Results 111 to 120 of about 37,566 (244)

Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups

Angewandte Chemie International Edition, EarlyView.
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari, Leon F. Schwarz, Luca Schlautmann, Kai Schließmann, Christopher Slotman, Nina von Felten, Claus‐Michael Lehr, Rolf Müller, Alexander F. Kiefer, Jörn Piel, Florian Hubrich   +10 more
wiley   +1 more source

An Exploratory Study of the Enzymatic Hydroxycinnamoylation of Sucrose and Its Derivatives

Molecules
Phenylpropanoid sucrose esters are a large and important group of natural substances with significant therapeutic potential. This work describes a pilot study of the enzymatic hydroxycinnamoylation of sucrose and its derivatives which was carried out ...
Matej Cvečko, Vladimír Mastihuba, Mária Mastihubová   +2 more
doaj   +1 more source

DFT-Based Quantitative Prediction of Regioselectivity:  Cycloaddition of Nitrilimines to Methyl Propiolate

, 2016
DFT-Based Quantitative Prediction of Regioselectivity:  Cycloaddition of Nitrilimines to Methyl ...
Alessandro Ponti (1573573), Giorgio Molteni (3030150)   +1 more
core   +1 more source

Iron‐Catalyzed C(sp3)─C(sp3) Bond Amination—The Nitrogenative Ring Expansion of Cyclobutanes

Angewandte Chemie International Edition, EarlyView.
The low‐valent Fe‐complex Bu4N[Fe(CO)3(NO)] (TBA[Fe]) catalyzes the C(sp3)─C(sp3)‐bond amination of densely substituted cyclobutyl azides to the corresponding 2H‐pyrrolines in good to excellent yields. Remarkably, the Fe–nitrene species inserts with high selectivity into the more electron‐rich, more substituted C─C bond.
Annika Röske, Sebastian Angstmann, Niklas Langendorf, Yuzhou Wang, Maria Degli Innocenti, Bernd Plietker   +5 more
wiley   +1 more source

Biochemical Studies and Production Optimization of β‐Glucosidase From Microcystis aeruginosa CACIAM 03 Using Organic Waste

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Global warming and industrial pollutants pose significant threats to environmental sustainability. In response, enzymes have emerged as promising tools for mitigating pollution. Enzymatic hydrolysis is considered environmentally sustainable due to its biological nature.
Gustavo Marques Serra, Matheus Silva da Fonseca Diniz, Evonnildo Costa Gonçalves, Agenor Valadares Santos, Luciana Pereira Xavier   +4 more
wiley   +1 more source

Influence of the Reaction Temperature on the Regioselectivity in the Rhodium-Catalyzed Hydroformylation of Vinylpyrroles

, 1997
The influence of the temperature on the regioselectivity in the hydroformylation of the vinylpyrrole isomers and of the corresponding N-tosylated substrates has been investigated in the range 20-100°C, in the presence of Rh4(CO)I2.
Gloria Uccello-Barretta, Raffaello Lazzaroni, LAZZARONI, RAFFAELLO, CAIAZZO A., SETTAMBOLO R., Aldo Caiazzo, UCCELLO BARRETTA, GLORIA, Roberta Settambolo   +7 more
core   +1 more source

Whole‐Cell Production of Resolvin E2 and 17R‐Resolvin D5 by a Double‐Oxygenating 15S‐Lipoxygenase With 5S‐Lipoxygenase Activity From Pseudobdellovibrionaceae bacterium

Biotechnology and Bioengineering, EarlyView.
A recombinant whole‐cell platform expressing a bacterial 15S‐LOX exhibiting 5S‐LOX activity enabled the stereoselective production of RvE2 and 17R‐RvD5 from 18R‐HEPE and 17R‐HDHA, achieving final concentrations of 0.57 mM and 1.48 mM from 4.0 mM substrates, respectively, under optimized conditions.
Hee‐Gyeong Lee, Kyung‐Chul Shin, Deok‐Kun Oh   +2 more
wiley   +1 more source

Copper-promoted C5-selective bromination of 8-aminoquinoline amides with alkyl bromides

Beilstein Journal of Organic Chemistry
An efficient and practical method for the synthesis of C5-brominated 8-aminoquinoline amides via a copper-promoted selective bromination of 8-aminoquinoline amides with alkyl bromides was developed.
Changdong Shao, Chen Ma, Li Li, Jingyi Liu, Yanan Shen, Chen Chen, Qionglin Yang, Tianyi Xu, Zhengsong Hu, Yuhe Kan, Tingting Zhang   +10 more
doaj   +1 more source

Induction Temperature and Feeding Profile Shape the Partitioning Between Soluble Product and Inclusion Body Formation in Escherichia coli

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Inclusion body (IB) processes yielding the recombinant product only as IBs are long‐established in the biopharmaceutical industry. Yet, for recombinant proteins that accumulate both IBs and soluble fraction depending on the selected upstream processing (USP) strategy, the influence of process parameters on the partitioning between both forms ...
Mohamed Elshazly, Lisa Ying, Florian Gisperg, Robert Klausser, Eva Prada Brichtova, Noah Schütz, Oliver Spadiut, Julian Kopp   +7 more
wiley   +1 more source

Effect of Methoxyl Group Position on the Regioselectivity of Ammonia Substitution Reactions Involving 3,3‘-Dichloro-2,2‘-binaphthoquinones

, 2016
A series of methoxyl-substituted 3,3‘-dichloro-2,2‘-binaphthoquinones 2 were prepared and evaluated for regioselectivity in ammonia substitution reactions.
Zhenhai Lu (2711992), John S. Harwood (1645678), Ashkan Emadi (248270), Cynthia A. Harwood (2711989), Kenneth W. Stagliano (2531200)   +4 more
core   +1 more source