Results 91 to 100 of about 776,097 (338)

Protection costs, transaction costs,and economic theory [PDF]

open access: yes
Contractual reductionism takes market exchange as the ubiquitous form of economic organization throughout history. Transactions costs are accordingly regarded as the costs of running any economic system in general.
Vahabi, Mehrdad
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

open access: yesFEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom   +3 more
wiley   +1 more source

Desk study on homeopathy in organic livestock farming: Principles, obstacles and recommendations for practice and research [PDF]

open access: yes, 2003
Organic livestock farming has its own concept of health and welfare. The approach to health can be characterised by the key words human, preventive, self-regulating and holistic (Chapter 1).
Baars, Erik   +3 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

Łukasiewicz and Quine on Empirical and A Priori Sciences

open access: yesStudia Semiotyczne, 2020
DOI: http://doi.org/10.26333/sts.xxxiii2.07 Although Łukasiewicz and Quine do not share many common views, they agreed on one important point in the 1950s: they both denied the distinction between empirical and a priori sciences.
Zuzana Rybaříková
doaj  

Física e biologia: possíveis limites de demarcação conceitual Possible limits of conceptual demarcation

open access: yesTrans/Form/Ação, 2006
A partir do texto do físico alemão E.Schroedinger, O que é vida? (1943), analisam-se os possíveis limites de demarcação conceitual entre física e biologia. Há um limite possível entre física e biologia? Ou a biologia pode ser reduzida à física?
Arthur Araújo
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

RECIPIENT FACTOR IN POETIC TRANSLATION DIACHRONY

open access: yesRUDN Journal of Language Studies, Semiotics and Semantics, 2019
The paper's aim is to analyze transchronical interlingual and intercultural poetic communication. Special attention is paid to the recipient, his significance in diachronic translation is investigated.
Irina Nikolaevna Filippova
doaj   +1 more source

Reductionism and the Universal Calculus [PDF]

open access: yes, 2016
In the seminal essay, "On the unreasonable effectiveness of mathematics in the physical sciences," physicist Eugene Wigner poses a fundamental philosophical question concerning the relationship between a physical system and our capacity to model its ...
Sarma, Gopal P.
core   +1 more source

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