Results 91 to 100 of about 2,999 (176)
mBio, 2019 The genomes of Asgard Archaea, a novel archaeal proposed superphylum, share an enriched repertoire of eukaryotic signature genes and thus promise to provide insights into early eukaryote evolution.
Lokeshwaran Manoharan +5 more
doaj +1 more source
Radical-mediated ring contraction in the biosynthesis of 7-deazapurines [PDF]
, 2015 Pyrrolopyrimidine containing natural products are widely distributed in Nature. The biosynthesis of the 7-deazapurine moiety that is common to all pyrrolopyrimidines entails multiple steps, one of which is a complex radical-mediated ring contraction ...
Bandarian, Vahe, Drennan, Catherine L.
core +1 more source
Aspartimide Formation and Its Prevention in Fmoc Chemistry Solid Phase Peptide Synthesis
ChemBioChem, Volume 26, Issue 18, September 18, 2025.Aspartimide formation remains a persistent challenge in Fmoc solid phase peptide synthesis. This review surveys strategies to prevent aspartimide formation, covering protecting group design, backbone protection, and alternative deprotection approaches.
Marco J. W. Kong +2 more
wiley +1 more source
Investigations on a chloroform reductive dehalogenase
, 2017 Halogenated organic compounds (organohalides) are globally prevalent, recalcitrant toxic and carcinogenic environmental pollutants contaminating soil and groundwater. Organohalide respiring bacteria provide a potential solution to remediate contaminated sites, as they are capable of utilising organohalides as electron acceptors for the generation of ...
openaire +2 more sources
Cancer Medicine, Volume 14, Issue 18, September 2025.ABSTRACT Triple‐negative breast cancer (TNBC) is the most aggressive breast cancer subtype, lacking estrogen (ER), progesterone (PR), and human epidermal growth factor receptor (HER‐2) expression. It disproportionately affects women of African descent and has a poor clinical prognosis attributed to its acute heterogeneity, thereby causing elevated ...
Fleury Augustin Nsole Biteghe +11 more
wiley +1 more source
Insights Into the Biodegradation of Lindane (γ-Hexachlorocyclohexane) Using a Microbial System
Frontiers in Microbiology, 2020 Lindane (γ-hexachlorocyclohexane) is an organochlorine pesticide that has been widely used in agriculture over the last seven decades. The increasing residues of lindane in soil and water environments are toxic to humans and other organisms.
Wenping Zhang +9 more
doaj +1 more source
Frequent concomitant presence of Desulfitobacterium spp. and " Dehalococcoides ” spp. in chloroethene-dechlorinating microbial communities [PDF]
, 2018 The presence of chloroethene dechlorination activity as well as several bacterial genera containing mainly organohalide-respiring members was investigated in 34 environmental samples from 18 different sites.
Holliger, Christof +2 more
core
Identification of stable endogenous reference genes for real-time PCR in the human fetal gonad using an external standard technique [PDF]
, 2011 Peer ...
Ana Monteiro +13 more
core +1 more source
Computation of Protein Thermostability and Epistasis
WIREs Computational Molecular Science, Volume 15, Issue 5, September/October 2025.Conceptual illustration of computational prediction of protein thermostability and mutational epistasis. A neural network algorithm models changes in heat‐induced (un)folding by correlating sequence mutations with variations in free energy. The nonadditive nature of epistatic mutations is metaphorically represented by Orwell's infamous quote from ...
Francesca Peccati +3 more
wiley +1 more source
Advanced Science, Volume 12, Issue 32, August 28, 2025.DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan +4 more
wiley +1 more source