Results 91 to 100 of about 1,973,166 (180)

A pilot study for Basidiomycete-associated chronic cough: A potential contributor to refractory and unexplained or refractory chronic cough

Abstract Recent evidence suggests a potential association between chronic cough and environmental fungi, particularly basidiomycetes, giving rise to the concept of fungus-associated chronic cough (FACC). However, the role of basidiomycetes in chronic cough remains poorly understood.
Jun Iriki, Takahiro Takazono, Yasushi Obase, Yuka Nagae, Susumu Fukahori, Shinnosuke Takemoto, Noriho Sakamoto, Chizu Fukushima, Tomoya Nishino, Hiroshi Mukae   +9 more
openaire   +1 more source

The Genetic Architecture of Chronic Cough: From Sensory Hypersensitivity to Treatable Trait

Pulmonary Therapy
Chronic cough is a prevalent global clinical disorder with substantial quality-of-life impairment, and refractory cases remain a major unmet medical need.
Ran Dong, Mengru Zhang, Alyn H. Morice
doaj   +1 more source

Refractory Chronic Cough at the Crossroads

Archivos de Bronconeumología (English Edition), 2020
openaire   +2 more sources

Efficacy and safety of P2X3 receptor antagonists in refractory or unexplained chronic cough: an updated systematic review and meta-analysis

Frontiers in Pharmacology
BackgroundRefractory chronic cough and unexplained chronic cough are increasingly understood as clinical expressions of cough hypersensitivity. P2X3 receptor antagonists have been developed to reduce ATP-mediated airway sensory nerve activation, but ...
Yu-Tong An, Yu-Tong An, Shu-Ze Tang, Shu-Ze Tang, Yi Luo, Le Huang, Xiu-Juan Deng   +6 more
doaj   +1 more source

Patient satisfaction with the management of refractory and unexplained chronic cough in Canada: Results from a national survey.

PLoS ONE
BackgroundChronic cough (persisting for ≥8 weeks) is a common disorder affecting approximately 5 to 10% of adults worldwide that is sometimes refractory to treatment (refractory chronic cough [RCC]) or has no identifiable cause (unexplained chronic cough
Sana Khan, Danica Brister, Ted Abraham, Samuel Laventure, Sevag Sahakian, Berta Juliá, Imran Satia   +6 more
doaj   +1 more source

The Therapeutic Landscape in Chronic Cough

In recent years, there has been a substantial increase in the development of antitussive therapies and the first new therapy, gefapixant has been licenced in Europe.
Smith, Jaclyn A; id_orcid
core   +1 more source

Chronic cough: new concepts and therapeutic possibilities [PDF]

, 2016
Cough is the most common symptom of the upper and lower airway diseases. In its nature, cough is a defence re-flex mechanism of the respiratory tract that is used to clear the upper and lower airways. Chronic cough, defined as cough lasting for more than
Arcimowicz, Magdalenia, Niemczyk, Kazimierz   +1 more
core  

Characterization of Codeine Treatment Responders Among Patients with Refractory or Unexplained Chronic Cough: A Prospective Real-World Cohort Study

Purpose: Codeine is a narcotic antitussive often considered for managing patients with refractory or unexplained chronic cough. This study aimed to evaluate the proportion and characteristics of patients who responded to codeine treatment in real-world ...
Ji-Ho Lee, Kian Fan Chung, Seung-Eun Lee, Ji-Hyang Lee, So-Young Park, Eun-Jung Jo, Korean Chronic Cough Registry Study Group, Ji-Yoon Oh, Sang-Heon Cho, Sae-Hoon Kim, Youngsang Yoo, Ji-Su Shim, Jin An, Sung-Yoon Kang, Sang-Heon Kim, Byung-Jae Lee, Yoon-Seok Chang, Sang-Hoon Kim, Ha-Kyeong Won, Hwa Young Lee, Byung-Keun Kim, Mi-Yeong Kim, Min-Hye Kim, Woo-Jung Song, Young-Chan Kim, Noeul Kang, Han-Ki Park   +26 more
core   +1 more source

Bridging Clinical Phenotypes and Histopathological Endotypes in Refractory Chronic Cough. [PDF]

J Clin Med
Klimowicz K, Białek-Gosk K, Grabczak EM, Truba O, Żuchowska J, Cyran A, Paplińska-Goryca M, Nejman-Gryz P, Dąbrowska M.   +8 more
europepmc   +1 more source

New Insights Into Refractory Chronic Cough and Unexplained Chronic Cough: A 6-Year Ambispective Cohort Study. [PDF]

Allergy Asthma Immunol Res, 2023
Zhang M, Morice AH, Si F, Zhang L, Chen Q, Wang S, Zhu Y, Xu X, Yu L, Qiu Z.   +9 more
europepmc   +1 more source