Results 61 to 70 of about 9,202 (291)

Human Atlas of Tooth Decay Progression: Identification of Cellular Mechanisms Driving the Switch from Dental Pulp Repair Toward Irreversible Pulpitis

Advanced Science, EarlyView.
Tooth decay progression transforms the dental pulp response from repair to fibrosis. At early stages, stromal cells reprogram to repair the extra cellular matrix (ECM), blood vessels, and nerves, remodel and grow, keeping repair possible. In advanced decay, hypoxia, and vessel regression, in complement with an immune switch, fuel nerve degeneration and
Hoang Thai Ha, Sofya Kosmynina, Amandine Verocq, Keremsah Ozen, Ines Tekia, Hugo Bussy, Marie Ramirez, Dima Sabbah, Chloe Goemans, Valerie Vandenbempt, Esteban N. Gurzov, Sumeet Pal Singh, Nicolas Baeyens   +12 more
wiley   +1 more source

Vertical root fracture resistance of simulated immature permanent teeth filled with MTA using different vehicles [PDF]

, 2017
The aim of the study is to evaluate the resistance vertical root fracture (VRF) of mineral trioxide aggregate (MTA) filled-immature permanent roots by using three different vehicles.
Aksel, Hacer, Askerbeyli Örs, Sevinc, Deniz Sungur, Derya   +2 more
core   +1 more source

A Glucose‐Responsive Intelligent Antibacterial and Oxygen‐Producing Hydrogel Promotes the Healing of Diabetic Wounds by Regulating Cellular Heterogeneity

Advanced Science, EarlyView.
We have developed a glucose‐triggered on‐demand drug delivery CF‐CPGaMPN hydrogel based on borate ester bonds. It inactivates microbes, releases oxygen, and enables on‐demand drug release in high‐glucose environments to promote healing of diabetic wounds. Single‐cell sequencing reveals that the CF‐CPGaMPN hydrogel significantly alleviates dysfunctional
Manxuan Liu, Zhongcheng Li, Qian Ren, Ziqian Lu, Yubing Zhang, Yili Guo, Ruomeng Li, Die Hu, Linglin Zhang   +8 more
wiley   +1 more source

Artificial Intelligence in the Field of Endodontics: A Narrative Review

Journal of Primary Care Dentistry and Oral Health
This narrative review explores the applications of artificial intelligence (AI) in endodontics, highlighting its transformative impact on diagnostics, treatment planning, and regenerative procedures.
Atanu Mukhopadhyay, Santanu Mukhopadhyay, Partha Sarathi Mandal   +2 more
doaj   +1 more source

Bioactive Nanofibrous Scaffolds for Regenerative Endodontics [PDF]

Journal of Dental Research, 2013
Here we report the synthesis, materials characterization, antimicrobial capacity, and cytocompatibility of novel antibiotic-containing scaffolds. Metronidazole (MET) or Ciprofloxacin/(CIP) was mixed with a polydioxanone (PDS)polymer solution at 5 and 25 wt% and processed into fibers. PDS fibers served as a control.
Bottino, M.C., Kamocki, K., Yassen, G.H., Platt, J.A., Vail, M.M., Ehrlich, Y., Spolnik, K.J., Gregory, R.L.   +7 more
openaire   +3 more sources

Arginine Methylation Antagonizes TEAD3‐Mediated Repression to Promote Osteogenic Differentiation by Disrupting RUNX2‐Sequestrating Condensates

Advanced Science, EarlyView.
In the unmethylated state, TEAD forms stable, repressive condensates that sequester the osteogenic master regulator RUNX2. Arginine methylation of TEAD at R55 acts as a molecular brake, dissolving these condensates to release RUNX2 and activate the osteogenic program.
Lei Cao, Ruohui Han, Hui Xiong, Qian Li, Shaofei Tao, Xudong Wu, Dayong Liu   +6 more
wiley   +1 more source

In situ biomimetic materials for dentin repair

BMEMat, EarlyView.
This review primarily discusses the role and clinical application of key biomimetic materials for in situ dentin repair, providing a feasible foundation for future material and performance optimization in situ dentin regeneration. Abstract Dental defects, ranking among the most prevalent diseases globally, pose a serious threat to human health, with ...
Jingjing Deng, Siyi Ren, Xuliang Deng, Yan Wei   +3 more
wiley   +1 more source

Unlocking the Power of Amniotic Membrane in Endodontic Care: A Review Article

Journal of Multidisciplinary Dental Research
Amniotic membrane (AM) has garnered significant interest in endodontics for its regenerative properties. This membrane, sourced from the placenta, offers a unique combination of anti-inflammatory, anti-fibrotic, and wound healing properties.
Anisha Deb, Abhinav Kumar
doaj   +1 more source

Regenerative Endodontics – Looking Inward

Journal of Advances in Medicine and Medical Research, 2020
Regenerative endodontics has become a revolutionizing tissue engineering concept in the treatment of immature permanent teeth for over two decades. It has been described as a ‘paradigm shift’ in the treatment of immature teeth, since it fosters continued root maturation.
Tanvi Shah, Shivani Mallishery
openaire   +2 more sources

Exosome as bioactive nanovesicle for diagnostic and therapeutic applications in periodontitis

BMEMat, EarlyView.
This review introduces the mechanism that exosomes participate in the pathogenesis of periodontitis and their potential as biomarkers for early diagnosis and summarizes the application of cell‐ or plant‐derived exosomes or engineered exosomes in periodontitis or periodontal regeneration while proposing the perspective of translational application of ...
Yu Wang, Yuchen Li, Yunfan Zhang, Chenshuang Li, Yifan Lin, Si Chen, Bing Han   +6 more
wiley   +1 more source