Results 101 to 110 of about 1,855,208 (237)

Efficacy and safety of gefapixant, a P2X₃ receptor antagonist, in refractory chronic cough and unexplained chronic cough (COUGH-1 and COUGH-2): results from two double-blind, randomised, parallel-group, placebo-controlled, phase 3 trials

, 2022
Background: Gefapixant is an oral P2X3 receptor antagonist that has previously shown efficacy and safety in refractory chronic cough and unexplained chronic cough.

core   +1 more source

Nasal Obstruction Is Reduced 5–7 Years After Radiofrequency Turbinate Reduction: Results From a Retrospective Observational Cohort Study

Clinical Otolaryngology, EarlyView.
ABSTRACT Introduction Nasal obstruction, often caused by structural and inflammatory conditions, is prevalent and significantly impacts health‐related quality of life. Radiofrequency Turbinate Reduction (RFTR) is a widely employed treatment for inferior turbinate hypertrophy, yet evidence of its long‐term effectiveness remains limited. This study aimed
Veronica Ahlund, Pål Rosholm Comstedt, Maria Värendh, Pernilla Sahlstrand‐Johnson   +3 more
wiley   +1 more source

ICD-10 Diagnostic Coding Patterns and Clinical Correlates in Refractory Chronic Cough: Analysis from the Korean Chronic Cough Registry

The International Classification of Diseases (ICD) system plays a key role in health data classification but currently lacks a specific code for refractory chronic cough (RCC). This study analyzed ICD-10 coding patterns among 331 RCC patients enrolled in
Kim, Yeonhee, Won, Ha Kyeong, on behalf of the Korean Chronic Cough Registry Investigators, Kim, Young Chan, Jo, Eun Jung, Shim, Ji Su, An, Jin, Chang, Yoon Seok, Shin, Min Hye, Jeong, Jiung, Kim, Min Hye, Lee, Hwa Young, Lee, Young Jae, Park, Kyung Eun, Lee, Seung Eun, Ahn, Kyung Min, Morice, Alyn H., Kang, Sung Yoon, Park, Han Ki, Lee, Byung Jae, Song, Woo Jung, Kim, So Ri   +21 more
core   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

Diabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo, Bianca Aparecida Siqueira, Luiz Felipe Azevedo Marques, Lucas Silva Mello, Fernando Augusto Lima Marson   +4 more
wiley   +1 more source

Cerebellar ataxia, neuropathy and vestibular areflexia syndrome: a neurogenic cough prototype

ERJ Open Research
Chronic cough is a frequent disorder that is defined by cough of more than 8 weeks duration. Despite extensive investigation, some patients exhibit no aetiology and others do not respond to specific treatments directed against apparent causes of cough ...
Laurent Guilleminault, Stuart B. Mazzone, Pauline Chazelas, Simon Frachet, Anne-Sophie Lia, Laurent Magy   +5 more
doaj   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

European Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Clarifying Terminology in Chronic Cough: The Evolving Role of Cough Hypersensitivity Syndrome

The Clinical Respiratory Journal
Chronic cough is defined as a cough lasting no less than 8 weeks, and 10%–42% of patients with chronic cough retain their cough after comprehensive examination and treatment.
Zihang Wang, Yaxing Zhou, Yingchun Ren, Jiaying Yuan, Tongyangzi Zhang, Shengyuan Wang, Wanzhen Li, Li Yu, Xianghuai Xu   +8 more
doaj   +1 more source

Equine vegetative endocarditis and vertebral osteomyelitis due to refractory Erysipelothrix rhusiopathiae infection

Equine Veterinary Education, EarlyView.
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou, Z. Daobry, Â. J. F. Mendes, G. Weller, S. Radhakrishnan, M. S. I. Sajib, M. Fuentes, F. Zendri, T. Forde, W. Weir, J. Del‐Pozo, D. G. M. Sutton   +11 more
wiley   +1 more source

Effectiveness of the P2X3 Antagonist Gefapixant for Refractory Atopic Cough: A Retrospective Cohort Study

Journal of Asthma and Allergy
Yoshihisa Ishiura,1,2 Shosaku Nomura,1,2 Noriyuki Ohkura,3 Johsuke Hara,3 Masaki Fujimura,3 Tomoki Ito1,2 1First Department of Internal Medicine, Kansai Medical University, Osaka, Japan; 2Respiratory Medicine, Kansai Medical University Medical Center ...
Ishiura Y, Nomura S, Ohkura N, Hara J, Fujimura M, Ito T   +5 more
doaj  

3 year old with chronic wet cough : Intralobar Bronchopulmonary sequestration [PDF]

, 2016
Bronchopulmonary sequestration (BPS) is a rare congenital foregut anomaly of the lung, consisting of nonfunctioning primitive tissue that does not communicate with the healthy tracheobronchial tree.
Micallef, S.P., Sammut, Patrick, DeGiovanni, Joseph V., Grech, Victor E.   +3 more
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