Results 41 to 50 of about 83,848 (260)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Dynamic reduction with applications to mathematical biology and other areas [PDF]

Journal of Biological Dynamics, 2007
In a difference or differential equation one is usually interested in finding solutions having certain properties, either intrinsic properties (e.g. bounded, periodic, almost periodic) or extrinsic properties (e.g. stable, asymptotically stable, globally asymptotically stable).
Robert J, Sacker, Hubertus F, Von Bremen
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

A study on the future cyclone characteristics and its associated storm surge along the Bangladesh coast

Quaternary Science Advances
This study has investigated the surge height along the Bangladesh coast due to the changes in future cyclone characteristics. Cyclone characteristics mainly translation speed, landfall angle, maximum sustained wind radius, genesis behavior etc., were ...
Md. Abdul Al Mohit, Masaru Yamashiro, Md. Towhiduzzaman, Atish Kumar Joardar   +3 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Pre-service mathematics teachers: Designing context-based tasks

Infinity
In the era of ever-evolving education, integrating real contexts into mathematics learning is essential to improve student engagement and understanding. The problem so far is that learning, including assessments used in mathematics learning, has not used
Imam Sujadi, Siti Suprihatiningsih, Muhammad Irfan, Lekë Pepkolaj   +3 more
doaj   +1 more source

Etnomatematika: Eksplorasi Budaya Sasak sebagai Sumber Belajar Matematika Sekolah Dasar

JRPM (Jurnal Review Pembelajaran Matematika), 2020
The purpose of this research is to describe the results of the exploration of ethnomathematics of Sasak culture that can be used as a source of learning mathematics. This type of research is exploratory qualitative research with an ethnographic approach.
Asri Fauzi, Aisa Nikmah Rahmatih, Muhammad Sobri, Radiusman Radiusman, Arif Widodo   +4 more
doaj   +1 more source

Mathematical Modelling of the Process of Tungsten Fluorides Reduction by Hydrogen [PDF]

MATEC Web of Conferences, 2016
The process of tungsten fluorides reduction by hydrogen is a component part of Fluoride technology of tungsten conversion. Nowadays the researchers are definitely interested in studying this process. It is connected with common use of metal tungsten products in different sectors of the economy, which is the result of unique qualities of this metal ...
Brendakov, Roman V., Shvab, Alexander V., Brendakov, Vladimir N.   +2 more
openaire   +3 more sources

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source