
Helmut Sies +2 more
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Redox-Regulated Mechanisms in Asthma
Antioxidants & Redox Signaling, 2008Homeostasis of the reduction–oxidation (redox) state is critical to protection from oxidative stress in the lungs. Therefore, the lungs have high levels of antioxidants, including glutathione, heme oxygenase, and superoxide dismutase.
Tomoaki, Hoshino +5 more
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Redox Regulation of Chloroplast Transcription
Antioxidants & Redox Signaling, 2003Chloroplasts are the important plant cell organelles where photosynthesis takes place. Throughout this process, reaction center proteins are degraded and subsequently replenished by redox-responsive gene expression. In addition to well defined posttranscriptional mechanisms at the RNA and protein level, the transcription of chloroplast DNA into RNA ...
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