Results 141 to 150 of about 854,050 (403)

Defined Electrosynthetic Microbial Consortia Reveal Electron Transfer Modes Governing Acetate Production

open access: yesAdvanced Science, EarlyView.
Spatially resolved Shewanella–acetogen interactions link DIET and MET pathways to acetate formation, offering a generalizable framework for designing structured, high‐efficiency microbial electrosynthesis systems. Abstract Precise manipulation of interspecies electron transfer (IET) is critical for advancing microbial electrosynthesis (MES) toward ...
Jing Zhang   +8 more
wiley   +1 more source

Thymidylate synthase and methylenetetrahydrofolate reductase gene polymorphisms: relationships with 5-fluorouracil sensitivity [PDF]

open access: hybrid, 2004
M-C Etienne   +7 more
openalex   +1 more source

DDDR-21. REGULATORY REDUCTASE SUBUNIT RRM2 AND DEHYDROGENASE IMPDH2 INTERACT IN GLIOBLASTOMA IN A TMZ-DEPENDENT MANNER [PDF]

open access: bronze, 2022
Graysen McManus   +14 more
openalex   +1 more source

Ir(III) Complexes Convert Cold to Hot Tumors via Ferroptosis/Necroptosis‐Driven Immunogenic Cell Death and Photosensitized CD47 Downregulation

open access: yesAdvanced Science, EarlyView.
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu   +8 more
wiley   +1 more source

Enhancement of seed phytosterol levels by expression of an N‐terminal truncated Hevea brasiliensis (rubber tree) 3‐hydroxy‐3‐methylglutaryl‐CoA reductase [PDF]

open access: hybrid, 2003
Mark Harker   +8 more
openalex   +1 more source

Regulation of nitrite reductase and lipid binding properties of cytoglobin by surface and distal histidine mutations

open access: green, 2022
Stefan J Kaliszuk   +8 more
openalex   +2 more sources

PFOS Disrupts Oocyte Maturation and Early Embryonic Development via Ovarian FOXK1 O‐GlcNAcylation in Mice

open access: yesAdvanced Science, EarlyView.
Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han   +16 more
wiley   +1 more source

Amodiaquine Enhances Anti‐Melanoma Efficacy of Attenuated Salmonella via Targeting Glutathione Reductase in Neutrophils

open access: yesAdvanced Science, EarlyView.
This study shows that Salmonella VNP20009 recruits pro‐tumor neutrophils that reduce its anticancer efficacy. Combining VNP with amodiaquine selectively eliminates these neutrophils by targeting glutathione reductase. A GR‐shRNA‐loaded VNP strain was further developed, demonstrating an innovative strategy integrating drug repurposing with synthetic ...
Wanfa Dong   +13 more
wiley   +1 more source

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