Results 81 to 90 of about 28,051 (225)

Aplastic Crisis as Primary Manifestation of Systemic Lupus Erythematosus [PDF]

, 2011
Aplastic crisis is an unusual feature of systemic lupus erythematosus (SLE). We report the case of a 54-year-old woman presenting with both (extravascular) Coombs-positive hemolytic anemia and laboratory findings of bone marrow hyporegeneration with ...
Alger M, Andreas Völkl, Bailey FA, Brooks, Chute JP, Espinoza JL, Feng X, Fuat S. Oduncu, Hinterberger-Fischer M, Hirano N, Hirano N, Mestanza-Peralta M, Michael Bäuerle, Pavithran K, Philipp Baumann, Ralf Schmidmaier, Singh NP, Tagoe C, Takamatsu H, Tan EM, Torok-Storb B, Wolach B, Young NS, Young NS   +23 more
core   +1 more source

Evidence‐based guideline for clinical practice in the diagnosis, treatment, management, and prevention of recurrent wheezing in infants and toddlers in China

Pediatric Investigation, EarlyView.
ABSTRACT Wheezing is a common respiratory symptom in infants and toddlers, and recurrent wheezing is a significant respiratory disorder affecting this age group. Given the multifactorial etiology of recurrent wheezing, clinical practice lacks standardized diagnostic and therapeutic protocols. Recent years have witnessed substantial progress in clinical
Committee of Pediatrics, China Medical Education Association, Cooperative Group of Asthma, the Subspecialty Group of Respiratory, the Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of the Chinese Non‐public Medical Institutions Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China News of Drug Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, China International Medical Foundation   +16 more
wiley   +1 more source

Traditional Chinese Medicine for lung cancer: Mechanisms, clinical evidence, and future perspectives

Precision Medical Sciences, EarlyView.
Graphical abstract represents the risk factors for lung cancer, TCM efficacy and clinical outcomes to future challenges. Abstract Lung cancer remains a leading cause of global cancer mortality. Despite advances in conventional treatments such as surgery, chemotherapy, targeted therapy, and immunotherapy, challenges including drug resistance, toxicity ...
Zhangdeng Chen, Liujun Bao
wiley   +1 more source

Exploring the Potential of a P2X3 Receptor Antagonist: Gefapixant in the Management of Persistent Cough Associated with Interstitial Lung Disease

Medicina
Background: Interstitial lung disease (ILD) is characterized by pulmonary inflammation and fibrosis associated with persistent and refractory cough that significantly hinders quality of life.
Tomoyuki Takahashi, Atsushi Saito, Takafumi Yorozuya, Hirotaka Nishikiori, Koji Kuronuma, Hirofumi Chiba   +5 more
doaj   +1 more source

Obesity and Its Impact on Endoscopic Sinus Surgery Outcomes in Patients With Chronic Rhinosinusitis With Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Purpose The rising prevalence of obesity introduces challenges in surgical contexts, including endoscopic sinus surgery (ESS) for chronic rhinosinusitis with nasal polyps (CRSwNP). However, the impact of obesity on ESS outcomes remains underexplored. This study aims to evaluate the association between obesity and surgical complexity, operative
Hen Chaushu, Narin Nard Carmel Neiderman, Yuval Presman, Alexandra Dorman, Roni Vass, Nidal Muhanna, Avraham Abergel   +6 more
wiley   +1 more source

Research Progress on Upper Airway Cough Syndrome

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Upper airway cough syndrome (UACS) has been identified as a significant contributor to chronic cough in various national guidelines. However, the complexity of its pathogenesis, the lack of clarity surrounding its diagnostic criteria, and its overlap with other etiologies of chronic cough present considerable challenges in both diagnosis and ...
Wan‐Ting Huang, Jia Chen
wiley   +1 more source

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

Allergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh, Lior Seluk, Philipp Bosch, Carolina Aguiar, Jens Thiel, Bernhard Hellmich, Michael E. Wechsler, Salman Siddiqui   +7 more
wiley   +1 more source

Real-world usage and response to gefapixant in refractory chronic cough

ERJ Open Research
Background The real-world efficacy of the P2X3 antagonist gefapixant, a new class of antitussive for refractory chronic cough, is not yet fully understood.
Hisako Matsumoto, Yoshihiro Kanemitsu, Motoki Ohe, Hiroshi Tanaka, Kunihiko Terada, Koichi Nishi, Ryo Atsuta, Johsuke Hara, Junpei Saito, Mitsuhide Ohmichi, Tamotsu Ishizuka, Teruaki Nishiuma, Hideki Inoue, Naoto Watanabe, Tatsuya Nagano, Tetsuya Ueda, Haruhiko Ogawa, Shigeru Endo, Takeshi Suzuki, Toshiyuki Kita, Katsuya Fujimori, Yoshihisa Ishiura, Masaki Fujimura, Akio Niimi   +23 more
doaj   +1 more source

Cough in idiopathic pulmonary fibrosis

European Respiratory Review, 2016
Many patients with idiopathic pulmonary fibrosis (IPF) complain of chronic refractory cough. Chronic cough is a distressing and disabling symptom with a major impact on quality of life.
Mirjam J.G. van Manen, Surinder S. Birring, Carlo Vancheri, Vincent Cottin, Elisabetta A. Renzoni, Anne-Marie Russell, Marlies S. Wijsenbeek   +6 more
doaj   +1 more source

TL1A/DR3 axis involvement in the inflammatory cytokine network during pulmonary sarcoidosis [PDF]

, 2015
BACKGROUND: TNF-like ligand 1A (TL1A), a recently recognized member of the TNF superfamily, and its death domain receptor 3 (DR3), firstly identified for their relevant role in T lymphocyte homeostasis, are now well-known mediators of several immune ...
A. Cabrelle, A. Teramo, C Agostini, C Agostini, C Agostini, C Agostini, C Agostini, C Agostini, C. Agostini, F Meylan, F. Calabrese, F. Calzetti, F. Cinetto, G Bamias, G Bamias, G Bamias, G Mautino, G. Semenzato, GW Jones, J Müller-Quernheim, KA Oswald-Richter, KL Wallace, KS Lee, L Li, L Nissinen, M Facco, M Facco, M. A. Cassatella, M. Facco, MA Cassatella, MA Judson, MT Henry, N Kamada, N Kamada, N. Tamassia, R Polverosi, RE Vandenbroucke, S. Carraro, SK Bedoya, TH Schreiber, TS Migone, V. Martini, VY Taraban, X Sun, Y Aiba, YJ Kang   +45 more
core   +1 more source