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Defining Refractory Migraine and Refractory Chronic Migraine: Proposed Criteria From the Refractory Headache Special Interest Section of the American Headache Society [PDF]
Certain migraines are labeled as refractory, but the entity lacks a well‐accepted operational definition. This article summarizes the results of a survey sent to American Headache Society members to evaluate interest in a definition for RM and what were considered necessary criteria.
Richard B. Lipton +2 more
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Current Concepts in Refractory Migraine
Current Treatment Options in Neurology, 2012The Refractory or Intractable Migraine (RM) patient has long been a challenge to all healthcare providers (HCP). Headache specialists have recognized this sub group of patients who remain refractory to treatment. Despite this recognition, there are no formal criteria that characterize RM.
Elliott, Schulman, Brian E, McGeeney
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Reaching International Consensus on the Definition of Refractory Migraine Using the Delphi Method [PDF]
Aim: Despite its frequency in tertiary headache centers, the International Classification of Headache Disorders, 3rd edition (ICHD-3) does not include refractory migraine.
Lawrence Robbins +2 more
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Open-Label Zonisamide for Refractory Migraine
Clinical Neuropharmacology, 2004Zonisamide is a novel anticonvulsant drug with multiple mechanisms of action, many of which may confer efficacy in the treatment of migraine headaches. This study investigated the use of open-label zonisamide in treating patients with refractory migraine headaches.Thirty-four migraine patients were initiated on a 100-mg/day zonisamide dosage, which was
Miles E, Drake +3 more
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Botox Therapy for Refractory Chronic Migraine
Headache: The Journal of Head and Face Pain, 2005Chronic migraine is unfortunately both common and often resistant to treatment even with prophylactic medications known to be effective in populations with episodic migraine. We undertook an open‐label study to evaluate the safety and utility of botulinum toxin type A injection therapy for patients with chronic migraine who previously had failed to ...
Stafford, Conway +3 more
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Marital migraine: A refractory daily headache
Psychosomatics, 1984Abstract Of forty patients with daily chronic common migraine headaches, only four (17%) of 23 married patients, but 12 (71%) of 17 unmarried patients, responded to prophylactic drug treatment. Unmarried migraine patients were more likely to acknowledge emotional stress and to seek psychotherapy.
H J, Featherstone, B D, Beitman
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Refractory Migraine in a “Just World”
Headache: The Journal of Head and Face Pain, 2014The “just world hypothesis” is the belief that a poor outcome to treatment always implies patient noncompliance. However, all disease states have a spectrum of severity, with the most severe end representing treatment failures despite compliant patients and excellent care.
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Migraine Surgery: A Plastic Surgery Solution for Refractory Migraine Headache
Plastic and Reconstructive Surgery, 2011Migraine headache can be a debilitating condition that confers a substantial burden to the affected individual and to society. Despite significant advancements in the medical management of this challenging disorder, clinical data have revealed a proportion of patients who do not adequately respond to pharmacologic intervention and remain symptomatic ...
Theodore A, Kung +2 more
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Zonisamide for Migraine Prophylaxis in Patients Refractory to Topiramate
Clinical Neuropharmacology, 2009Topiramate is a sulfamate-substituted monosaccharide that has proven efficacy in reducing migraine attacks frequency and severity and has similar mechanisms of action and side effects profile to zonisamide. Although there are some studies suggesting a potential role of this drug in migraine prophylaxis, data are still scarce.
Pedro Emilio, Bermejo, Rodolfo, Dorado
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Droperidol Treatment of Status Migrainosus and Refractory Migraine
Headache: The Journal of Head and Face Pain, 1997We conducted a pilot study of intravenous droperidol in 35 patients (32 women and 3 men; mean age 43 years) with status migrainosus (n=25) or refractory migraine (n=10) in an ambulatory infusion center. Headache was graded as severe in 21 patients and moderate in 14. An intravenous line was started and kept open.
S J, Wang, S D, Silberstein, W B, Young
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