Results 81 to 90 of about 17,784 (227)
Allergy, EarlyView.ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh +7 more
wiley +1 more source
Integrated Clinical Trial and Molecular Profiling Reveals Immune Drivers of Chronic Hand Eczema
Allergy, EarlyView.This study performed an unbiased molecular profiling of CHE patients across diverse etiologies to identify shared pathogenic drivers and evaluate the impact of IL‐4Rα blockade via dupilumab over 16 weeks. CHE shows a mixed immune signature involving type 1, 2, and 3 pathways with features of atopic dermatitis and psoriasis.
Perrine Gery +25 more
wiley +1 more source
Cough in idiopathic pulmonary fibrosis
European Respiratory Review, 2016 Many patients with idiopathic pulmonary fibrosis (IPF) complain of chronic refractory cough. Chronic cough is a distressing and disabling symptom with a major impact on quality of life.
Mirjam J.G. van Manen +6 more
doaj +1 more source
Clinical Features of Cellular Senescence Pathways in Severe Asthma
Allergy, EarlyView.In bronchial biopsies, SASP and p53 pathway enrichment scores are elevated in severe asthma versus non‐severe asthma and healthy controls. SASP enrichment is validated in the independent NOVA cohort. SASP enrichment is also elevated in nasal brushings of participants with nasal polyps, independently of asthma status.
Woo‐Jung Song +122 more
wiley +1 more source
Diagnosed and undiagnosed cough-related stress urinary incontinence in women with refractory or unexplained chronic cough : Its impact on general health status and quality of life [PDF]
Background: Stress urinary incontinence (SUI) is common in women with chronic cough but may be overlooked. Objective: To determine the frequency of underdiagnosis of cough-related SUI and its impact on women's general health status and quality of life ...
Arismendi, Ebymar +12 more
core +1 more source
BMC Primary CareBackground Cough is one of the most common presenting problems for patients in primary care and is largely managed in primary care clinical settings. Family physicians’ familiarity with chronic cough guidelines and the extent to which these guidelines ...
Joel B. Shields +4 more
doaj +1 more source
The development of the Cough Hypersensitivity Questionnaire for chronic cough
Introduction Chronic cough is considered a disorder of neuronal hypersensitivity in which patients frequently report abnormal laryngeal and chest sensations, and excessive triggers.
Peter S.P. Cho +37 more
core +1 more source
Tracheobronchopathia osteochondroplastica: A rare cause of chronic cough with haemoptysis
, 2008 4 S.A case of tracheobronchopathia osteochondroplastic (TPO) was diagnosed in a 69-year old male with prolonged cough. TPO is a rare condition of unknown cause and only sporadic cases have been reported.
Volker Wiechmann +7 more
core +1 more source
Effect of pregabalin for the treatment of chronic refractory cough
Medicine, 2019 Abstract Rationale: Chronic refractory cough (CRC) is a common clinical problem which is more likely associated with some physical problems. Although many patients have received satisfactory treatment, there were still many patients suffered from long-term cough symptoms after standardized treatment.
Li, Jun, Ye, Ling
openaire +2 more sources
Community Dentistry and Oral Epidemiology, EarlyView.ABSTRACT Objectives The objective of this scoping review was to map existing literature on oral health and related care in individuals with Motor Neurone Disease (MND). Specifically, the review aimed to identify barriers and facilitators to maintaining oral hygiene, summarise available clinical guidelines and patient‐facing resources, and examine how ...
Mariam A. Khokhar +3 more
wiley +1 more source