Results 111 to 120 of about 32,974 (279)

Regioselectivity of the Claisen rearrangement of meta- and para-substituted allyl aryl ethers [PDF]

The regioselectivity of the Claisen rearrangement with different meta-substituted and meta- and para-substituted allyl phenyl ethers was investigated.
William Thomas, Möller, Svava Dögg, Hreinsdóttir, Benjamín Ragnar, Sveinbjörnsson, Luis Antonio, Arana   +3 more
core   +3 more sources

Electronic and Steric Effects Control Regioselectivity in Alkyne Migratory Insertion during Ni-Catalyzed Indenone Synthesis

, 2023
Many useful transition-metal-catalyzed reactions depend on the migratory insertion of an alkyne into a metal–carbon bond. Steric effects, electronic effects, and coordinating directing groups have all been shown to control product distributions in ...
Logan M. Whitt (14657791), Lydia P. Moore (14657782), Mei Lin N. Dye (12210763), Zachary J. Hagedorn (14657785), Dale J. Wilger (2028226), Megan E. Barnes (14657788)   +5 more
core   +1 more source

Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450

Journal of Lipid Research, 2010
Cytochromes P450 (CYPs) metabolize polyunsaturated long-chain fatty acids (PUFA-LC) to several classes of oxygenated metabolites. Through use of human recombinant CYPs, we recently showed that CYP1A1, -2C19, -2D6, -2E1, and -3A4 are mainly hydroxylases ...
Danièle Lucas, Sophie Goulitquer, Jan Marienhagen, Maude Fer, Yvonne Dreano, Ulrich Schwaneberg, Yolande Amet, Laurent Corcos   +7 more
doaj   +1 more source

Ligand-Controlled Regioselectivity in Palladium-Catalyzed Cross Coupling Reactions

, 2016
Ligand-Controlled Regioselectivity in Palladium-Catalyzed Cross Coupling ...
Franziska Schoenebeck (1266411), K. N. Houk (1247004)   +1 more
core   +1 more source

Atypical Condensation Domains Guide Discovery and Illuminate Biosynthesis of Myxoglucamides Featuring Vinyl‐Substituted, α‐Oxidized γ‐Amino Acids

Angewandte Chemie, EarlyView.
Genome mining of atypical condensation (C) domains leads to the discovery of myxoglucamides, glycolipopeptides featuring an unprecedented vinyl‐substituted, α‐oxidized γ‐amino acid. Biosynthetic studies reveal a discrete C‐domain‐like O‐acyltransferase, a β‐hydroxylation‐dependent chain‐extension checkpoint, and an unusual pathway for γ‐amino acid ...
Tingting Wang, Alexander Popoff, Maja Hunter, Guangzhi Dai, Ronald Garcia, Huixin Xu, Haowen Zhao, Asfandyar Sikandar, Liujie Huo, Rolf Müller, Chengzhang Fu   +10 more
wiley   +2 more sources

Regioselectivity-Switchable Hydroarylation of Styrenes

, 2016
Cobalt−phosphine and cobalt−carbene catalysts have been developed for the hydroarylation of styrenes via chelation-assisted C−H bond activation, to afford branched and linear addition products, respectively, in a highly regioselective fashion.
Ke Gao (1521607), Naohiko Yoshikai (1479319)   +1 more
core   +1 more source

Dyotropic Rearrangement of Hypervalent Iodine Species: Migrative Heterofunctionalization of Quaternary Carbons

Angewandte Chemie, EarlyView.
1,2‐Aryl migration involving in situ‐generated alkyl iodine(III) species proceeds through a previously unrecognized 1,2‐C/I(III) dyotropic rearrangement. Migratory aryl fluorination, acetoxylation, and alkoxylation of 2‐alkyl‐2‐aryl‐3‐iodopropanoates provide α‐heterofunctionalized products, accompanied by aryl migration from the α‐ to the β‐position ...
Chen‐Xu Liu, Qian Wang, Matthew D. Wodrich, Jieping Zhu   +3 more
wiley   +2 more sources

Aerobic addition of secondary phosphine oxides to vinyl sulfides: a shortcut to 1-hydroxy-2-(organosulfanyl)ethyl(diorganyl)phosphine oxides

Beilstein Journal of Organic Chemistry, 2015
Secondary phosphine oxides react with vinyl sulfides (both alkyl- and aryl-substituted sulfides) under aerobic and solvent-free conditions (80 °C, air, 7–30 h) to afford 1-hydroxy-2-(organosulfanyl)ethyl(diorganyl)phosphine oxides in 70–93% yields.
Svetlana F. Malysheva, Alexander V. Artem’ev, Nina K. Gusarova, Nataliya A. Belogorlova, Alexander I. Albanov, C. W. Liu, Boris A. Trofimov   +6 more
doaj   +1 more source

The regioselective aminohydroxylation of allylic carbamates

Chemical Communications, 2001
The synthesis and aminohydroxylation of a series of acyclic allylic carbamates is described: the formation of a putative O=Os=NR linkage between the transition metal and substrate is proposed to account for the high levels of regioselectivity that were observed; proof of the structure of one of the aminohydroxylation products was obtained through X-ray
Donohoe, T, Johnson, P, Helliwell, M, Keenan, M   +3 more
openaire   +2 more sources

1,4‐Brook Rearrangement of β‐Silyl Allylic Alcohols: Trisubstituted Alkenes by Copper‐Mediated Stereoretentive ipso‐Substitution Reactions

Angewandte Chemie, EarlyView.
To fully leverage the power of the ruthenium‐catalyzed trans‐hydrosilylation of propargyl alcohols, it was necessary to develop a practical and robust method for the activation of those products that carry the silyl group distal to the hydroxy substituent.
Paul Haf‐Moths, Jack L. Sutro, Alois Fürstner   +2 more
wiley   +2 more sources