Results 41 to 50 of about 28,569 (299)
ABSTRACT Background PIK3CA‐related overgrowth spectrum (PROS) includes several rare overgrowth disorders resulting from somatic gain‐of‐function mutations in PIK3CA. Despite treatment advances, including the recent approval of alpelisib for PROS in the United States, literature detailing the patient experience with PROS is limited.
Vamsi Bollu +8 more
wiley +1 more source
ABSTRACT Background 131I‐metaiodobenzylguanidine (131I‐MIBG) radiotherapy is a key treatment for relapsed and refractory (R/R) neuroblastoma (NB). Patients with R/R disease treated in the modern era are increasingly exposed to anti‐GD2 immunotherapy, which exerts selective pressure and may modify both tumor cell state and microenvironment.
Benjamin J. Lerman +7 more
wiley +1 more source
Inference in two-piece location-scale models with Jeffreys priors [PDF]
This paper addresses the use of Jeffreys priors in the context of univariate threeparameter location-scale models, where skewness is introduced by differing scale parameters either side of the location.
Rubio, Francisco J., Steel, Mark F. J.
core
Comment on “Reference priors for high energy physics”
A Bayesian reference analysis of a typical scenario of high energy physics has recently been performed [Phys. Rev. D 82, 034002 (2010)]. The reference prior with partial information (and hence also the posterior) were found to depend on the sequence of subsets of the parameter space used for a normalization process.
Grientschnig, Dieter, Lira, Ignacio
openaire +3 more sources
ABSTRACT Background Osteosarcoma (OS) and Ewing sarcoma (EWS) are the most common primary bone cancers in children, but acute thrombosis is poorly characterized in this population. Our study evaluated the rates of venous thromboembolism (VTE) and associated risk factors in pediatric patients with bone sarcomas treated over a 10‐year period encompassing
Sarah Kappa +8 more
wiley +1 more source
ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
wiley +1 more source
Reference priors in non-normal location problems [PDF]
Bayesian Statistics;Statistical ...
Fernández, C., Steel, M.F.J.
openaire +3 more sources
Population Pharmacokinetic Model of Adalimumab Based on Prior Information Using Real World Data
Adalimumab is a fully human monoclonal antibody used for the treatment of inflammatory bowel disease (IBD). Due to its considerably variable pharmacokinetics and the risk of developing antibodies against adalimumab, it is highly recommended to use a ...
Silvia Marquez-Megias +3 more
doaj +1 more source
PRIOR: Perceptive Learning for Humanoid Locomotion with Reference Gait Priors
Training perceptive humanoid locomotion policies that traverse complex terrains with natural gaits remains an open challenge, typically demanding multi-stage training pipelines, adversarial objectives, or extensive real-world calibration. We present PRIOR, an efficient and reproducible framework built on Isaac Lab that achieves robust terrain traversal
Chenxi Han +4 more
openaire +2 more sources
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
wiley +1 more source

