Results 91 to 100 of about 32,974 (279)
Molecules, 2019 The [3 + 2] cycloaddition (32CA) reaction of an α-santonin derivative, which has an exocyclic C⁻C double bond, with p-bromophenyl nitrile oxide yielding only one spiroisoxazoline, has been studied within the molecular electron density theory ...
Luis R. Domingo +2 more
doaj +1 more source
Regioselectivity in the Nitration of Dialkoxybenzenes
, 2016 Dinitrodialkoxybenzene derivatives are important precursors for Schiff base macrocycles and a variety of other molecules. During our investigations, we have found that the dinitration reaction of 1,2-dialkoxybenzenes proceeds with unusual ...
Kevin Shopsowitz (2226526) +2 more
core +1 more source
Angewandte Chemie, EarlyView.Highly electrophilic N‐radical cations enable efficient and selective H‐atom transfer (HAT) of unprotected amines. In this exceedingly practical strategy, simple CuCl catalyzes an interrupted Hofmann–Löffler–Freytag (HLF) reaction to afford δ desaturated amines, aza‐heterocycles, and C─H aminated alkanes without protecting groups.
Pavitra Laohapaisan +6 more
wiley +2 more sources
Molecules, 2016 The enzymatic regioselective monopalmitoylation of racemic 9-(2,3-dihydroxypropyl)- adenine (DHPA), an approved antiviral agent, has been performed by an immobilized form of Candida antarctica B lipase (CAL-B) using a 4:1 DMF/hexane mixture as the ...
Jana Brabcová +5 more
doaj +1 more source
Engineering the substrate specificity and regioselectivity of Burkholderia thailandensis lipoxygenase [PDF]
Lipoxygenases (LOXs) catalyze the regioselective dioxygenation of polyunsaturated fatty acids (PUFAs), generating fatty acid hydroperoxides (FAHPs) with diverse industrial applications.
Vincken, Jean-Paul +4 more
core +1 more source
Angewandte Chemie, EarlyView.The cooperative reactivity characteristic of molecular dinuclear nickel complexes is transferred to mesoporous silica through a systematic immobilization strategy. The resulting material preserves the key features of the bimetallic motif within a robust heterogeneous framework, demonstrating how molecular design principles can be translated into well ...
Jitpisut Poolwong +4 more
wiley +2 more sources
Molecules, 2014 Chlorinated ethenes are prevalent groundwater contaminants. To better constrain (bio)chemical reaction mechanisms of reductive dechlorination, the position-specificity of reductive trichloroethene (TCE) dehalogenation was investigated.
Stefan Cretnik +4 more
doaj +1 more source
Regioselective Substitution of BINOL
Chemical Reviews1,1'-Bi-2-naphthol (BINOL) has been extensively used as the chirality source in the fields of molecular recognition, asymmetric synthesis, and materials science. The direct electrophilic substitution at the aromatic rings of the optically active BINOL has been developed as one of the most convenient strategies to structurally modify BINOL for diverse ...
openaire +2 more sources
, 2010 P450 3A4, the most important human CYP enzyme, is responsible for the metabolism of more than 50%-60% of clinically used drugs. Early knowing the site of metabolism will help the medicinal chemist to decide how best to block the metabolism of candidates ...
艾纯芝, 杨凌, 毛玉玺
core
Investigating the Influence of Various Migratory Allyl Ethers on the Regioselectivity of the Aromatic Claisen Rearrangement [PDF]
, 2023 We report an investigation into the regioselectivity of the aromatic Claisen rearrangement within a novel asymmetric substrate that possesses an internal base meta to the aryl allyl ether position.
Brown, Logan E. +1 more
core