Results 91 to 100 of about 1,914,780 (311)

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Advanced System-Level Model Reduction Method for Multi-Converter DC Power Systems

open access: yesCSEE Journal of Power and Energy Systems
For dynamic stability analysis and instability mechanism understanding of multi-converter medium voltage DC power systems with droop-based double-loop control, an advanced system-level model reduction method is proposed.
Lin Zhu   +7 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Development of a Reduced Order Model of Solar Heat Gains Prediction

open access: yesEnergies, 2020
The aim of this study was to elaborate and validate a reduced order model able to forecast solar heat gains as a function of the architectural parameters that determine the solar heat gains.
Meril Tamm   +5 more
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

A Reduced-Order Model of Lithium–Sulfur Battery Discharge

open access: yesBatteries
This paper examines the problem of modeling lithium–sulfur (Li-S) battery discharge dynamics. The importance of this problem stems from the attractive specific energy levels achievable by Li-S batteries, which can be particularly appealing for ...
Noushin Haddad, Hosam K. Fathy
doaj   +1 more source

Reduced-Order Computational Model for Low-Frequency Dynamics of Automobiles

open access: yesAdvances in Mechanical Engineering, 2013
A reduced-order model is constructed to predict, for the low-frequency range, the dynamical responses in the stiff parts of an automobile constituted of stiff and flexible parts.
A. Arnoux   +3 more
doaj   +1 more source

Two-to-one resonant multi-modal dynamics of horizontal/inclined cables. Part II : internal resonance activation, reduced-order models and nonlinear normal modes

open access: yes, 2007
Resonant multi-modal dynamics due to planar 2:1 internal resonances in the nonlinear, finite-amplitude, free vibrations of horizontal/inclined cables are parametrically investigated based on the second-order multiple scales solution in Part I [1].
Rega, Giuseppe   +4 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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