Results 71 to 80 of about 289,325 (184)

A step toward understanding pediatric occipital neuralgia: Investigating occipital headaches in a pediatric neurology clinic

Headache: The Journal of Head and Face Pain, EarlyView.
Abstract Background Occipital neuralgia (ON) is well characterized in adults but remains poorly understood in children. Pediatric ON may present with overlapping headache features and variable treatment responses, creating diagnostic and management challenges.
Miriam Meghnagi, Christina L. Szperka, Carlyn Patterson Gentile, Charles D. Hwang, Blanca Marquez de Prado, Isha Singh, Elizabeth B. Card, Andrew D. Hershey, Cassandra A. Ligh   +8 more
wiley   +1 more source

Scalp Dysesthesia: Emerging Pathophysiologic Insights and Therapeutic Implications

International Journal of Dermatology, EarlyView.
Scalp dysesthesia is a chronic condition diagnosed through exclusion. This scoping review synthesized data from 59 patients to identify recurrent clinical features, comorbidities, and management strategies that may support earlier diagnosis. Emerging patterns suggest that neuronal sensitization may underlie common symptoms.
Aditya K. Gupta, Jaspreet Kaur, Amanda Liddy, Paradi Mirmirani, Vincent Piguet   +4 more
wiley   +1 more source

Expert Recommendations for Use of Combined Oral Contraceptives in Preadolescent and Young Adolescent Patients With Acne Vulgaris

Pediatric Dermatology, EarlyView.
ABSTRACT Acne vulgaris commonly presents in early adolescence with the onset of adrenarche. Treatments for acne in this age group typically mirror those in older adolescents. However, while combined oral contraceptives are an effective hormonal treatment for acne vulgaris in young women, the safety of using a systemic hormonal therapy in younger ...
Andrea L. Zaenglein, Natalie Allen, Sasigarn Bowden, Hannah R. Chang, Kristina Derrick, Alison Edelman, Dawn Eichenfield, Lawrence Eichenfield, Sarah Gold, Emmy Graber, Julie Harper, Sarah Horvath, Patricia Huguelet, Karin J. Kartawira, Leah Lalor, Irene Lara‐Corrales, Megha M. Tollefson, Tierney E. Wallace, Jonette Keri   +18 more
wiley   +1 more source

Percutaneous Closure of Patent Foramen Ovale for the Treatment of Refractory Migraine Headaches [PDF]

, 2013
Background: Migraine headaches both with and without aura vary in frequency, duration and intensity, affecting the quality of life of up to 10% of the total population. Migraines are treated with both prophylactic and acute medications.
Anderson, Kristina
core  

Chronification of migraine during the climacteric transition and response to advanced preventive therapy: a case report

Headache Medicine
Introduction Migraine is a disabling neurological disorder that predominantly affects women and is strongly influenced by hormonal fluctuations. The climacteric transition may contribute to increased attack frequency and migraine chronification.
Davi Teixeira de Souza, Fernanda Teixeira dos Santos, Ana Carolina Figueiredo Siqueira, Júlia Maria da Silva Cahino Pereira , Ana Victoria Oliveira Sousa   +4 more
doaj   +2 more sources

Advances in Multidimensional Molecular Mechanisms of Epilepsy and Precision Therapy Strategies

CNS Neuroscience &Therapeutics, Volume 32, Issue 11, November 2026.
Epilepsy arises from a multidimensional network imbalance, integrating genetic, inflammatory, and metabolic disruptions. This complexity drives neuronal hyperexcitability and underpins therapeutic challenges. Our review highlights how emerging precision strategies, from targeted molecular therapies to neuromodulation, offer a transformative path toward
Yimin Han, Jingxuan Xu, Yuntian Shen, Jitai Zhang, Xia Li, Xinlei Yao, Lei Qi, Hualin Sun   +7 more
wiley   +1 more source

Refractory chronic migraine associated with Medication-Overuse Headache (MOH): a case report

Headache Medicine
Introduction Chronic migraine is a disabling condition frequently associated with the overuse of acute migraine medications, a factor that contributes to migraine chronification and complicates therapeutic management. This report describes the case of a
Anna Beatriz Prado Costa, Maria Eduarda Cruz de Cerqueira Rodrigues, Luana Carvalho Batista Esteve, Thadson Luiz Vitorio Andrade   +3 more
doaj   +2 more sources

Consensus Guidelines for Diagnosis and Management of Pyruvate Dehydrogenase Complex Deficiency

Journal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Primary pyruvate dehydrogenase complex deficiency (PDCD) comprises a group of monogenic disorders caused by pathogenic variants in genes encoding subunits of, or regulatory components affecting, the pyruvate dehydrogenase complex. The clinical phenotype spans a broad continuum, ranging from early onset congenital lactic acidosis to infantile ...
Nandaki Keshavan, Julia Neugebauer, Marcello Bellusci, Enrico Bertini, Garry Brown, Niklas Darin, Suzanne DeBrosse, Lucy Drexler, Stefan Drexler, Gregory M. Enns, Rebecca D. Ganetzky, Kelly Gilbert, Austin Larson, Rebecca Legi, April N. Lehman, Camile Newby, Manuel Schiff, Rachel Skeath, Peter W. Stacpoole, Sarah Thompson, Emma Watt, Saskia B. Wortmann, Jirair K. Bedoyan, Shamima Rahman   +23 more
wiley   +1 more source

Neurodegenerative Diseases: Epidemiology, Risk Factors, Classification, Pathophysiology, Clinical Features, Diagnosis, and Therapeutic Strategies

MedComm, Volume 7, Issue 11, November 2026.
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He, Jingjing Zeng, Guoqing Wang, Yuxin Li, Feng Zhang   +4 more
wiley   +1 more source

Impact of percutaneous patent foramen ovale closure on migraine course

, 2010
Migraine is a neurological disorder characterized by an increased individual susceptibility to respond to certain triggers by a propagating wave of neuronal depolarization that culminates in typical migraine headaches.
Schwerzmann, Markus, Meier, Bernhard, Bernhard Meier, Markus Schwerzmann   +3 more
core   +1 more source