Background Mexiletine is used as a preventive medication for refractory chronic migraine (rCM) and to prolong migraine improvement following intravenous lidocaine infusion. However, published evidence supporting its use in migraine remains limited.
Lucia Liao +5 more
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Clopidogrel can be an effective complementary prophylactic for drug-refractory migraine with patent foramen ovale. [PDF]
Guo Y, Shi Y, Zhu D, Liu R, Qi Y, Luo G.
europepmc +1 more source
Stroke-like migraine attacks after radiation therapy (SMART) syndrome is an infrequently reported complication arising years after radiation therapy that manifests as a reversible syndrome marked by migraine-like headaches, focal neurologic signs, and/or
Kyle N. Kaneko +4 more
doaj +1 more source
Updated Evaluation of IV Dihydroergotamine (DHE) for Refractory Migraine: Patient Selection and Special Considerations. [PDF]
Shafqat R +3 more
europepmc +1 more source
Lasmiditan for the treatment of acute migraine: a review and potential role in clinical practice
Jessica C Oswald, Nathaniel M Schuster UCSD Center for Pain Medicine, La Jolla, CA, USA Abstract: Now that the vascular hypothesis of migraine is no longer the prevailing theory of migraine pathogenesis, there is interest in developing acute migraine ...
Oswald JC, Schuster NM
doaj
Background: Despite the emergence of novel targeted therapies, refractory migraine remains a major clinical challenge. According to the 2020 European Headache Federation (EHF) Consensus, patients experiencing ≥8 debilitating headache days per month are classified as "resistant" if they have failed at least three classes of preventive treatments, and as
openaire +1 more source
Cannabidiol in the treatment of migraine: studies and future perspectives
Introduction: Migraine is one of the most disabling and prevalent conditions in the population. Is related to the release of pro-inflammatory mediators in the central nervous system, triggering painful episodes.
Taianara Sampaio Reis +7 more
doaj +2 more sources
Pharmacological mechanisms underlying neurovascular alterations related to resistant and refractory migraine: CGRP pathways and beyond. [PDF]
Scuteri D +11 more
europepmc +1 more source
Resolution of chronic refractory migraine and development of burning mouth syndrome after focused ultrasound thalamotomy: illustrative case. [PDF]
Shemesh SZ +4 more
europepmc +1 more source
Enhancing evidence for surgical treatment of refractory migraine suggestions on literature and study design. [PDF]
Lu Z, Wang M, Wang Y.
europepmc +1 more source

