Results 121 to 130 of about 32,974 (279)

Regioselectivity in the ring opening of non-activated aziridines

, 2012
In this critical review, the ring opening of non-activated 2-substituted aziridines via intermediate aziridinium salts will be dealt with. Emphasis will be put on the relationship between the observed regioselectivity and inherent structural features ...
Michel Waroquier, Ha, Hyun-Joon, Eum, Heesung, Matthias D'hooghe, Catak, Saron, Sonja Stanković, D'hooghe, Matthias, Hyun-Joon Ha, De Kimpe, Norbert, Veronique Van Speybroeck, Stanković, Sonja, Norbert De Kimpe, Waroquier, Michel, Heesung Eum, Van Speybroeck, Veronique, Saron Catak   +15 more
core   +1 more source

Electrocatalytic Polarity Inversion of Azlactones: Access to α‐Quaternary Amino Acids with Electron‐Rich SOMOphiles

Angewandte Chemie, EarlyView.
Electrocatalytic polarity inversion of azlactones unlocks their coupling with electron‐rich reaction partners. Triarylamine‐mediated oxidation of the azlactone enolate generates an electrophilic radical intermediate that undergoes selective C4 functionalization with diverse SOMOphiles.
Paula Rodríguez, David Buedo, Alberto Vega‐Peñaloza, Kian Gosling, Stuart C. D. Kennington, Bart Limburg, Xavier Companyó   +6 more
wiley   +2 more sources

Boronate‐Type‐Controlled Regioselective Catalytic [2 + 2 + 2] Cyclotrimerization for Synthesis of Polysubstituted 2‐ and 3‐Borylated Pyridines

ChemistryEurope
Regioselective synthesis is a crucial concept in organic chemistry, enabling the selective formation of different regioisomers from the same type of starting materials.
Eva Bednářová, David Nečas, Rahamdil Usman, Anagha K. Satheeshkumar, Róbert Gyepes, Ivana Císařová, Marko Hapke, Martin Kotora   +7 more
doaj   +1 more source

Study on the Alkylation Reactions of N(7)-Unsubstituted 1,3-Diazaoxindoles

Molecules, 2017
The chemistry of the 5,7-dihydro-6H-pyrrolo[2,3-d]pyrimidin-6-one (1,3-diazaoxindole) compound family, possessing a drug-like scaffold, is unexplored. In this study, the alkylation reactions of N(7)-unsubstituted 5-isopropyl-1,3-diazaoxindoles bearing ...
Eszter Kókai, Judit Halász, András Dancsó, József Nagy, Gyula Simig, Balázs Volk   +5 more
doaj   +1 more source

TBAF and Cellulose Esters: Unexpected Deacylation with Unexpected Regioselectivity

, 2016
Tetrabutylammonium fluoride has been found to catalyze the deacylation of cellulose esters. More surprisingly, the deacylation is highly regioselective.
Kevin J. Edgar (1495768), Daiqiang Xu (2066866)   +1 more
core   +1 more source

Water, Alcohols, Amines, and Amides as Formal Hydrogen‐Atom‐Transfer Reagents Through Activation With Redox‐Active Lewis Acids

Angewandte Chemie, EarlyView.
Protic molecules containing strong O─H or N─H bonds typically resist hydrogen‐atom abstraction because of the high reactivity of the resulting heteroatom‐centered radicals. However, association of the protic molecules with redox‐active Lewis acids can provide powerful hydrogen‐atom donors or proton‐coupled‐electron‐transfer reagents.
Petra Vojáčková, Armido Studer
wiley   +2 more sources

Sulfur‐Boron Lewis Pair‐Catalyzed Hydrohalogenation of Alkynes via Formal Hydrogen Atom Transfer

Angewandte Chemie, EarlyView.
A sulfur‐boron Lewis pair enables the stereodivergent hydrohalogenation of alkynes with exclusive Markovnikov selectivity. Mechanistic studies support a proton transfer‐electron transfer (PT‐ET) sequence for vinyl radical formation rather than a concerted hydrogen atom transfer (HAT) pathway.
Yun Soo Shim, Jin Qian, Sourav Dey, Andrew F. Zahrt, Hyung Min Chi   +4 more
wiley   +2 more sources

An Exploratory Study of the Enzymatic Hydroxycinnamoylation of Sucrose and Its Derivatives

Molecules
Phenylpropanoid sucrose esters are a large and important group of natural substances with significant therapeutic potential. This work describes a pilot study of the enzymatic hydroxycinnamoylation of sucrose and its derivatives which was carried out ...
Matej Cvečko, Vladimír Mastihuba, Mária Mastihubová   +2 more
doaj   +1 more source

Regioselectivity of Birch Reductive Alkylation of Biaryls^†

, 2016
The regioselectivity of the Birch reductive alkylation of polysubstituted biaryls has been investigated. Results indicate that regioselectivity is affected by the electronic nature of substituents on both aromatic rings.
Raphaël Lebeuf (2524504), Frédéric Robert (2474788), Yannick Landais (1528861)   +2 more
core   +1 more source

1,2‐Bis(boronate) Arenes by Borylation Directed Borylation

Angewandte Chemie, EarlyView.
Boron electrophiles derived from tetrabromo‐pyrazaboles and AlCl3 affect the regioselective vicinal double C–H borylation of a range of arenes and polycyclic aromatic hydrocarbons (PAHs). A subsequent pinacol installation step then affords the vicinal bis‐boronate ester‐substituted arene/PAH.
Anna V. Schellbach, Mathew J. Cross, Emily Noone, Cate S. Anstöter, Michael J. Ingleson   +4 more
wiley   +2 more sources