Results 111 to 120 of about 28,051 (225)
, 2007 A distressed mother attends the clinic with her three year old daughter, who developed an itchy rash. The rash is reddish and affects her face and wrists. The child is restless and has been scratching all night.
Formosa, Marie Claire
core
Acalabrutinib in Chronic Lymphocytic Leukemia: Pharmacology and Emerging Clinical Perspectives
European Journal of Haematology, Volume 116, Issue 6, Page 759-770, June 2026.ABSTRACT Acalabrutinib, a second‐generation Bruton's tyrosine kinase inhibitor (BTKi), is characterized by enhanced specificity and selectivity for BTK with minimal off‐target effects, offering a significant evolution in the treatment of chronic lymphocytic leukemia (CLL). Its mechanism of action, a covalent binding to Cys481 within the BTK active site,
Gianluca Gaidano, Romano Danesi
wiley +1 more source
Cerebellar ataxia, neuropathy and vestibular areflexia syndrome: a neurogenic cough prototype
ERJ Open ResearchChronic cough is a frequent disorder that is defined by cough of more than 8 weeks duration. Despite extensive investigation, some patients exhibit no aetiology and others do not respond to specific treatments directed against apparent causes of cough ...
Laurent Guilleminault +5 more
doaj +1 more source
The Pathogenic Triad of Chronic Cough: Postnasal Drip Syndrome, Asthma, and Gastroesophageal Reflux Disease [PDF]
, 2007 Chronic cough, lasting for 3 weeks or more, is one of the most common symptoms for which adult patients seek medical attention. The pathogenic triad of chronic cough is Postnasal Drip Syndrome (PNDS), Asthma, and Gastroesophageal Reflux Diseases (GERD ...
Rajabto, W. (Wulyo) +2 more
core +1 more source
International Journal of Cancer, Volume 158, Issue 10, Page 2674-2683, 15 May 2026.What's new? Mitogen‐activated protein kinase (MAPK) inhibitors are promising treatments for pediatric Langerhans cell histiocytosis (LCH), a rare heterogeneous neoplasm that often affects multiple organ systems. Which MAPK inhibitors are most effective against LCH remains uncertain.
Xue Tang +5 more
wiley +1 more source
Selinexor and Venetoclax Combination in Patients With Relapsed or Refractory Acute Myeloid Leukemia
American Journal of Hematology, Volume 101, Issue 5, Page 1019-1024, May 2026.ABSTRACT Preclinical studies showed a synergistic antileukemia activity with combination of selective XPO1 inhibitor selinexor (SEL) and venetoclax (VEN), with potential to overcome VEN resistance by reducing the anti‐apoptotic protein MCL1. In an investigator‐sponsored, open‐label, phase Ib study (NCT03955783), adult patients with relapsed or ...
Somedeb Ball +11 more
wiley +1 more source
Unmet need for biomarkers in chronic cough: a review of current challenges and future directions
ERJ Open ResearchThe diagnosis, investigation and management of chronic cough remains a challenge for patients and physicians. Patients with chronic cough can spend many years being investigated for possible underlying conditions and have numerous therapies before a ...
Wafa Hassan +3 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 5, May 2026.ABSTRACT In children with complete unilateral main bronchial obstruction from foreign body aspiration, positive pressure ventilation may overdistend the contralateral ventilated lung, leading to barotrauma and tension pneumothorax. Sudden hypoxemia and hypotension should prompt rapid clinical assessment, including lung ultrasound, and immediate ...
Kun Yue, Xuewu Ji, Yingying Sun, Yin Xia
wiley +1 more source
Subglottic Stenosis After Radioactive Iodine Treatment for Graves' Disease: A Case Report
Head &Neck, Volume 48, Issue 5, Page E54-E57, May 2026.ABSTRACT Background Subglottic stenosis (SGS) is a narrowing of the airway below the glottis and may be congenital or acquired. While prolonged intubation is the most common cause of acquired SGS, other etiologies remain incompletely understood. Methods A 37‐year‐old woman presented with a four‐year history of mild progressive stridor, dysphonia, and ...
Claire Ettlin +3 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 5, May 2026.ABSTRACT Background and Aims Obsessive–compulsive disorder (OCD) is a chronic condition associated with marked functional impairment and high rates of treatment resistance. Converging evidence implicates glutamatergic dysregulation in OCD pathophysiology.
Ahmad Zolghadriha +2 more
wiley +1 more source