Results 91 to 100 of about 83,987 (180)

Evidence for a radical mechanism of the dechlorination of chlorinated propenes mediated by the tetrachloroethene reductive dehalogenase of Sulfurospirillum multivorans

, 2007
The reductive dehalogenation of chlorinated propenes was studied with the tetrachloroethene reductive dehalogenase purified from Sulfurospirillum multivorans to obtain indications for a radical mechanism of this reaction. When reduced methyl viologen (MV)
Neumann, A., Ploss, K., Habel, A., Boland, W., Diekert, G., Svatos, A., Schmitz, R., Wolf, J.   +7 more
core   +1 more source

HaloTag Fusion Enables Dynamic Analysis of Prion Protein Biosynthesis, Turnover, and Misfolding

ChemBioChem, Volume 27, Issue 11, 15 June 2026.
Prion protein (PrP) misfolding underlies fatal neurodegenerative diseases. We developed a HaloTag‐based PrP fusion enabling spatiotemporal labeling of distinct PrP populations in living cells. This system recapitulates native PrP biology, reveals early misfolding events in disease‐associated mutants, and allows mechanistic interrogation of PrP‐lowering
Antonio Masone, Eleonora Busani, Roberto Chiesa   +2 more
wiley   +1 more source

Desulfitobacterium elongatum sp. nov. NIT-TF6 Isolated from Trichloroethene-Dechlorinating Culture with Formate

Microorganisms
A strictly anaerobic bacterium denoted as strain NIT-TF6 of the genus Desulfitobacterium was isolated from a trichloroethene-dechlorinating culture with formate.
Udaratta Bhattacharjee, Ryuya Tomita, Li Xie, Naoko Yoshida   +3 more
doaj   +1 more source

Biochemical and genetic studies on reductive dehalogenases of Dehalococcoides sp. strain CBDB1

, 2005
Die vorliegende Arbeit beschreibt Eigenschaften der reduktiven Chlorbenzol-Dehalogenase aus Dehalococcoides sp. Stamm CBDB1, einem strikt anaeroben Bakterium, das Chlorbenzole als terminale Elektronenakzeptoren zur Energiegewinnung nutzt.
Hölscher, Tina
core   +1 more source

Desulfoluna spongiiphila strain AA1 and other marine sponge associated reductive debrominating bacteria

, 2021
Anaerobic microorganisms associated with marine sponges can reductively dehalogenate organohalide compounds. Desulfoluna spongiiphila strain AA1 isolated from the marine sponge Aplysina aerophoba is an anaerobic bacterium capable of growth by ...

core   +1 more source

Whole metagenome sequencing and 16S rRNA gene amplicon analyses reveal the complex microbiome responsible for the success of enhanced in-situ reductive dechlorination (ERD) of a tetrachloroethene-contaminated Superfund site.

PLoS ONE
The North Railroad Avenue Plume (NRAP) Superfund site in New Mexico, USA exemplifies successful chlorinated solvent bioremediation. NRAP was the result of leakage from a dry-cleaning that operated for 37 years.
Rebecca A Reiss, Peter A Guerra, Oleg Makhnin, Matthew Kellom   +3 more
doaj   +1 more source

Chlorine Isotope Effects from Isotope Ratio Mass Spectrometry Suggest Intramolecular C-Cl Bond Competition in Trichloroethene (TCE) Reductive Dehalogenation

Molecules, 2014
Chlorinated ethenes are prevalent groundwater contaminants. To better constrain (bio)chemical reaction mechanisms of reductive dechlorination, the position-specificity of reductive trichloroethene (TCE) dehalogenation was investigated.
Stefan Cretnik, Anat Bernstein, Orfan Shouakar-Stash, Frank Löffler, Martin Elsner   +4 more
doaj   +1 more source

Identification of a multi-protein reductive dehalogenase complex in Dehalococcoides mccartyi strain CBDB1 suggests a protein-dependent respiratory electron transport chain obviating quinone involvement

, 2016
Dehalococcoides mccartyi strain CBDB1 is an obligate organohalide-respiring bacterium using only hydrogen as electron donor and halogenated organics as electron acceptor.
Christian L. Schiffmann, Schiffmann, Christian L., Adarelys Andrades, Stefanie Hartwig, Darja Deobald, Andrades, Adarelys, R. Gary Sawers, Kublik, Anja, Hartwig, Stefanie, von Bergen, Martin, Lorenz Adrian, Anja Kublik, Deobald, Darja, Adrian, Lorenz, Sawers, R. Gary, Martin von Bergen   +15 more
core   +1 more source

Microbiome dynamics of a polychlorobiphenyl (PCB) historically contaminated marine sediment under conditions promoting reductive dechlorination

Frontiers in Microbiology, 2016
The toxicity of polychlorinated biphenyls (PCB) can be efficiently reduced in contaminated marine sediments through the reductive dechlorination process lead by anaerobic organohalide bacteria.
Bruna Matturro, Carla Ubaldi, Simona Rossetti   +2 more
doaj   +1 more source

[4Fe–4S]-Mediated Proton-Coupled Electron Transfer Enables the Efficient Degradation of Chloroalkenes by Reductive Dehalogenases

, 2023
Reductive dehalogenases (RDases) are key enzymes involved in the degradation of organohalide compounds. Despite extensive experimental and computational studies, the catalytic mechanism of RDases remains unclear. We show here that the proximal [4Fe–4S]1+
Wang, B., Shaik, S., Li, Z., Zhang, X., Wang, Z.   +4 more
core   +1 more source