Results 91 to 100 of about 1,855,208 (237)

Chronic cough diagnosis, treatment, and referral practices among family physicians in the United States: a survey study

BMC Primary Care
Background Cough is one of the most common presenting problems for patients in primary care and is largely managed in primary care clinical settings. Family physicians’ familiarity with chronic cough guidelines and the extent to which these guidelines ...
Joel B. Shields, Elisabeth Callen, Natalia Y. Loskutova, Jonathan Schelfhout, Christina M. Hester   +4 more
doaj   +1 more source

Glofitamab in combination with immunochemotherapy in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma: Phase 1b dose‐escalation study

British Journal of Haematology, EarlyView.
Summary Glofitamab was investigated with obinutuzumab/rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone (G/R‐CHOP) in patients with relapsed/refractory B‐cell non‐Hodgkin lymphoma (B‐NHL) who had ≥1 prior obinutuzumab/rituximab‐containing therapy (NCT03467373). The primary end‐point was to determine the optimal biological dose of
William Townsend, Nilanjan Ghosh, Martin Hutchings, Michael Dickinson, Monica Tani, Armando Santoro, Michael Crump, Amitkumar Mehta, Reinhard Marks, Martin Weisser, Martin Barrett, Chun Wu, Derrick Kaufman, Katharina Lechner, Pauline Baumlin, Pontus Lundberg, Max S. Topp   +16 more
wiley   +1 more source

Minimal residual disease–guided ibrutinib and venetoclax in patients with chronic lymphocytic leukaemia and complex karyotype

British Journal of Haematology, EarlyView.
Minimal residual disease (MRD)–guided ibrutinib and venetoclax (IVen) achieved durable remissions and high undetectable MRD (uMRD) rates in patients with high‐risk chronic lymphocytic leukaemia (CLL). Compared with historical ibrutinib monotherapy, IVen was associated with improved progression‐free and overall survival despite presence of complex ...
Maria Kislova, Elena Dmitrieva, Elena Naumova, Margarita Pochtar, Svetlana Lugovskaya, Yury Kobzev, Alla Loban, Maria Gladysheva, Tatiana Obukhova, Bella Biderman, Andrey Sudarikov, Egor Volchkov, Maria Ivanova, Vadim Ptushkin, Andrea Visentin, Eugene Nikitin   +15 more
wiley   +1 more source

Systematic literature review of treatments used for refractory or unexplained chronic cough in adults

Annals of Thoracic Medicine
BACKGROUND: Refractory or unexplained chronic cough (RCC or UCC) is difficult to manage and is usually treated by the off-label use of drugs approved for other indications.
Vishal Bali, Peter Kardos, Clive Page, Paola Rogliani, Luigino Calzetta, Ada Adriano, Aidan Byrne, Adekemi Adeyemi, Andrew Frederickson, Jonathan Schelfhout   +9 more
doaj   +1 more source

The development of the Cough Hypersensitivity Questionnaire for chronic cough

Introduction Chronic cough is considered a disorder of neuronal hypersensitivity in which patients frequently report abnormal laryngeal and chest sensations, and excessive triggers.
Peter S.P. Cho, Harini Kesavan, Richard J Siegert, Hirons, B, Kim, JY, Siegert, RJ, Turner, R, Rhatigan, K, Surinder S. Birring, Rhatigan, Katherine, Peter SP Cho, Kesavan, H, Hirons, Barnaby, Birring, SS, Richard Turner, Surinder S Birring, Krägeloh, Chris, Kesavan, Harini, Won, Ha-Kyeong, Won, HK, Krägeloh, C, Mackay, E, Turner, Richard, Barnaby Hirons, Ha-Kyeong Won, Katherine Rhatigan, Birring, Surinder S, Richard J. Siegert, Cho, PSP, Mackay, Ewan, Song, WJ, Chris Krägeloh, Woo-Jung Song, Kim, Ju-Young, Cho, Peter SP, Ju-Young Kim, Ewan Mackay, Song, Woo-Jung   +37 more
core   +1 more source

SAKK 35/14 randomized trial of rituximab with or without ibrutinib for patients with untreated follicular lymphoma

British Journal of Haematology, EarlyView.
Summary The randomized phase II SAKK 35/14 trial, conducted by the Swiss Group for Clinical Cancer Research (SAKK) and the Nordic Lymphoma Group (NLG), compared efficacy and safety of rituximab (375 mg/m2 intravenously for 4 weeks followed by maintenance every 2 months for 24 months) plus placebo (arm A) versus the same schedule of rituximab plus ...
Maria Cristina Pirosa, Marianne Brodtkorb, Sämi Schär, Björn E. Wahlin, Micaela Hernberg, Michael Pedersen, Anastasios Stathis, Thilo Zander, Urban Novak, Thorsten Zenz, Natalie Fischer, Fatime Krasniqi, Felicitas Hitz, Ann‐Sofie Johansson, David Löfgren, Peter Albert Meyer, Anne Turid Bjørnevik, Giulio Sartori, Stefanie Hayoz, Andrea Fuhrer, Luzia Steiner, Francesco Bertoni, Luca Ceriani, Stefan Dirnhofer, Emanuele Zucca, Bjørn Østenstad   +25 more
wiley   +1 more source

Burden of refractory and unexplained chronic cough on patients’ lives: a cohort study

, 2023
Refractory and unexplained chronic cough significantly impair patients’ quality of life, impacting their physical and psychological health, and everyday life.
Nieto, María Luisa, Cea Calvo, Luis, Quirce, Santiago, González Barcala, Francisco Javier, Rivas Pardinas, Cristina, Sola, Javier, Crespo Lessmann, Astrid, Martínez-Moragón, Eva, Sánchez Jareño, Marta, Domingo, Christian, Puente Maestu, Luis, Dávila González, Ignacio Jesús   +11 more
core   +1 more source

Peripheral targets for neuropathic pain

British Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour, Cosmin I. Ciotu, Felix J. Resch, Michael J. M. Fischer   +3 more
wiley   +1 more source

Profile of cough triggers and their relationship with capsaicin cough sensitivity in chronic cough

Therapeutic Advances in Respiratory Disease
Background: Cough hypersensitivity is an important part of the neurophysiology of cough, which presents with increased cough response to a lower level of stimuli or triggers.
Tingting Xu, Zhiyin Chen, Chen Zhan, Wenzhi Zhan, Fang Yi, Kefang Lai   +5 more
doaj   +1 more source

Diagnosed and undiagnosed cough-related stress urinary incontinence in women with refractory or unexplained chronic cough : Its impact on general health status and quality of life [PDF]

Background: Stress urinary incontinence (SUI) is common in women with chronic cough but may be overlooked. Objective: To determine the frequency of underdiagnosis of cough-related SUI and its impact on women's general health status and quality of life ...
Arismendi, Ebymar, González-Barcala, Francisco Javier, Puente-Maestu, Luis, González-Barcala, Francisco J., Sánchez-Jareño, Marta, Dávila, Ignacio, Rivas-Pardinas, Cristina, Cea-Calvo, Luis, Quirce, Santiago, Crespo-Lessmann, Astrid, Crespo Lessmann, Astrid, Universitat Autònoma de Barcelona, Domingo, Christian   +12 more
core   +1 more source