Results 71 to 80 of about 26,442 (182)

Effectiveness of the P2X3 Antagonist Gefapixant for Refractory Atopic Cough: A Retrospective Cohort Study

open access: yesJournal of Asthma and Allergy
Yoshihisa Ishiura,1,2 Shosaku Nomura,1,2 Noriyuki Ohkura,3 Johsuke Hara,3 Masaki Fujimura,3 Tomoki Ito1,2 1First Department of Internal Medicine, Kansai Medical University, Osaka, Japan; 2Respiratory Medicine, Kansai Medical University Medical Center ...
Ishiura Y   +5 more
doaj  

Female predominance in chronic cough: biological sex–related factors, mechanisms, and therapeutic targets—a narrative review

open access: yesFrontiers in Medicine
Chronic cough—defined in adults as cough lasting ≥8 weeks—shows higher prevalence in women. Accumulating evidence supports a cough hypersensitivity phenotype with peripheral and central drivers that may vary by biological sex.
Aibo Zheng   +6 more
doaj   +1 more source

A phase IIa study of the anti‐PD‐L1 antibody avelumab in relapsed/refractory PTCL: The AVAIL‐T trial

open access: yesBritish Journal of Haematology, EarlyView.
The AVAIL‐T study, the first evaluation of programmed death ligand 1 (PD‐L1) blockade in relapsed/refractory peripheral T‐cell lymphomas (PTCL), demonstrated limited single agent activity with durable responses seen in a minority. Circulating tumour DNA revealed distinct mutational dynamics and mass cytometry identified perturbed T‐cell subsets ...
Matthew J. Ahearne   +28 more
wiley   +1 more source

Peripheral targets for neuropathic pain

open access: yesBritish Journal of Pharmacology, EarlyView.
Neuropathic pain represents a significant clinical challenge, with still limited pharmacological approaches to symptomatic relief. This review focuses on molecular targets implicated in neuropathic pain, particularly those involved in peripheral mechanisms. Using the IUPHAR/BPS database of biological targets, their occurrence together with ‘neuropathic
Amirhossein Afsharipour   +3 more
wiley   +1 more source

Somatic symptom disorder comorbidity in chronic cough: prevalence, clinical features, and neuroimaging characteristics

open access: yesBMC Pulmonary Medicine
Background This study was aimed at exploring the prevalence of somatic symptom disorder (SSD) in patients with chronic cough and comparing SSD comorbid (SSD+) and non-comorbid (SSD−) groups, including sociodemographic, clinical, psychological, and ...
Tongyangzi Zhang   +10 more
doaj   +1 more source

Innovative Tools and Perspectives in Cough Management: Cancer and Cough [PDF]

open access: yesTuberculosis and Respiratory Diseases
Cough is a prevalent symptom in lung cancer that impairs quality of life. Postoperative cough after pulmonary resection (CAP) has an incidence of approximately 21.1%–55.8%.
Juwhan Choi, Sung Yong Lee
doaj   +1 more source

The burden of COVID‐19 in hospitalized people with diabetes mellitus in Brazil: Insights from four years of the pandemic

open access: yesDiabetic Medicine, EarlyView.
Abstract Aims Coronavirus disease 2019 (COVID‐19), caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), is more severe in people with diabetes mellitus due to immune dysfunction, exacerbated inflammation and increased risk of co‐morbidities and mortality.
Taís Mendes Camargo   +4 more
wiley   +1 more source

Cough in idiopathic pulmonary fibrosis

open access: yesEuropean Respiratory Review, 2016
Many patients with idiopathic pulmonary fibrosis (IPF) complain of chronic refractory cough. Chronic cough is a distressing and disabling symptom with a major impact on quality of life.
Mirjam J.G. van Manen   +6 more
doaj   +1 more source

Eosinophilia and Hypereosinophilia: A Practical Approach to Navigating a Broad Differential Diagnosis

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Eosinophilia, defined as an absolute eosinophil count (AEC) of ≥ 0.5 × 109/L, is a frequently encountered finding with a vast spectrum of potential underlying etiologies. Hypereosinophilia (HE) is defined as AEC > 1.5 × 109/L and may become life‐threatening when eosinophil‐induced organ damage occurs, defining the hypereosinophilic syndrome ...
Stijn Wigerinck, Peter Vandenberghe
wiley   +1 more source

Equine vegetative endocarditis and vertebral osteomyelitis due to refractory Erysipelothrix rhusiopathiae infection

open access: yesEquine Veterinary Education, EarlyView.
Summary Erysipelothrix rhusiopathiae was the causative agent of vegetative endocarditis and vertebral osteomyelitis in a 24‐year‐old Irish draught gelding that presented with prolonged history of intermittent pyrexia and tachycardia. Clinical investigations revealed persistently reduced neck mobility, tachydysrhythmia and episodic pyrexia up to 41°C ...
E. Kolovou   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy