Results 151 to 160 of about 5,571,829 (332)

Genome structure and content of the rice root‐knot nematode (Meloidogyne graminicola)

Ecology and Evolution, 2020
Discovered in the 1960s, Meloidogyne graminicola is a root‐knot nematode species considered as a major threat to rice production. Yet, its origin, genomic structure, and intraspecific diversity are poorly understood.
Ngan Thi Phan, Julie Orjuela, Etienne G. J. Danchin, Christophe Klopp, Laetitia Perfus‐Barbeoch, Djampa K. Kozlowski, Georgios D. Koutsovoulos, Céline Lopez‐Roques, Olivier Bouchez, Margot Zahm, Guillaume Besnard, Stéphane Bellafiore   +11 more
doaj   +1 more source

A complete assembly of the rice Nipponbare reference genome.

Molecular Plant, 2023
L. Shang, Wenchuang He, Tianyi Wang, Yingxue Yang, Qiang Xu, Xianjia Zhao, Longbo Yang, Hong Zhang, Xiaoxia Li, Yang Lv, Wu Chen, Shuo Cao, Xianmeng Wang, Bin Zhang, Xiangpei Liu, Xiaoman Yu, Huiying He, Hua Wei, Yue Leng, Chuanlin Shi, Mingliang Guo, Zhipeng Zhang, Bintao Zhang, Qiaoling Yuan, Hongge Qian, Xinglan Cao, Yan Cui, Qianqian Zhang, Xiaofan Dai, Congcong Liu, Longbiao Guo, Yongfeng Zhou, Xiaoming Zheng, Jue Ruan, Zhukuan Cheng, W. Pan, Qian Qian   +36 more
semanticscholar   +1 more source

Is it time to change the reference genome?

Genome Biology, 2019
The use of the human reference genome has shaped methods and data across modern genomics. This has offered many benefits while creating a few constraints.
Sara Ballouz, A. Dobin, J. Gillis
semanticscholar   +1 more source

The ATCC genome portal: 3,938 authenticated microbial reference genomes

Microbiology Resource Announcements
The ATCC Genome Portal (AGP, https://genomes.atcc.org/) is a database of authenticated genomes for bacteria, fungi, protists, and viruses held in ATCC's biorepository. It now includes 3,938 assemblies (253% increase) produced under ISO 9000 by ATCC. Here, we present new features and content added to the AGP for the research community.
Scott V. Nguyen, Nikhita P. Puthuveetil, Joseph R. Petrone, Jade L. Kirkland, Kaitlyn Gaffney, Corina L. Tabron, Noah Wax, James Duncan, Stephen King, Robert Marlow, Amy L. Reese, David A. Yarmosh, Hannah H. McConnell, Ana S. Fernandes, John Bagnoli, Briana Benton, Jonathan L. Jacobs   +16 more
openaire   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

Molecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian, Sriraam Sivachandran, Melissa Galati, Brandon Ramchatesingh, Hibo Rijal, Johnny Hanna, Elena Netchiporouk, May Chergui, Margaret Redpath, Samy Abou Setah, Ivan V. Litvinov   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

Molecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath, Irene A. George, Srikanth S. Manda, Prasanth Ariyannur, Ekta R. Dhawale, Raja Sekhar Kommu, Rajan Datar, Darshana Patil, Vinita Trivedi, Manisha Singh, Kumar Prabhash, Sewanti Limaye, Richa Chauhan, Prashant Kumar   +13 more
wiley   +1 more source

High-quality chromosome-scale assembly of the walnut (Juglans regia L.) reference genome

bioRxiv, 2019
The release of the first reference genome of walnut (Juglans regia L.) enabled many achievements in the characterization of walnut genetic and functional variation.
A. Marrano, M. Britton, Paulo A. Zaini, A. Zimin, R. Workman, D. Puiu, L. Bianco, E. D. Di Pierro, B. Allen, S. Chakraborty, M. Troggio, C. Leslie, W. Timp, A. Dandekar, S. Salzberg, D. Neale   +15 more
semanticscholar   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

A Genomic‐Based Workflow for eDNA Assay Development for a Critically Endangered Turtle, Myuchelys georgesi

Ecology and Evolution
Environmental DNA (eDNA) analysis has become a popular conservation tool for detecting rare and elusive species. eDNA assays typically target mitochondrial DNA (mtDNA) due to its high copy number per cell and its ability to persist in the environment ...
Holly V. Nelson, Arthur Georges, Katherine A. Farquharson, Elspeth A. McLennan, Jane L. DeGabriel, Katherine Belov, Carolyn J. Hogg   +6 more
doaj   +1 more source