Results 111 to 120 of about 5,571,829 (332)

Reference genome and demographic history of the most endangered marine mammal, the vaquita

open access: yesbioRxiv, 2020
The vaquita is the most critically endangered marine mammal, with fewer than 19 remaining in the wild. First described in 1958, the vaquita has been in rapid decline resulting from inadvertent deaths due to the increasing use of large-mesh gillnets for ...
P. Morin   +33 more
semanticscholar   +1 more source

De Novo Assembly of Nucleotide Sequences in a Compressed Feature Space [PDF]

open access: yes, 2017
Sequencing technologies allow for an in-depth analysis of biological species but the size of the generated datasets introduce a number of analytical challenges.
Robertson, David L., Tapinos, Avraam
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Development of SSR molecular markers based on the published genome in seashore paspalum

open access: yesGrass Research
Seashore paspalum (Paspalum vaginatum Swartz) is a widely utilized turfgrass in subtropical and tropical regions. To assist germplasm evaluation and breeding new varieties, a study was carried out to identify Simple Sequence Repeats (SSR) sites in the ...
Qian Chen   +3 more
doaj   +1 more source

One is not enough: on the effects of reference genome for the mapping and subsequent analyses of short-reads

open access: yesbioRxiv, 2020
Mapping of high-throughput sequencing (HTS) reads to a single arbitrary reference genome is a frequently used approach in microbial genomics. However, the choice of a reference may represent a source of errors that may affect subsequent analyses such as ...
Carlos Valiente-Mullor   +7 more
semanticscholar   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Improving Imputation Quality in BEAGLE for Crop and Livestock Data

open access: yesG3: Genes, Genomes, Genetics, 2020
Imputation is one of the key steps in the preprocessing and quality control protocol of any genetic study. Most imputation algorithms were originally developed for the use in human genetics and thus are optimized for a high level of genetic diversity ...
Torsten Pook   +6 more
doaj   +1 more source

Comparative Analysis of Genotyping by Sequencing and Whole-Genome Sequencing Methods in Diversity Studies of Olea europaea L.

open access: yesPlants, 2021
Olive, Olea europaea L., is a tree of great economic and cultural importance in the Mediterranean basin. Thousands of cultivars have been described, of which around 1200 are conserved in the different olive germplasm banks.
James Friel   +4 more
doaj   +1 more source

Paleoploidization events in the Musa (banana) lineage [PDF]

open access: yes, 2013
Bananas (Musa spp.) are giant perennial monocotyledonous herbs of the order Zingiberales, a sister group to the well-studied Poales. Cultivars are mainly triploid, from inter(sub)specific origin and clonally propagated.
Aury, Jean-Marc   +5 more
core  

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