Results 111 to 120 of about 1,855,208 (237)

Guideline for Medication Management of Distressing Symptoms in Older Patients Receiving End‐of‐Life Palliative Care

Journal of Evidence-Based Medicine, EarlyView.
ABSTRACT Older patients receiving end‐of‐life palliative care often present with multiple geriatric syndromes, frailty, and comorbid symptom burden, resulting in a high risk of medication‐related harm. This guideline focuses on pharmacological management of distressing symptoms in older patients receiving end‐of‐life or hospice‐oriented palliative care,
Daiping Li, Yanwu Yang, Yan Zhang, Jirong Yue, Birong Dong, Meiling Ge, National Clinical Research Center for Geriatrics, West China Hospital of Sichuan University   +7 more
wiley   +1 more source

Unmet need for biomarkers in chronic cough: a review of current challenges and future directions

ERJ Open Research
The diagnosis, investigation and management of chronic cough remains a challenge for patients and physicians. Patients with chronic cough can spend many years being investigated for possible underlying conditions and have numerous therapies before a ...
Wafa Hassan, Feng Wei, Ruchong Chen, Imran Satia   +3 more
doaj   +1 more source

Association of Mean Nocturnal Baseline Impedance and AFS EGJ Grading With AET‐Defined Reflux Burden in Korean Patients

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aim Diagnosing gastroesophageal reflux disease (GERD) is challenging in borderline acid exposure time (AET). The Lyon Consensus 2.0 defines AET ≥ 6% as pathological reflux; however, East Asian standards often apply a 4% threshold, creating a diagnostic gray zone.
Ye‐Rin Chae, Ga Hee Kim, Ji Soo Moon, Jin Won Chang, Ji Hoon Yoon, Da Hyun Jung, Jun Chul Park, Sung Kwan Shin, Sang Kil Lee, Yong Chan Lee   +9 more
wiley   +1 more source

Unraveling the neuro-immune axis in cough hypersensitivity: from pathogenesis to synergistic management

Frontiers in Medicine
Cough Hypersensitivity Syndrome (CHS) stands as the definitive pathological phenotype of refractory chronic cough, characterized by a sensory nervous system that over-reacts to even trivial, low-threshold stimuli.
Dingyi Shi, Dingyi Shi, Jia He, Jia He, Yajing Huang, Yajing Huang, Lisha Liu, Yunna Li, Yunna Li, Qi Liu, Qi Liu, Shunlin Peng, Shunlin Peng   +12 more
doaj   +1 more source

Sinusitis and chronic cough in children

, 2012
Nevin W Wilson, Mary Beth Hogan, Charles Bruce Harper, Kathy Peele, Sonia Budhecha, Vincent Loffredo, Vanessa WongUniversity of Nevada School of Medicine, Department of Pediatrics, Section of Allergy, Immunology and Pulmonology, Reno, NV, USABackground ...
Budhecha S, Harper CB, Wong V, Loffredo V, Peele K, Wilson NW, Hogan MB   +6 more
core  

A Pilot Placebo‐Controlled Randomized Trial of Repeated High‐Dose Intravenous Magnesium Sulphate and High‐Dose Nebulized Budesonide for Severe Asthma in the Paediatric Emergency Department

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Determine if high‐dose intravenous magnesium with/without nebulized budesonide for children with acute severe asthma is safe and reduces time to medical readiness for discharge compared to standard intravenous magnesium. Methods Either 2 doses of intravenous magnesium or 1 dose and placebo, each with/without high‐dose nebulized ...
Khalid Alansari, Fatin Abou Moussa, Hadi Abu Rasheed, Bruce L. Davidson, Khalid Yousif Ibrahim, Mahmoud Alrifaai   +5 more
wiley   +1 more source

When Refractory Is Not the End: Redefining Chronic Cough Through Tertiary Center Evaluation

Mayo Clinic Proceedings: Innovations, Quality & Outcomes
Objective: To describe the clinical outcomes of refractory chronic cough (RCC) diagnosis and management at a tertiary care chronic cough clinic. Patients and Methods: This is a prospective study of all eligible patients referred to the Mayo Clinic ...
Sumera R. Ahmad, MBBS, Vivek N. Iyer, MBBS, Allison LeMahieu, MS, Vaibhav Ahluwalia, MBBS, Vibhor Ahluwalia, MBBS, Kinnera Jalagam, MBBS, Sue Ann Donlinger, LPN, Kaiser Lim, MD   +7 more
doaj   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Age‐Dependent Role of Cough Hypersensitivity in Transition to Refractory Chronic Cough

Clinical &Experimental Allergy, EarlyView.
Sung‐Yoon Kang, Ha‐Kyeong Won, Mi‐Yeong Kim, Ji‐Hyang Lee, Jin An, Ji‐Yoon Oh, Jiung Jeong, Young‐Chan Kim, So‐Young Park, Hwa Young Lee, Eun‐Jung Jo, Kyung‐Min Ahn, Min‐Hye Kim, So Ri Kim, Sae‐Hoon Kim, Sang‐Heon Kim, Yoon‐Seok Chang, Byung‐Jae Lee, Surinder S. Birring, Woo‐Jung Song, on behalf of the Korean Chronic Cough Registry investigators   +20 more
wiley   +1 more source

Sustained Remission of Pediatric Bowel‐Associated Dermatosis‐Arthritis Syndrome With Risankizumab

Pediatric Dermatology, EarlyView.
ABSTRACT Bowel‐associated dermatosis‐arthritis syndrome (BADAS) is a rare neutrophilic dermatosis characterized by recurrent fever, arthralgias, and skin eruptions, most commonly occurring in patients with inflammatory bowel disease. We report the case of a 17‐year‐old female with Crohn's disease who developed BADAS and achieved complete and durable ...
Kylie E. Peake, Harman Toor, Marie‐Christine Jean, Collin C. Barker, Joseph M. Lam   +4 more
wiley   +1 more source