Results 91 to 100 of about 17,784 (227)

Systematic literature review of treatments used for refractory or unexplained chronic cough in adults

Annals of Thoracic Medicine
BACKGROUND: Refractory or unexplained chronic cough (RCC or UCC) is difficult to manage and is usually treated by the off-label use of drugs approved for other indications.
Vishal Bali, Peter Kardos, Clive Page, Paola Rogliani, Luigino Calzetta, Ada Adriano, Aidan Byrne, Adekemi Adeyemi, Andrew Frederickson, Jonathan Schelfhout   +9 more
doaj   +1 more source

Profile of cough triggers and their relationship with capsaicin cough sensitivity in chronic cough

Therapeutic Advances in Respiratory Disease
Background: Cough hypersensitivity is an important part of the neurophysiology of cough, which presents with increased cough response to a lower level of stimuli or triggers.
Tingting Xu, Zhiyin Chen, Chen Zhan, Wenzhi Zhan, Fang Yi, Kefang Lai   +5 more
doaj   +1 more source

ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry

The International Classification of Diseases (ICD) system plays a key role in health data classification but currently lacks a specific code for refractory chronic cough (RCC). This study analyzed ICD-10 coding patterns among 331 RCC patients enrolled in
Kim, Yeonhee, Won, Ha Kyeong, on behalf of the Korean Chronic Cough Registry Investigators, Kim, Young Chan, Jo, Eun Jung, Shim, Ji Su, An, Jin, Chang, Yoon Seok, Shin, Min Hye, Jeong, Jiung, Kim, Min Hye, Lee, Hwa Young, Lee, Young Jae, Park, Kyung Eun, Lee, Seung Eun, Ahn, Kyung Min, Morice, Alyn H., Kang, Sung Yoon, Park, Han Ki, Lee, Byung Jae, Song, Woo Jung, Kim, So Ri   +21 more
core   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Evolving treatments for Sjögren disease: current approaches and emerging targets

Internal Medicine Journal, EarlyView.
Abstract Sjögren disease (SjD) is a prevalent systemic autoimmune condition characterised by exocrine gland dysfunction, systemic inflammation and heterogeneous organ involvement. Current management remains largely symptomatic, with no approved disease‐modifying therapies available and substantial unmet clinical need. However, advances in understanding
Mansi Bhurani, Adrian Y. S. Lee, Maureen Rischmueller, Alberta Hoi   +3 more
wiley   +1 more source

Essential medications in palliative care: an updated survey of Australian and New Zealand medical practitioners practising palliative care

Internal Medicine Journal, EarlyView.
Abstract Background Palliative care patients experience complex symptoms requiring varied pharmacological management. Medication choice depends on the underlying aetiology of symptoms, guideline recommendations, clinician preference and medication availability.
Jack Power, Tim Luckett, Richard McNeill, David Currow, Amanda Landers, Gregory B. Crawford, Slavica Kochovska, Philip Good, Jessica Boyley, Sungwon Chang, Lisa Mounsey   +10 more
wiley   +1 more source

Cerebellar ataxia, neuropathy and vestibular areflexia syndrome: a neurogenic cough prototype

ERJ Open Research
Chronic cough is a frequent disorder that is defined by cough of more than 8 weeks duration. Despite extensive investigation, some patients exhibit no aetiology and others do not respond to specific treatments directed against apparent causes of cough ...
Laurent Guilleminault, Stuart B. Mazzone, Pauline Chazelas, Simon Frachet, Anne-Sophie Lia, Laurent Magy   +5 more
doaj   +1 more source

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

OX40/OX40L modulation: A target for regulating T cells in cutaneous inflammatory disorders

Journal of the European Academy of Dermatology and Venereology, EarlyView.
OX40 and OX40L are a co‐stimulatory immune checkpoint pair. Modulation of this pair impacts multiple immune phenotypes and is an attractive target for immunotherapy in dermatological disorders. Trials are underway with the majority in atopic dermatitis and currently in phase 3 trials.
Aditya K. Gupta, Julia Steriopoulos, Vasiliki Economopoulos, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Unmet need for biomarkers in chronic cough: a review of current challenges and future directions

ERJ Open Research
The diagnosis, investigation and management of chronic cough remains a challenge for patients and physicians. Patients with chronic cough can spend many years being investigated for possible underlying conditions and have numerous therapies before a ...
Wafa Hassan, Feng Wei, Ruchong Chen, Imran Satia   +3 more
doaj   +1 more source