Results 71 to 80 of about 3,835,856 (260)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Regenerative biology and medicine /

, 2012
Since the publication of the first edition of Regenerative Biology and Medicine in 2006, steady advances have been made in understanding the origin and characteristics of stem cells in epithelia, skeletal muscle, and bone, and in the niche signals that ...
Stocum, David L.
core  

Cell-Based Therapy for Cancer in Regenerative Medicine

Regenerative medicine focuses on developing and applying new cell-based therapies to heal tissues and organs and restore function lost due to aging, disease, tissue damage, or cancer. Cancer is a complex disease. It can occur with dysfunction in multiple
Oǧuz, Fatma Savran, Sel, Figen Abatay
core   +1 more source

Advances in Regenerative medicine [PDF]

, 2011
PREFACE In order to better introduce this book, it is important to define regenerative medicine as this field is built through a combination of multiple elements including living cells, matrix to support the living cells (i.e.

core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A blueprint for the next generation of ELSI research, training, and outreach in regenerative medicine

, 2017
Regenerative medicine has attracted the interest of scientists, physicians, and patient communities, and as well as policy-makers and the broader public given related ethical, legal, and social implications.
Jennifer McCormick, McCormick, Jennifer, Rossi, Fabio, Amy Zarzeczny, Ravitsky, Vardit, Judy Illes, Shelly Benjaminy, Master, Zubin, Ubaka Ogbogu, Kleiderman, Erika, Brenda Wilson, Zarzeczny, Amy, Rosario Isasi, Ogbogu, Ubaka, Robillard, Julie M, Wilson, Brenda, Douglas Sipp, Erika Kleiderman, Lomax, Geoff, Fabio Rossi, Sipp, Douglas, Benjaminy, Shelly, Vardit Ravitsky, Zubin Master, Geoff Lomax, Illes, Judy, Isasi, Rosario, Julie M. Robillard   +27 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Are agricultural and natural sources of bio-products important for modern regenerative medicine? A review [PDF]

, 2017
Introduction and objectives As tissue engineering and regenerative medicine have continued to evolve within the field of biomedicine, the fundamental importance of bio-products has become increasingly apparent.
Tomasz Drewa, Kloskowski, Tomasz, Tomasz Kloskowski, Warda, Karolina, Dominik Tyloch, Nowacka, Katarzyna, Katarzyna Nowacka, Karolina Warda, Maciej Nowacki, Marta Pokrywczyńska, Pokrywczyńska, Marta, Tyloch, Dominik, Marta Rasmus, Drewa, Tomasz, Nowacki, Maciej, Rasmus, Marta   +15 more
core   +2 more sources

Regenerative Medicine for the Kidney [PDF]

Urogenital Tract Infection
Kidney disease poses a major and growing global health challenge, with both prevalence and mortality continuing to rise. Current standard-of-care treatments, including dialysis and kidney transplantation, have significant limitations and do not ...
Vladimir Mashanov, Ji Hyun Kim
doaj   +1 more source