Results 121 to 130 of about 66,644 (298)
Corona XXXII: Keine Rechnung ohne die Gesellschaft
, 2022 Dirk Baecker Im dritten Jahr der Pandemie ist offenkundig, dass ein Frequenzmodell der Gesellschaft nicht genügt, die Reaktion der Gesellschaft auf die Pandemie zu beschreiben.
kure
core
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
, 2008 No es bueno, a estas alturas del tiempo y de la vida nacional, de la historia, seguir hablando de Áreas Revertidas… Asó perdemos conocimiento, y nos perdemos en la búsqueda ( y encuentro) de la verdad. Es que lo que revertió a Panamá fueron una portentosa obra de ingeniería y dos grandes ciudades, situadas al norte y al sur de la capital de la ...
openaire +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Gender-Reflexion im Vorbereitungsdienst
, 2017 König L, Firsching A. Gender-Reflexion im Vorbereitungsdienst. Presented at the Studienseminar für das Lehramt an Gymnasien und Gesamtschulen, Vortrag und zweiteiliger Workshop, 29.11.2017 ...
Firsching, A., König, Lotta
core
Lehrkompetenz und wissenschaftsbezogene Reflexion
, 2011 Dieser Aufsatz verfolgt die Frage, inwiefern Lehrkompetenz von wissenschaftsbezogener Reflexion profitieren kann. Dazu wird zunächst das Relationengefüge skizziert, in dem sich Hochschullehre bewegt.
Rüdiger Rhein
core +1 more source