Results 71 to 80 of about 3,014,207 (307)

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

FEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux, Christian Lévêque, Fodil Azzaz, Marion Sangiardi, Sarosh R Irani, Michael Seagar, Jacques Fantini, Oussama El Far   +7 more
wiley   +1 more source

Regenerative medicine and cell therapy

European Journal of Histochemistry, 2013
Cell therapies are clinical practices already by decades in fields like blood tumors and severe burns but the term itself when associated with regenerative medicine switch on a cascade of imaginery thoughts that risk to create false hopes; in other words,
Carlo Alberto Redi
doaj   +1 more source

Advances in Regenerative medicine [PDF]

, 2011
PREFACE In order to better introduce this book, it is important to define regenerative medicine as this field is built through a combination of multiple elements including living cells, matrix to support the living cells (i.e.

core  

Unveiling the potential of melt electrowriting in regenerative dental medicine [PDF]

, 2023
For nearly three decades, tissue engineering strategies have been leveraged to devise effective therapeutics for dental, oral, and craniofacial (DOC) regenerative medicine and treat permanent deformities caused by many debilitating health conditions.
Malda, Jos, Daghrery, Arwa, Bottino, Marco C, Bottino, Marco C., Araújo, Isaac J. de Souza, de Souza Araújo, Isaac J., de Souza Araújo, Isaac J, Castilho, Miguel   +7 more
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Spatiotemporal readiness is key to preparing regenerative medicine for the clinic [PDF]

, 2021
Copyright © 2021 The Author(s). Successful translation of regenerative medicine projects to the clinic requires attention to the complex interaction of spatial and timing issues from manufacturing to clinical use.Wellcome Trust (WT218807/Z/19/Z, WT208198/
Martin, P., Martin, Paul, Stephens, N; id_orcid, Morrison, Michael, Hogle, Linda, Stephens, Neil, Stephens, N., Hogle, L, Morrison, M, Stephens, N, Morrison, M., Martin, P, Hogle, L.   +12 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Regenerative medicine in otorhinolaryngology [PDF]

The Journal of Laryngology & Otology, 2015
AbstractBackground:Tissue engineering using biocompatible scaffolds, with or without cells, can permit surgeons to restore structure and function following tissue resection or in cases of congenital abnormality. Tracheal regeneration has emerged as a spearhead application of these technologies, whilst regenerative therapies are now being developed to ...
Wormald, J, Fishman, J, Juniat, S, Tolley, N, Birchall, M   +4 more
openaire   +2 more sources

MicroRNAs in Tissue Engineering and Regenerative Medicine

, 2015
The body has a large regenerative capacity to cope with the continuous adverse challenges of high-calorie diets, aging, inflammation, and wear and tear, as well as acute injuries such as myocardial infarction.
Sen, Chandan, Harmsen, Martin, Krenning, Guido   +2 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source