Results 11 to 20 of about 5,571,829 (332)
Reference Based Genome Compression [PDF]
2012 IEEE Information Theory Workshop, 2012 DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot ...
Chern, Bobbie +5 more
core +4 more sources
Modernizing reference genome assemblies. [PDF]
PLoS Biology, 2011 I have read the journal's policy and have the following conflicts: Paul Flicek is married to the deputy editor of PLoS Medicine, Melissa Norton. Evan Eichler is on the board of Pacific Biosciences. Support for this work came from the Intramural Research Program of the NIH, The National Library of Medicine, the European Molecular Biology ...
Deanna M Church +38 more
doaj +5 more sources
The era of reference genomes in conservation genomics [PDF]
Trends in Ecology & Evolution, 2022 Trends in Ecology & Evolution, 37 (3)
Formenti, Giulio +157 more
+48 more sources
Reference flow: reducing reference bias using multiple population genomes [PDF]
Genome Biology, 2021 Abstract Most sequencing data analyses start by aligning sequencing reads to a linear reference genome, but failure to account for genetic variation leads to reference bias and confounding of results downstream. Other approaches replace the linear reference with structures like graphs that can include genetic variation, incurring ...
Nae-Chyun Chen +4 more
openaire +3 more sources
Ethnically relevant consensus Korean reference genome towards personal reference genomes [PDF]
Nature Communications, 2016 AbstractHuman genomes are routinely compared against a universal reference. However, this strategy could miss population-specific or personal genomic variations, which may be detected more efficiently using an ethnically-relevant and/or a personal reference.
Cho, Yun Sung +15 more
openaire +6 more sources
Improved annotation of 3' untranslated regions and complex loci by combination of strand-specific direct RNA sequencing, RNA-seq and ESTs [PDF]
, 2013 The reference annotations made for a genome sequence provide the framework for all subsequent analyses of the genome. Correct annotation is particularly important when interpreting the results of RNA-seq experiments where short sequence reads are mapped ...
A Derti +52 more
core +17 more sources
BMC Genomics, 2021 Background Faced with the ongoing global pandemic of coronavirus disease, the ‘National Reference Centre for Whole Genome Sequencing of microbial pathogens: database and bioinformatic analysis’ (GENPAT) formally established at the ‘Istituto ...
Adriano Di Pasquale +5 more
doaj +1 more source
Genetic Basis of Dorper Sheep (Ovis aries) Revealed by Long-Read De Novo Genome Assembly
Frontiers in Genetics, 2022 Dorper sheep (Ovis aries) (DPS), developed in the 1930s by crossing Dorset Horn and Blackhead Persian sheep in South Africa, is a world-famous composite breed for mutton production. The genetic basis underlying this breed is yet to be elucidated.
Guoyan Qiao +23 more
doaj +1 more source
Origin Matters: Using a Local Reference Genome Improves Measures in Population Genomics
bioRxiv, 2023 Genome-level sequencing enables us to ask fundamental questions about the genetic basis of adaptation, population structure, and epigenetic mechanisms, but usually requires a suitable reference genome for mapping population-level re-sequencing data.
Doko-Miles J. Thorburn +10 more
semanticscholar +1 more source
BMC Genomics, 2023 Background Genomic data-based machine learning tools are promising for real-time surveillance activities performing source attribution of foodborne bacteria such as Listeria monocytogenes.
Pierluigi Castelli +6 more
doaj +1 more source