Chronic migraine: treatability, refractoriness, pseudo-refractoriness [PDF]
The Journal of Headache and Pain, 2015 Chronic migraine (CM), a highly disabling condition affecting 2-3% of the general population, represents a difficult-to-treat disorder for its unclear pathophysiology, complex comorbidities, and disappointing response to available pharmacological treatments[1]. High quality evidence (≥2 RCTs) recommends the prophylactic use of onabotulinum toxin A (155-
Barbanti, Piero +4 more
openaire +2 more sources
Prolotherapy in the treatment of chronic migraine — Case report
Headache Medicine, 2023 Introduction Chronic migraine is a socioeconomic and individual burden since it is the largest cause of disability in people under 50 years of age. Although there are several prophylactic drug alternatives, some patients are vulnerable to refractoriness
Ítallo Bernardo Souto +6 more
doaj +1 more source
Diagnostic uncertainty in severe continuous headache: Examining the overlap between status migrainosus, new daily persistent headache, and refractory migraine. [PDF]
HeadachePlain Language Summary When a headache becomes severe and does not stop for months, the diagnosis is not always clear, even when it seems like migraine.
Striegel H, Robblee J.
europepmc +2 more sources
Neuromodulation: Technology at the Neural Interface, EarlyView., 2021 Abstract Background Refractory chronic migraine (rCM) is a highly disabling condition for which novel safe and effective treatments are needed. Safety and long‐term efficacy of paresthesia‐free high cervical 10 kHz spinal cord stimulation (SCS) were here prospectively evaluated for the treatment of rCM.
Adnan Al‐Kaisy +7 more
wiley +1 more source
Review of Interventional Therapies for Refractory Pediatric Migraine
Health Psychology Research, 2023 This is a review of the latest and seminal evidence in pediatric migraine. It covers the etiology and pathophysiology known today, and then will review treatment options, efficacy and safety, quality of data and indications. Though migraine is usually regarded as an infliction in adults, it is not uncommon in the pediatric population and affects up to ...
Jacquelin Peck +16 more
openaire +3 more sources
Motion processing deficits in migraine are related to contrast sensitivity [PDF]
, 2012 Background: There are conflicting reports concerning the ability of people with migraine to detect and discriminate visual motion. Previous studies used different displays and none adequately assessed other parameters that could affect performance, such ...
Shepherd, Alex J. +5 more
core +1 more source
Familial hemiplegic migraine with cerebellar ataxia and paroxysmal psychosis [PDF]
, 1999 Familial hemiplegic migraine is a rare autosomal dominant disorder associated with stereotypic neurologic au ra phenomena including hemiparesis, So far two chromosomal loci have been identified. Families linked to the chromosome 19 locus display missense
Spranger, S. +4 more
core +1 more source
Joint Metabonomic and Instrumental Analysis for the Classification of Migraine Patients with 677-MTHFR Mutations [PDF]
, 2010 Migraine is a neurological disorder that correlates with an increased risk of cerebrovascular lesions. Genetic mutations of the MTHFR gene are correlated to migraine and to the increased risk of artery pathologies.
LIBONI W +17 more
core +1 more source
Identification of predictors of response to Erenumab in a cohort of patients with migraine
Cephalalgia Reports, 2021 Background: The migraine-specific monoclonal antibody Erenumab targeting the calcitonin gene related peptide receptor is an effective and well tolerated preventive treatment of episodic and chronic migraine.
Houssein Salem-Abdou +2 more
doaj +1 more source
Associations between stress and migraine and tension-type headache: Results from a school-based study in adolescents from grammar schools in Germany [PDF]
, 2011 Introduction: Stress is considered the major contributor to migraine and tension-type headache in adolescents. Previous studies have focused on general stressors, whereas the aim of the present study was to investigate associations between individuals ...
Straube, Andreas +15 more
core +1 more source