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Fundamentals of redox regulation in biology

Nature Reviews Molecular Cell Biology
Oxidation-reduction (redox) reactions are central to the existence of life. Reactive species of oxygen, nitrogen and sulfur mediate redox control of a wide range of essential cellular processes. Yet, excessive levels of oxidants are associated with ageing and many diseases, including cardiological and neurodegenerative diseases, and cancer.
Helmut Sies   +2 more
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Redox regulation of cyclophilin A by glutathionylation

PROTEOMICS, 2006
AbstractUsing redox proteomics techniques to characterize the thiol status of proteins in human T lymphocytes, we identified cyclophilin A (CypA) as a specifically oxidized protein early after mitogen activation. CypA is an abundantly expressed cytosolic protein, target of the immunosuppressive drug cyclosporin A (CsA), for which a variety of functions
Ghezzi, Pietro   +14 more
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Redox Regulation of Chloroplast Transcription

Antioxidants & Redox Signaling, 2003
Chloroplasts are the important plant cell organelles where photosynthesis takes place. Throughout this process, reaction center proteins are degraded and subsequently replenished by redox-responsive gene expression. In addition to well defined posttranscriptional mechanisms at the RNA and protein level, the transcription of chloroplast DNA into RNA ...
openaire   +2 more sources

Redox Regulation in Oxigenic Photosynthesis

2002
Photosynthetic cells use the energy from absorbed light to synthesize partially or fully reduced organic compounds such as carbohydrates, fatty acids and amino acids from oxidized substrates. A series of elaborate redox reactions links the fundamental events of light absorption to the ultimate supply of reduced assimilates within the cell and also for ...
Link, G.   +3 more
openaire   +2 more sources

Redox regulation of Ran GTPase

Biochemical and Biophysical Research Communications, 2008
Ran, a small Ras-like GTP-binding nuclear protein, plays a key role in modulation of various cellular signaling events including the cell cycle. This study shows that a cellular redox agent (nitrogen dioxide) facilitates Ran guanine nucleotide dissociation, and identifies a unique Ran redox architecture involved in that process.
openaire   +2 more sources

Redox regulation of cell signalling

Nature, 1996
H M, Lander   +10 more
openaire   +2 more sources

Redox regulation of photosynthetic gene expression

Philosophical Transactions of the Royal Society B: Biological Sciences, 2012
Guillaume Queval, Christine H Foyer
exaly  

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