Results 101 to 110 of about 67,395 (285)

"In Defense of Pure Reason: A Rationalist Account of A Priori Justification" by Laurence BonJour [PDF]

open access: yes, 2003
Laurence BonJour divides approaches to a priori justification into three kinds. Quine’s radical empiricism denies the existence of any special category of a priori justification; moderate empiricism attempts to explain a priori ...
Crane, Tim
core  

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

open access: yesMolecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués   +3 more
wiley   +1 more source

Co je na životě tak zvláštního? Příklad redukcionismu René Descarta (What is so special about life? The example of René Descartes‘ reductionism )

open access: yesOstium, 2017
History of philosophy offers many examples capable of informing discussions related to questions, topics and problems, which are actual for both philosophy and particular scientific fields. Explanation of the nature of life is such a topic.
Vladimír Vodička
doaj  

Desk study on homeopathy in organic livestock farming: Principles, obstacles and recommendations for practice and research [PDF]

open access: yes, 2003
Organic livestock farming has its own concept of health and welfare. The approach to health can be characterised by the key words human, preventive, self-regulating and holistic (Chapter 1).
Baars, Erik   +3 more
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Hegel's Criticism of Newton's Physics: A Reconsideration" [PDF]

open access: yes, 2004
The persisting conception of Hegel's criticism of Newton's physics as an irrational or at least hopelessly exaggerated one partly has its roots mainly in Hegel's terminology and in his style.
Posch, Thomas
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

SOCIALITY PROBLEM IN THE CONTEXT OF CLASSICAL AND NONCLASSICAL INTERPRETATIONS

open access: yesВестник Кемеровского государственного университета, 2014
The paper shows that widespread approaches to studying society by means of allocating only one representative level within it are limited. As a possible the solution to this problem, the author suggests using the integrative approach which realizes the ...
E. O. Gavrilov
doaj  

Managing Complexity in Socio-Technical Systems by Mimicking Emergent Simplicities in Nature: A Brief Communication

open access: yesBiomimetics
In the context of socio-technical systems, traditional engineering approaches are inadequate, calling for a fundamental change in perspective. A different approach encourages viewing socio-technical systems as complex living entities rather than through ...
Andrea Falegnami   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

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